环境化学污染物诱导人体细胞转化的表观遗传机制
30630055
2006
H3001.环境卫生
陈雯
重点项目
教授
中山大学
145万元
分子标记物;细胞转化;表遗传;化学致癌物;DNA甲基化
2007-01-01到2010-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Development of human cell models for assessing the carcinogenic potential of chemicals | 期刊论文 | Li, Wenxue|Wang, Qing|Lai, Yandong|Yang, Ping|Chen, Liping|Zhuang, Zhixiong|Xiao, Yongmei|Ji, Weidong|Lin, Yuchun|Pang, Yaqin|Ma, Rulin|Zheng, Yuxin|Li, Daochuan|Wei, Qing|Tang, Shifu|Chen, Wen| |
| 2 | Comparison of global DNA methylation profiles in replicative versus premature senescence | 期刊论文 | Chen, Wen|Zhang, Wenjuan|Yang, Jianping|Zhuang, Zhixiong|Yang, Linqing|Ji, Weidong| |
| 3 | 慢病毒介导的RNA干扰技术建立hPARP-1缺陷细胞株 | 期刊论文 | 张文娟|陶恭华|纪卫东|马儒林|庄志雄|龚春梅|杨淋清|陈雯| |
| 4 | H2AX 磷酸化在 DNA 损伤修复和肿瘤中的作用 | 期刊论文 | 陈丽萍|陈雯|朱小年| |
| 5 | 基于毒性通路的毒理学危险度评价方法 | 期刊论文 | 张波|杨萍|陈雯| |
| 6 | A Novel GSK-3 beta-C/EBP alpha-miR-122-Insulin-Like Growth Factor 1 Receptor Regulatory Circuitry in Human Hepatocellular Carcinoma | 期刊论文 | Lin, Xue-Jia|Zeng, Chunxian|Yuan, Yunfei|Wang, Qing|Zhuang, Shi-Mei|Wang, Ruizhi|Li, Daochuan|Wei, Qing-Kun|Chen, Wen| |
| 7 | 蛋白磷酸酶2A及其在细胞转化中的作用 | 期刊论文 | 赖延东|陈雯| |
| 8 | Epigenetic Enhancement of p66Shc During Cellular Replicative or Premature Senescence | 期刊论文 | Yang LQ|Zhang WJ|Zhuang ZX|Xu YL|Ji WD|Yang JP| |
| 9 | Effect of PARP-1 deficiency on DNA damage and repair in human bronchial epithelial cells exposed to Benzo(a)pyrene | 期刊论文 | Yuan, Jian-hui|Liu, Jian-dong|Gong, Chun-mei|Yang, Lin-qing|Tao, Gong-hua|Liu, Jian-jun|Chen, Wen|Huang, Hai-yan|Zhuang, Zhi-xiong| |
| 10 | a4 is highly expressed in carcinogen-transformed human cells and primary human cancers | 期刊论文 | C-X Liu|J Zhao|Y-D Lai|Y-M Xiao|S-X Zhang|Y-C Lin|Q Wang|Y Zhang|L-P Chen|X-D Li|W Zhu|J-L Zeng|W Chen|Z-X Zhuang| X-W Zeng|X-M Xing|Z-F Li|X-N Zhu|B Zhang|P Yang|D-C Li|W-X Li|Z-N Lin| |
| 11 | 化学致癌物诱导人胚肾上皮细胞转化模型的构建 | 期刊论文 | 庞雅琴|陈丽萍|张波|陈雯|李道传|肖勇梅|王庆|赖延东|唐石伏|杨萍| |
| 12 | Epigenetic silencing of O-6-methylguanine DNA methyltransferase gene in NiS-transformed cells | 期刊论文 | Chen, Wen|Yu, Lei|Yuan, Jianhui|Yang, Linqing|Lu, Jiachun|Hu, Dalin|Fu, Juan|Chen, Jiakun|Pang, Yaqin|Yang, Jianping|Ji, Weidong|Li, Wenxue|Lin, Zhongning|Zhang, Wenjuan|Zhuang, Zhixiong| |
| 13 | 代谢活化系统在人细胞转化模型中的应用 | 期刊论文 | 李道传|李文学|陈雯|黄耀南|庞雅琴|陈丽萍|魏青|肖勇梅| |
| 14 | 癌基因高表达人上皮细胞转化模型的构建及应用 | 期刊论文 | 庞雅琴|李文学|林育纯|王庆|林忠宁|陈雯|李道传|杨萍|马儒林|魏青|唐石伏|肖勇梅|赖延东|陈丽萍| |
| 15 | 毒作用模式在毒理学危险度评价中的研究进展 | 期刊论文 | 张世鑫|邢秀梅|陈雯| |
| 16 | The tumor suppressor PP2A A beta regulates the RaIA GTPase | 期刊论文 | Chen, Wen|Hector, Melissa|Sablina, Anna A.|Bulmer, Sara E.|DeCaprio, James A.|Arroyo, Jason D.|Corral, Laura|Hahn, William C.| |
| 17 | 代谢活化增强苯并(a)芘诱导人上皮细胞转化效应 | 期刊论文 | 杨燕|杨萍|陈丽萍|李道传|魏青|马儒林|肖勇梅|庞雅琴|林育纯|唐石伏|王庆|陈雯|赖延东|李文学| |
| 18 | Biomarkers measured by cytokinesis-block micronucleus cytome assay for evaluating genetic damages induced by polycyclic aromatic hydrocarbons | 期刊论文 | Bin, Ping|Liu, Qingjun|Chen, Wen|Pan, Zufei|Leng, Shuguang|Duan, Huawei|Niu, Yong|Huang, Chuanfeng|Wang, Yadong|Dai, Yufei|Zheng, Yuxin| |
| 19 | microRNA 的表观遗传学调控与肿瘤 | 期刊论文 | 陈雯|李道传| |
| 20 | 细胞转化模型的建立和应用 | 期刊论文 | 陈雯| |
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