肿瘤靶向纳米载体-生物降解水凝胶响应性转变体系的构筑、调控及其在肿瘤治疗中的应用研究

81601606
2016
H2808.纳米医学
陈鑫
青年科学基金项目
研究员
西安交通大学
17万元
肿瘤靶向治疗;介孔二氧化硅;肿瘤实时跟踪;响应性水凝胶;长周期药物控释
2017-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 MiRNA Delivery System Based on Stimuli-Responsive Gold Nanoparticle Aggregates for Multimodal Tumor Therapy 期刊论文 Xiangdong Wang;Nuo Jin;Qiao Wang;Tao Liu;Kangcan Liu;Yan Li;Yongkang Bai;Xin Chen
2 Stepwise co-delivery of an enzyme and prodrug based on a multi-responsive nanoplatform for accurate tumor therapy 期刊论文 Li Chen;Zhongning Liu;Ronghua Jin;Xiaoshan Yang;Yongkang Bai;Shiyu Liu;Xin Chen
3 Intracellular Enzyme-Triggered Assembly of Amino Acid-Modified Gold Nanoparticles for Accurate Cancer Therapy with Multimode 期刊论文 Liu Tao;Jin Ronghua;Yuan Pingyun;Bai Yongkang;Cai Bolei;Chen Xin
4 One-pot preparation of polymer microspheres with different porous structures to sequentially release bio-molecules for cutaneous regeneration 期刊论文 Yuan Pingyun;Qiu Xinyu;Jin Ronghua;Bai Yongkang;Liu Shiyu;Chen Xin
5 A Thermal-, Water-, and Near-Infrared Light-Induced Shape Memory Composite Based on Polyvinyl Alcohol and Polyaniline Fibers 期刊论文 Bai Yongkang;Zhang Jiwen;Chen Xin
6 Substrate-Independent Coating with Persistent and Stable Antifouling and Antibacterial Activities to Reduce Bacterial Infection for Various Implants 期刊论文 Yuan Pingyun;Qiu Xinyu;Wang Xinran;Tian Ran;Wang Lin;Bai Yongkang;Liu Shiyu;Chen Xin
7 一种具有基底普适性和持久稳定性的防污抗菌涂层的制备方法 专利 陈鑫;袁萍耘;白永康
8 Fabrication of remote controllable devices with multistage responsiveness based on a NIR light-induced shape memory ionomer containing various bridge ions 期刊论文 Bai Yongkang;Zhang Jiwen;Wen Didi;Yuan Bo;Gong Peiwei;Liu Jiamei;Chen Xin
9 On- demand tailored mesoporous silica nanoparticles as a theranostic platform for tumor therapy 专著 Xin Chen;Ronghua Jin;Xiangdong Wang;Li Chen;Qiao Wang;Xiaoyan Guo
10 Dual responsive hydrogels based on functionalized mesoporous silica nanoparticles as an injectable platform for tumor therapy and tissue regeneration 期刊论文 Chen Xin;Yuan Pingyun;Liu Zhongning;Bai Yongkang;Zhou Yongsheng
11 一种具有智能抗菌和长效生物分子释放功能的快速自修复凝胶的制备方法和应用 专利 陈鑫;田然;袁萍耘;陈莉;张继雯;田雨
12 Redox-Responsive Nanogel with Intracellular Reconstruction and Programmable Drug Release for Targeted Tumor Therapy 期刊论文 Tian Yu;Tian Ran;Li Chen;Jin Ronghua;Feng Yiming;Bai Yongkang;Chen Xin
13 Redox-Responsive Supramolecular Micelles for Targeted Imaging and Drug Delivery to Tumor 期刊论文 Liu Tao;Liu Zhongning;Chen Jiachen;Jin Ronghua;Bai Yongkang;Zhou Yongsheng;Chen Xin
14 Core-Satellite Mesoporous Silica-Gold Nanotheranostics for Biological Stimuli Triggered Multimodal Cancer Therapy 期刊论文 Jin Ronghua;Liu Zhongning;Bai Yongkang;Zhou Yongsheng;Gooding J Justin;Chen Xin
15 一种基于PU/PUF微胶囊及PCL微胶囊的自修复水性涂料及其制备方法 专利 陈鑫;田雨;陈荣华
16 Fabrication of Self-Healing Hydrogels with On-Demand Antimicrobial Activity and Sustained Biomolecule Release for Infected Skin Regeneration 期刊论文 Tian Ran;Qin Xinyu;Yuan Pingyun;Lei Kai;Wang Lin;Bai Yongkang;Liu Shiyu;Chen Xin
17 Multiple-Responsive Mesoporous Silica Nanoparticles for Highly Accurate Drugs Delivery to Tumor Cells 期刊论文 Ronghua Jin;Zhongning Liu;Yongkang Bai;Yongsheng Zhou;Xin Chen
18 Effective Control of Enzyme Activity Based on a Subtle Nanoreactor: A Promising Strategy for Biomedical Applications in the Future 期刊论文 Ronghua Jin;Zhongning Liu;Yongkang Bai;Yongsheng Zhou;Xin Chen
19 A reconfigurable, self-healing and near infrared light responsive thermoset shape memory polymer 期刊论文 Yongkang Bai;Jiwen Zhang;Didi Wen;Peiwei Gong;Jiamei Liu;Junping Ju;Xin Chen
20 一种结构可控的多孔聚合物微球制备方法及其应用 专利 陈鑫;袁萍耘
21 Stimuli-Responsive Scaffold for Breast Cancer Treatment Combining Accurate Photothermal Therapy and Adipose Tissue Regeneration 期刊论文 Bai Guo;Yuan Pingyun;Cai Bolei;Qiu Xinyu;Jin Ronghua;Liu Shiyu;Li Yan;Chen Xin
22 A poly (vinyl butyral)/graphene oxide composite with NIR light-induced shape memory effect and solid-state plasticity 期刊论文 Bai Yongkang;Zhang Jiwen;Wen Didi;Gong Peiwei;Chen Xin
23 A fast water-induced shape memory polymer based on hydroxyethyl cellulose/graphene oxide composites 期刊论文 Yongkang Bai;Xin Chen
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