抗凋亡蛋白(Bcl-2)/人血清白蛋白与抗肿瘤无机药物复合物的结构和功能

31460232
2014
C0508.无机生物化学与环境测控
杨峰
地区科学基金项目
教授
广西师范大学
50万元
抗凋亡蛋白;抗肿瘤无机药物;蛋白-配体相互作用;蛋白质结构;人血清白蛋白
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain. 期刊论文 Qi J;Gou Y;Zhang Y;Yang K;Chen S;Liu L;Wu X;Wang T;Zhang W;杨峰
2 Folate-functionalized human serum albumin carrier for anticancer copper(II) complexes derived from natural plumbagin 期刊论文 Gou Yi;Zhang Zhan;Qi Jinxu;Liang Shichu;Zhou Zuping;杨峰;Liang Hong
3 Structure and biological properties of mixed-ligand Cu(II) Schiff base complexes as potential anticancer agents 期刊论文 Gou Y;Li J;Fan B;Xu B;Zhou M;杨峰
4 Designing anticancer multitarget metal thiosemicarbazone prodrug based on the nature of binding sites of human serum albumin carrier 期刊论文 Feng Yang;Hong Liang
5 广西“十百千人才工程”第二层次人选 奖励 杨峰
6 HSA-based multi-target combination therapy: regulating drugs' release from HSA and overcoming single drug resistance in a breast cancer model 期刊论文 Gou Y;Zhang Z;Li D;Zhao L;Cai M;Zhang Y;Sun H;Wang T;Liang H;杨峰
7 Enhancing the copper(II) complexes cytotoxicity to cancer cells through bound to human serum albumin 期刊论文 Gou Y;Zhang Y;Qi J;Zhou Z;杨峰;Liang H
8 Developing an Anticancer Copper(II) Pro-Drug Based on the His242 Residue of the Human Serum Albumin Carrier IIA Subdomain 期刊论文 Qi Jinxu;Zhang Yao;Gou Yi;Zhang Zhenlei;Zhou Zuping;Wu Xiaoyang;杨峰;Liang Hong
9 人血清白蛋白-药物复合物及其合成方法和应用 专利 杨峰;张振雷;齐金旭;苟峄;张耀;王俊
10 Four copper(II) compounds synthesized by anion regulation: structure, anticancer function and anticancer mechanism. 期刊论文 Zhang Z;Gou Y;Wang J;Yang K;Qi J;Zhou Z;Liang S;Liang H;杨峰
11 HSA IIA subdomain-based developing anticancer metal pro-drug: a new and improved approach 期刊论文 杨峰;Liang H
12 Structural basis and anticancer properties of ruthenium-based drugcomplexed with human serum albumin 期刊论文 Zhang Y;Ho A;Yue J;Kong L;Zhou Z;Wu X;杨峰;Liang H
13 In Vivo Epidermal Migration Requires Focal Adhesion Targeting of ACF7 期刊论文 Yue JP;Zhang Y;Liang WG;Gou XW;Lee P;Liu H;Lyu WQ;Tang WJ;Chen SY;杨峰;Liang H;Wu XY
14 Developing anticancer copper(II) prodrugs basedon the nature of cancer cells and human serum albumin carrier IIA subdomain 期刊论文 Gou Y;Qi J;Ajayi JP;Zhang Y;Zhou Z;Wu X;杨峰;H Liang
15 Synthesis of four binuclear copper(II)complexes: structure, anticancer properties and anticancer mechanism 期刊论文 Qi J;Liang S;Gou Y;Zhang Z;Zhou Z;杨峰;Liang H
16 一种铜金属配合物及其与人血清白蛋白的复合物以及它们的合成方法及应用 专利 杨峰;梁宏;齐金旭
17 Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin 期刊论文 Jun Wang;Yi Gou;Zhenlei Zhang;Ping Yu;Jinxu Qi;Qipin Qin;Hongbin Sun;Xiaoyang Wu;Hong Liang;Feng Yang
18 Binding and Anticancer Properties of Plumbagin withHuman Serum Albumin 期刊论文 Gou Y;Zhang Y;Qi J;Kong L;Zhou Z;Liang S;杨峰;Liang H
19 ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics. 期刊论文 Ma YL;Yue JP;Zhang Y;Shi CZ;Odenwald M;Liang WG;Gou XW;Liu Y;Chen SY;Tang WJ;Turner J;Liang H;杨峰;Qin HL;Wu XY
20 Designing Prodrugs Based on Special Residues of Human Serum Albumin 期刊论文 Gou Yi;杨峰;Liang Hong
21 Designing anticancer copper(II) complexes by optimizing 2-pyridinethiosemicarbazone ligands 期刊论文 Jungang Deng;Ping Yu;Zhenlei Zhang;Jun Wang;Jinhua Cai;Na Wu;Hongbin Sun;Hong Liang;Feng Yang
22 α-N-heterocyclic thiosemicarbazone Fe(III) complex: Characterization of its antitumor activity and identification of anticancer mechanism. 期刊论文 Gou Y;Wang J;Chen S;Zhang Z;Zhang Y;Zhang W;杨峰
23 Design of an Anticancer Copper(II) Prodrug Based on the Lys199 Residue of the Active Targeting Human Serum Albumin Nanoparticle Carrier 期刊论文 Gou Y;Zhang Y;Zhang Z;Wang J;Zhou Z;Liang H;杨峰
24 Structural basis of non-steroidalanti-inflammatory drug diclofenac binding to human serum albumin 期刊论文 Zhang Y;Lee P;Liang S;Zhou Z;Wu X;杨峰;Liang H
25 Evaluation of interactions betweenplatinum-/ruthenium-based anticancer agents and human serum albumin:Development of HSA carrier for metal-based drugs. 期刊论文 Gou Y;Zhang Y;杨峰;Liang H
26 Developing an anticancer copper(II) pro-drug based on the nature of cancer cell and human serum albumin carrier IIA subdomain: mouse model of breast cancer 期刊论文 Gou Yi;Zhang Yao;Qi Jinxu;Chen Shifang;Zhou Zuping;Wu Xiaoyang;Liang Hong;杨峰
27 基于DNA、蛋白质靶标新型抗肿瘤活性化合物的发现 奖励 杨峰
28 Multidrug Delivery Systems Based on Human Serum Albumin for Combination Therapy with Three Anticancer Agents 期刊论文 Qi Jinxu;Zhang Yao;Gou Yi;Lee Philbert;Wang Jun;Chen Shifang;Zhou Zuping;Wu Xiaoyang;杨峰;Liang Hong
29 Design an anticancer copper(II) pro-drug based on the flexible IIA subdomain of human serum albumin. 期刊论文 Zhang Y;Zhang ZL;Gou Y;Jiang M;Khan H;Zhou ZP;Liang H;杨峰
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