基于肿瘤新生血管靶向的多肽自组装纳米药物的设计和机制研究

31300822
2013
C1008.生物与医学工程新技术新方法
丁艳萍
青年科学基金项目
副研究员
国家纳米科学中心
20万元
多肽;血管新生;纳米颗粒;自组装;肿瘤
2014-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 "Triple-punch" strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy. 期刊论文 Tianjiao Ji|Meiyu Wu|Yan Wu|Guangjun Nie|
2 Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases. 期刊论文 Yinlong Zhang|Xiao Zhao|Gregory J. Anderson|Guangjun Nie|
3 Precision combination therapy for triple negative breast cancer via biomimetic polydopamine polymer core-shell nanostructures. 期刊论文 Long Chen|Qun Yu|Yan Wu|Guangjun Nie|
4 Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy. 期刊论文 Ruifang Zhao|Jingyan Wei|Sheng Qi|Guangjun Nie|
5 Integration of photothermal therapy and synergistic chemotherapy by a porphyrin self-assembled micelle confers chemosensitivity in triple-negative breast cancer 期刊论文 Yanping Ding|Yiye Li|Yan Wu|Guangjun Nie|
6 Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-Associated Fibroblast Activation 期刊论文 Ning Tao|Zhihai Qin|Guangjun Nie|Yuliang Zhao|
7 Peptide assembly integration of fibroblast-targeting and cell-penetration features for enhanced antitumor drug delivery 期刊论文 Jian Shi|Ning Tao|Zhihai Qin|Guangjun Nie|
8 Improvement of Stability and Efficacy of C16Y Therapeutic Peptide via Molecular Self-Assembly into Tumor-Responsive Nanoformulation 期刊论文 Xiao Zhao|Jian Shi|Saraswati Sukumar|Guangjun Nie|
9 "Triple-punch" strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy. 期刊论文 Tianjiao Ji|Meiyu Wu|Yan Wu|Guangjun Nie|
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