血管平滑肌细胞氯通道在高血压发展过程中的变化及药物作用的研究

30730105
2007
H3502.心脑血管药物药理
关永源
重点项目
教授
中山大学
170万元
细胞凋亡;氯离子通道;脑血管重构;细胞增殖;高血压
2008-01-01到2011-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ginsenoside-Rd, a new voltage-independent Ca(2+) entry blocker, reverses basilar hypertrophic remodeling in stroke-prone renovascular hypertensive rats 期刊论文 Cai, Bing-Xiang|Li, Xiao-Yan|Chen, Jing-Hui|Zhou, Jia-Guo|Wang, Guan-Lei|Guan, Yong-Yuan|Tang, Yong-Bo|Qui, Qin-Ying|
2 Effects of Tween 80 on volume-regulated chloride channel and cell proliferation in rat basilar artery smooth muscle cell 期刊论文 Tang YB|Zhou JG|Du RH|Guan YY|
3 Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel 期刊论文 Lv XF|Liu YJ|Chen JH|Zhou JG|Wang XG|Guan YY|Tang YB|
4 Volume-regulated chloride channels and cerebral vascular remodelling 期刊论文 Zhou JG|Tang YB|Guan YY|
5 Downregulation of TMEM16A calcium-activated Chloride channel contributes to cerebrovascular remodeling during Hypertension through promoting basilar smooth muscle cell proliferation 期刊论文 关永源|
6 Ginsenoside-Rd, a purified component from panax notoginseng saponins, prevents atherosclerosis in apoE knockout mice 期刊论文 Tang YB|Xie ZZ|Li J|Guan YY|Zhou JG|
7 Ginsenoside-Rd potentiates apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through the mitochondrial pathway 期刊论文 Yan-Hua Du|Yong-Yuan Guan|Xiao-Fei Lv |Xiao-Guang Wang|Yun LiuY|Jia-Guo Zhou|Ming-Ming Ma|Shi-Yang Li|Yong-Bo Tang|
8 ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway 期刊论文 Guan YY|Lv XF|Liu J|Zhou JG|Du YH|Tang YB|Qian Y|
9 Ginsenoside Rd prevents glutamate-induced apoptosis in rat cortical neurons 期刊论文 Li XY|Tang YB|Liang J| Guan YY|Zhou JG|
10 Silence of ClC-3 chloride channel inhibits cell proliferation and the cell cycle via G(1)/S phase arrest in rat basilar arterial smooth muscle cells 期刊论文 Qiu, Q. -Y.|Liu, Y. -J.|Zhou, J. -G.|Wang, G. -L.|Guan, Y. -Y.|Tang, Y. -B.|
11 Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis 期刊论文 Du YH|Tang YB|Zhou JG|Hong L|Lv XF|Xie ZZ|Tao J|Guan YY|
12 Involvement of Chk1-Cdc25A-cyclin A/CDk2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells 期刊论文 Tang, Yong-Bo|Lv, Xiao-Fei|Guan, Yong-Yuan|Kang, Xiao-Long|Zhou, Jia-Guo|Tu, Yong-Sheng|
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