SIRT2在灵长类心肌衰老进程中的作用及其机制研究
32000510
2020
C0705.细胞衰老、死亡及自噬
范艳玲
青年科学基金项目
助理研究员
中国科学院北京基因组研究所（国家生物信息中心）
24万元
基因编辑;多组学;SIRT2;心脏衰老（heart aging）
2021-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A single-cell transcriptomic landscape of the lungs of patients with COVID-19 | 期刊论文 | Si Wang;Xiaohong Yao;Shuai Ma;Yifang Ping;Yanling Fan;Shuhui Sun;Zhicheng He;Yu Shi;Liang Sun;Shiqi Xiao;Moshi Song;Jun Cai;Jiaming Li;Rui Tang;Liyun Zhao;Chaofu Wang;Qiaoran Wang;Lei Zhao;Huifang Hu;Xindong Liu;Guoqiang Sun;Lu Chen;Guoqing Pan;Huaiyong Chen;Qingrui Li;Peipei Zhang;Yuanyuan Xu;Huyi Feng;Guo-Guang Zhao;Tianzi Wen;Yungui Yang;Xuequan Huang;Wei Li;Zhenhua Liu;Hongmei Wang;Haibo Wu;Baoyang Hu... |
| 2 | Determining a multimodal aging clock in a cohort of Chinese women | 期刊论文 | Jiaming Li;Muzhao Xiong;Xiang-Hong Fu;Yanling Fan;Chen Dong;Xiaoyan Sun;Fang Zheng;Si-Wei Wang;Lixiao Liu;Ming Xu;Cui Wang;Jiale Ping;Shanshan Che;Qiaoran Wang;Kuan Yang;Yuesheng Zuo;Xiaoyong Lu;Zikai Zheng;Tian Lan;Si Wang;Jing Qu;Yongbiao Xue;Yun-Gui Yang;Feng Zhang;Weiqi Zhang;Guang-Hui Liu |
| 3 | CRISPR-based screening identifies XPO7 as a positive regulator of senescence | 期刊论文 | Lan-Zhu Li;Kuan Yang;Yaobin Jing;Yanling Fan;Xiaoyu Jiang;Si Wang;Guang-Hui Liu;Jing Qu;Shuai Ma;Weiqi Zhang |
| 4 | SIRT2 counteracts primate cardiac aging via deacetylation of STAT3 that silences CDKN2B | 期刊论文 | Yanxia Ye;Kuan Yang;Haisong Liu;Yang Yu;Moshi Song;Daoyuan Huang;Jinghui Lei;Yiyuan Zhang;Zunpeng Liu;Qun Chu;Yanling Fan;Sheng Zhang;Yaobin Jing;Concepcion Rodriguez Esteban;Si Wang;Juan Carlos Izpisua Belmonte;Jing Qu;Weiqi Zhang;Guang-Hui Liu |
| 5 | Resurrection of endogenous retroviruses during aging reinforces senescence | 期刊论文 | Xiaoqian Liu;Zunpeng Liu;Zeming Wu;Jie Ren;Yanling Fan;Liang Sun;Gang Cao;Yuyu Niu;Baohu Zhang;Qianzhao Ji;Xiaoyu Jiang;Cui Wang;Qiaoran Wang;Zhejun Ji;Lanzhu Li;Concepcion Rodriguez Esteban;Kaowen Yan;Wei Li;Yusheng Cai;Si Wang;Aihua Zheng;Yong E. Zhang;Shengjun Tan;Yingao Cai;Moshi Song;Falong Lu;Fuchou Tang;Weizhi Ji;Qi Zhou;Juan Carlos Izpisua Belmonte;Weiqi Zhang;Jing Qu;Guang-Hui Liu |
| 6 | Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging | 期刊论文 | Yiyuan Zhang;Yandong Zheng;Si Wang;Yanling Fan;Yanxia Ye;Yaobin Jing;Zunpeng Liu;Shanshan Yang;Muzhao Xiong;Kuan Yang;Jinghao Hu;Shanshan Che;Qun Chu;Moshi Song;Guang-Hui Liu;Weiqi Zhang;Shuai Ma;Jing Qu |
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