新城疫病毒V蛋白靶向MAVS抑制先天性免疫机制研究
31872453
2018
C1804.兽医免疫学
孙英杰
面上项目
研究员
中国农业科学院上海兽医研究所
59万元
模式识别受体;新城疫病毒;MAVS;干扰素;家禽
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Newcastle Disease Virus V Protein Degrades Mitochondrial Antiviral Signaling Protein To Inhibit Host Type I Interferon Production via E3 Ubiquitin Ligase RNF5 | 期刊论文 | Sun Yingjie;Zheng Hang;Yu Shengqing;Ding Yunlei;Wu Wei;Mao Xuming;Liao Ying;Meng Chunchun;Rehman Zaib Ur;Tan Lei;Song Cuiping;Qiu Xusheng;Wu Fengyun;Ding Chan |
| 2 | Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity | 期刊论文 | Wei Wu;Yang Qu;Shengqing Yu;Sa Wang;Yuncong Yin;Qinfang Liu;Chunchun Meng;Ying Liao;Zaib Ur Rehman;Lei Tan;Cuiping Song;Xusheng Qiu;Weiwei Liu;Chan Ding;Yingjie Sun |
| 3 | Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections | 期刊论文 | Shanhui Ren;Chan Ding;Yingjie Sun |
| 4 | ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells | 期刊论文 | Ren Shanhui;Rehman Zaib Ur;Gao Bo;Yang Zengqi;Zhou Jiyong;Meng Chunchun;Song Cuiping;Nair Venugopal;Sun Yingjie;Ding Chan |
| 5 | Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress | 期刊论文 | Shanhui Ren;Zaib Ur Rehman;Mengyu Shi;Bin Yang;Panrao Liu;Yuncong Yin;Yurong Qu;Chunchun Meng;Zengqi Yang;Xiaolong Gao;Yingjie Sun;Chan Ding |
| 6 | Goose MAVS functions in RIG-I-mediated IFN-beta signaling activation | 期刊论文 | Sun Yingjie;Mao Xuming;Zheng Hang;Wu Wei;Rehman Zaib Ur;Liao Ying;Meng Chunchun;Qiu Xusheng;Tan Lei;Song Cuiping;Xu Lei;Yu Shengqing;Ding Chan |
| 7 | 应用CRISPR/Cas9敲除HeLa细胞DDX21基因对新城疫病毒复制的影响 | 期刊论文 | 武炜;王飒;孟春春;仇旭升;廖瑛;谭磊;宋翠萍;刘炜玮;孙英杰;丁铲 |
| 8 | The Multi-Faceted Role of Autophagy During Animal Virus Infection | 期刊论文 | Hui Jiang;Xianjin Kan;Chan Ding;Yingjie Sun |
| 9 | Syncytia generated by hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus induce complete autophagy by activating AMPK-mTORC1-ULK1 signaling | 期刊论文 | Shanhui Ren;Zaib Ur Rehman;Mengyu Shi;Bin Yang;Yurong Qu;Xiao Feng Yang;Qi Shao;Chunchun Meng;Zengqi Yang;Xiaolong Gao;Yingjie Sun;Chan Ding |
| 10 | 应用G3BP1稳转细胞系监测应激状态下的应激颗粒形成 | 期刊论文 | 邵琪;屈阳;朱子晨;孟春春;仇旭升;廖瑛;谭磊;宋翠萍;刘炜玮;孙英杰;丁铲 |
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