T细胞抗原特异性免疫应答的调控机制
31530022
2015
C0802.适应性免疫
许琛琦
重点项目
研究员
中国科学院分子细胞科学卓越创新中心
282万元
抗原识别;T细胞;免疫应答;T细胞抗原受体
2016-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 一种包含具有Y/F突变的CD3ε胞内区的嵌合抗原受体及其用途 | 专利 | 许琛琦;周秋萍;吴微;徐心怡;何星 |
| 2 | 中青年科技创新领军人才 | 奖励 | 许琛琦 |
| 3 | Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism | 期刊论文 | Yang Wei;Bai Yibing;Xiong Ying;Zhang Jin;Chen Shuokai;Zheng Xiaojun;Meng Xiangbo;Li Lunyi;Wang Jing;Xu Chenguang;Yan Chengsong;Wang Lijuan;Chang Catharine C. Y.;Chang Ta-Yuan;Zhang Ti;Zhou Penghui;Song Bao-Liang;Liu Wanli;Sun Shao-cong;Liu Xiaolong;Li Bo-liang;Xu Chenqi |
| 4 | Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy | 期刊论文 | Li Wentao;Qiu Shizhen;Chen Jian;Jiang Shutan;Chen Wendong;Jiang Jingwei;Wang Fei;Si Wen;Shu Yilai;Wei Ping;Fan Gaofeng;Tian Ruijun;Wu Haitao;Xu Chenqi;Wang Haopeng |
| 5 | 一种嵌合抗原受体及其用途 | 专利 | 许琛琦;周秋萍;吴微;何星;孙赫 |
| 6 | Regulation of T cell signalling by membrane lipids | 期刊论文 | Wu Wei;Shi Xiaoshan;Xu Chenqi |
| 7 | 国家“万人计划”领军人才 | 奖励 | 许琛琦 |
| 8 | Intramembrane ionic protein-lipid interaction regulates integrin structure and function. | 期刊论文 | Guo Jun;Zhang Youhua;Li Hua;Chu Huiying;Wang Qinshu;Jiang Shutan;Li Yan;Shen Hongbin;Li Guohui;Chen Jianfeng;Xu Chenqi |
| 9 | 一种包含CD3ε胞内碱性氨基酸富集区基序的嵌合抗原受体及其用途 | 专利 | 许琛琦;周秋萍;吴微;徐心怡;何星 |
| 10 | Multiple signaling roles of CD3e and its application in CAR-T cell therapy | 期刊论文 | Wu Wei;Zhou Qiuping;Masubuchi Takeya;Shi Xiaoshan;Li Hua;Xu Xinyi;Huang Min;Meng Li;He Xing;Zhu Hengyu;Gao Shuaixin;Zhang Nan;Jing Ruirui;Sun Jie;Wang Haopeng;Hui Enfu;Wong Catherine Chiulan;Xu Chenqi |
| 11 | 上海市青年杰出贡献奖 | 奖励 | 许琛琦 |
| 12 | Dynamic regulation of CD28 conformation and signaling by charged lipids and ions | 期刊论文 | Yang Wei;Pan Weiling;Chen Shuokai;Trendel Nicola;Jiang Shutan;Xiao Feng;Xue Manman;Wu Wei;Peng Zeli;Li Xiaoxi;Ji Hongbin;Liu Xiaolong;Jiang Hai;Wang Haopeng;Shen Hongbin;Dushek Omer;Li Hua;Xu Chenqi |
| 13 | Ionic protein–lipid interactions at the plasma membrane regulate the structure and function of immunoreceptors | 期刊论文 | Li Hua;Yan Chengsong;Guo Jun;Xu Chenqi |
| 14 | Immune checkpoint signaling and cancer immunotherapy | 期刊论文 | He Xing;Xu Chenqi |
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