LncRNA-ANCR介导的组蛋白甲基化酶EZH2稳定性在乳腺癌转移中的作用和机制
31571317
2015
C0601.遗传物质结构与功能
陆军
面上项目
教授
东北师范大学
65万元
乳腺癌转移;上皮-间质转化;表观遗传调控;蛋白稳定性;长链非编码RNA-ANCR
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The interplay between p16 serine phosphorylation and arginine methylation determines its function in modulating cellular apoptosis and senescence | 期刊论文 | Lu Yang;Ma Wenlong;Li Zhongwei;Lu Jun;Wang Xiuli |
| 2 | Muscle-Specific Histone H3K36 Dimethyltransferase SET-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression. | 期刊论文 | Su Liangping;Li Hongyuan;Huang Cheng;Zhao Tingting;Zhang Yongjun;Ba Xueqing;Li Zhongwei;Zhang Yu;Huang Baiqu;Lu Jun;Zhao Yanmei;Li Xiaoxue |
| 3 | Methylation of arginine by PRMT1 regulates Nrf2 transcriptional activity during the antioxidative response | 期刊论文 | Liu Xin;Li Hongyuan;Liu Lingxia;Lu Yang;Gao Yanyan;Geng Pengyu;Li Xiaoxue;Huang Baiqu;Zhang Yu;Lu Jun |
| 4 | Arginine methylation of SKN-1 promotes oxidative stress resistance in Caenorhabditis elegans | 期刊论文 | Li Hongyuan;Su Liangping;Su Xin;Liu Xin;Wang Dan;Li Hongmei;Ba Xueqing;Zhang Yu;Lu Jun;Huang Baiqu;Li Xiaoxue |
| 5 | The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer. | 期刊论文 | Li Zhongwei;Hou Pingfu;Fan Dongmei;Dong Meichen;Ma Musong;Li Hongyuan;Yao Ruosi;Li Yuxin;Wang Guannan;Geng Pengyu;Mihretab Adhanom;Liu Dongxu;Zhang Yu;Huang Baiqu;Lu Jun |
| 6 | Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer | 期刊论文 | Feng Jingxin;Xu Guiying;Liu Jiwei;Zhang Na;Li Lili;Ji Jiafei;Zhang Jianchao;Zhang Lian;Wang Guannan;Wang Xiuli;Tan Jiang;Huang Baiqu;Lu Jun;Zhang Yu |
| 7 | 细胞恶性转化的表观遗传学机制研究 | 奖励 | 陆军;张瑜;姚若斯;张建超;赵 黎;侯平甫;杜 娟;孔晨飞;董智雄;黄百渠 |
| 8 | Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms. | 期刊论文 | Feng J;Li L;Zhang N;Liu J;Zhang L;Gao H;Wang G;Li Y;Zhang Y;Li X;Liu D;Lu J;Huang B |
| 9 | The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1 | 期刊论文 | Gao Yanyan;Zhao Yaping;Zhang Juechao;Lu Yang;Liu Xin;Geng Pengyu;Huang Baiqu;Zhang Yu;Lu Jun |
| 10 | LncRNA ANCR down-regulation promotes TGF-beta-induced EMT and metastasis in breast cancer | 期刊论文 | Li Zhongwei;Dong Meichen;Fan Dongmei;Hou Pingfu;Li Hongyuan;Liu Lingxia;Lin Cong;Liu Jiwei;Su Liangping;Wu Lan;Li Xiaoxue;Huang Baiqu;Lu Jun;Zhang Yu |
| 11 | 蛋白质精氨酸甲基转移酶7在癌细胞转移中的应用 | 专利 | 陆军;张瑜;姚若斯;姜浩;李晓雪;黄百渠 |
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