荷瘤小鼠外周血中G-MDSC获得免疫抑制功能的机制研究

31870888
2018
C0805.肿瘤免疫微环境
曾宪录
面上项目
教授
东北师范大学
58万元
信号通路;肿瘤微环境;髓系抑制性细胞;粒样髓源抑制细胞;免疫抑制功能
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 RNF8 promotes efficient DSB repair by inhibiting the pro‐apoptotic activity of p53 through regulating the function of Tip60 期刊论文 Hongyu Chen;Jin Shan;Jialing Liu;Yunpeng Feng;Yueshuang Ke;Wenjing Qi;Wenguang Liu;Xianlu Zeng
2 CXCL10 conditions alveolar macrophages within the premetastatic niche to promote metastasis 期刊论文 Chao Shang;Yingying Sun;Yawei Wang;Huifang Shi;Xiaoqing Han;Yan Mo;Dake Wang;Yueshuang Ke;Xianlu Zeng
3 CXC chemokine ligand‐10 promotes the accumulation of monocyte‐like myeloid‐derived suppressor cells by activating p38 MAPK signaling under tumor conditions 期刊论文 Yingying Sun;Yan Mo;Shu Jiang;Chao Shang;Yunpeng Feng;Xianlu Zeng
4 Lung resided monocytic myeloid-derived suppressor cells contribute to premetastatic niche formation by enhancing MMP-9 expression 期刊论文 Juechao Zhang;Xiaoqing Han;Huifang Shi;Yanyan Gao;Xuan Qiao;Huihan Li;Min Wei;Xianlu Zeng
5 MiR-449c mediates the generation of mo-MDSCs by targeting STAT6 期刊论文 Xiaoqing Han;Tao Luan;Yingying Sun;Wenyi Yan;Dake Wang;Xianlu Zeng
6 Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer 期刊论文 Yawei Wang;Yingying Sun;Chao Shang;Lili Chen;Hongyu Chen;Dake Wang;Xianlu Zeng
7 一种人体外周血中单核样髓源免疫抑制细胞的检测方法 专利 曾宪录;金贵花
8 CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3 期刊论文 Xiaoqing Han;Huifang Shi;Yingying Sun;Chao Shang;Tao Luan;Dake Wang;Xueqing Ba;Xianlu Zeng
9 Propionate and Butyrate Produced by Gut Microbiota after Probiotic Supplementation Attenuates Mouse Melanoma Cell Lung Metastasis 期刊论文 Lili Chen;Xinyu Zhou;Yawei Wang;Dake Wang;Yueshuang Ke;Xianlu Zeng
10 The downregulation of type I IFN signaling in G-MDSCs under tumor conditions promotes their development towards an immunosuppressive phenotype 期刊论文 Yingying Sun;Xiaoqing Han;Chao Shang;Yawei Wang;Boya Xu;Shu Jiang;Yan Mo;Dake Wang;Yueshuang Ke;Xianlu Zeng
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