蜈蚣毒素专一性Kv1.3抑制剂的药物化学及其对银屑病治疗的分子机制研究
U1302221
2013
C0403.动物生理与行为
赖仞
联合基金项目
研究员
中国科学院昆明动物研究所
210万元
多肽;钾通道;银屑病;毒素;蜈蚣
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A short peptide from frog skin accelerates diabetic wound healing | 期刊论文 | Liu Han;Duan Zilei;Tang Jing;Lv Qiumin;Rong Mingqiang;Lai Ren |
| 2 | An inhibitor peptide of toll-like receptor 2 shows therapeutic potential for allergic conjunctivitis | 期刊论文 | Xu Cheng;He Xiaoqin;Liu Weihui;Chen Yan;Zhou Chunling;Duan Zilei;Lu Qiumin;Yan Xiuwen;Zhang Zhiye;Zheng Ruiqiang |
| 3 | A bimodal activation mechanism underlies scorpion toxin-induced pain. | 期刊论文 | Yang S;Yang F;Zhang B;Lee BH;Li B;Luo L;Zheng J;Lai R |
| 4 | Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi. | 期刊论文 | Luan N;Zhou C;Li P;Ombati R;Yan X;Mo G;Rong M;Lai R;Duan Z;Zheng R |
| 5 | A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds. | 期刊论文 | 赖仞 |
| 6 | A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1 | 期刊论文 | Yang Shilong;Yang Fan;Wei Ningning;Hong Jing;Li Bowen;Luo Lei;Rong Mingqiang;Yarov-Yarovoy Vladimir;Zheng Jie;Wang KeWei;Lai Ren |
| 7 | A potential wound-healing-promoting peptide from salamander skin | 期刊论文 | Mu Lixian;Tang Jing;Liu Han;Shen Chuanbin;Rong Mingqiang;Zhang Zhiye;Lai Ren |
| 8 | 基于生物生存策略的有毒动物中药功能成分定向挖掘 | 奖励 | 赖仞 |
| 9 | 蜈蚣镇痛多肽SLP_RhTx及其基因和应用 | 专利 | 赖仞;杨仕隆 |
| 10 | Prokineticin 2 Plays a Pivotal Role in Psoriasis. | 期刊论文 | He Xiaoqin;Shen Chuanbin;Lu Qiumin;Li Jiong;Wei Yuquan;He Li;Bai Ruizhen;Zheng Jie;Luan Ning;Zhang Zhiye;Rong Mingqiang;Lai Ren |
| 11 | 姜黄素在制备治疗自身免疫疾病药物中的应用 | 专利 | 赖仞;容明强;白雪维 |
| 12 | LL-37-mtDNA复合物标志物及其应用 | 专利 | 赖仞;张治业 |
| 13 | 突出贡献奖 | 奖励 | 赖仞 |
| 14 | A novel 26RFa peptide containing both analgesic and anti-inflammatory functions from Chinese tree shrew | 期刊论文 | Zhu Yuqin;Duan Zilei;Mo Guoxiang;Shen Chuanbin;Lv Longbao;Chen Wenlin;Lai Ren |
| 15 | Mitochondrial DNA-LL-37 Complex Promotes Atherosclerosis by Escaping from Autophagic Recognition | 期刊论文 | Zhang Zhiye;Peng Ping;Han Yajun;Shen Chuanbing;Li Bowen;Hakim Ma;Zhang Xuguang;Lu Qiumin;Rong Mingqiang;Lai Ren |
| 16 | Curcumin shows excellent therapeutic effect on psoriasis in mouse model. | 期刊论文 | Kang Di;Li Bowen;Luo Lei;Jiang Wenbing;Lu Qiumin;Rong Mingqing;Lai Ren |
| 17 | Vascular endothelial growth factor from Trimeresurus jerdonii venom specifically binds to VEGFR-2 | 期刊论文 | Zhong Shurong;Wu Jianbo;Cui Yunpeng;Li Rui;Zhu Shaowen;Rong Mingqiang;Lu Qiumin;Lai Ren |
| 18 | 一种小分子多肽LZ1的应用 | 专利 | 赖仞;张治业;韩亚君 |
| 19 | A Novel Toxin from Haplopelma lividum Selectively Inhibits the Na(V)1.8 Channel and Possesses Potent Analgesic Efficacy | 期刊论文 | Meng Ping;Huang Honggang;Wang Gan;Yang Shilong;Lu Qiuming;Liu Jingze;Lai Ren;Rong Mingqiang |
| 20 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. | 期刊论文 | Jin Lin;Bai Xuewei;Luan Ning;Yao Huimin;Zhang Zhiye;Liu Weihui;Chen Yan;Yan Xiuwen;Rong Mingqiang;Lai Ren;Lu Qiumin |
| 21 | YY-39, a tick anti-thrombosis peptide containing RGD domain | 期刊论文 | Tang Jing;Fang Yaqun;Han Yajun;Bai Xuewei;Yan Xiuwen;Zhang Yun;Lai Ren;Zhang Zhiye |
| 22 | An insecticidal toxin from Nephila clavata spider venom | 期刊论文 | Jin Lin;Fang Mingqian;Chen Mengrou;Zhou Chunling;Ombati Rose;Hakim Md Abdul;Mo Guoxiang;Lai Ren;Yan Xiuwen;Wang Yumin;Yang Shilong |
| 23 | 全国创新争先奖状 | 奖励 | 赖仞 |
| 24 | Centipedes subdue giant prey by blocking KCNQ channels | 期刊论文 | Lei Luo;Bowen Li;Sheng Wang;Fangming Wu;Xiaochen Wang;Ping Liang;Rose Ombati;Junji Chen;Xiancui Lu;Jianmin Cui;Qiumin Lu;Longhua Zhang;Ming Zhou;Changlin Tian;Shilong Yang;Ren Lai |
查看更多信息请先登录或注册
