整合机器学习方法和多源异构特征筛选分析单氨基酸多态性对蛋白质的功能影响

61303169
2013
F0213.生物信息计算与数字健康
王明君
青年科学基金项目
助理研究员
中国科学院天津工业生物技术研究所
22万元
疾病相关;生物信息学;特征选择;机器学习;单氨基酸多态性
2014-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 SOHPRED: a new bioinformatics tool for the characterization and prediction of human S-sulfenylation sites 期刊论文 Wang, Xiaofeng|Yan, Renxiang|Li, Jinyan|Song, Jiangning|
2 Identification of WD40 repeats by secondary structure-aided profile-profile alignment 期刊论文 Su, Xiao-Dong|Zhang, Ziding|Li, Jinyan|Song, Jiangning|
3 KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins 期刊论文 Li, Chen|Androulakis, Steve|Buckle, Ashley M.|Song, Jiangning|
4 GlycoMine(struct): a new bioinformatics tool for highly accurate mapping of the human N-linked and O-linked glycoproteomes by incorporating structural features 期刊论文 Webb, Geoffrey I.|Li, Jian|Song, Jiangning|Lithgow, Trevor|
5 Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets 期刊论文 Tan, Hao|Akutsu, Tatsuya|Whisstock, James C.|Song, Jiangning|
6 Crysalis: an integrated server for computational analysis and design of protein crystallization 期刊论文 Zhang, Ziding|Webb, Geoffrey I.|Lin, Donghai|Song, Jiangning|
7 Periscope: quantitative prediction of soluble protein expression in the periplasm of Escherichia coli 期刊论文 Webb, Geoffrey I.|Tey, BengTi|Song, Jiangning|Ramanan, Ramakrishnan Nagasundara|
8 Computational characterization of parallel dimeric and trimeric coiled-coils using effective amino acid indices 期刊论文 Wang, Xiao-Feng|Chen, Zhen|Zhang, Ziding|Song, Jiangning|
9 Accurate in silico identification of species-specific acetylation sites by integrating protein sequence-derived and functional features 期刊论文 Tan, Hao|Zhang, Ziding|Webb, Geoffrey I.|Song, Jiangning|
10 A neural network learning approach for improving the prediction of residue depth based on sequence-derived features 期刊论文 Cai, Weiwen|Lin, Juan|Li, Jian|Song, Jiangning|
11 GlycoMine: a machine learning-based approach for predicting N-, C- and O-linked glycosylation in the human proteome 期刊论文 Webb, Geoffrey I.|Zhang, Yang|Whisstock, James C.|Song, Jiangning|
12 Towards more accurate prediction of protein folding rates: a review of the existing web-based bioinformatics approaches 期刊论文 Chang, Catherine Ching Han|Tey, Beng Ti|Song, Jiangning|Ramanan, Ramakrishnan Nagasundara|
13 DephosSite: a machine learning approach for discovering phosphotase-specific dephosphorylation sites 期刊论文 Wang, Xiaofeng|Yan, Renxiang|Song, Jiangning|
14 PredPPCrys: Accurate Prediction of Sequence Cloning, Protein Production, Purification and Crystallization Propensity from Protein Sequences Using Multi-Step Heterogeneous Feature Fusion and Selection 期刊论文 Tan, Hao|Li, Yuan|Zhang, Ziding|Song, Jiangning|
15 Towards more accurate prediction of ubiquitination sites: a comprehensive review of current methods, tools and features 期刊论文 Chen, Zhen|Zhou, Yuan|Zhang, Ziding|Song, Jiangning|
16 SPAR: a random forest-based predictor for self-interacting proteins with fine-grained domain information 期刊论文 Yang, Shiping|Li, Chen|Zhang, Ziding|Song, Jiangning|
17 Towards more accurate prediction of ubiquitination sites: a comprehensive review of current methods, tools and features 期刊论文 Chen, Zhen|Zhou, Yuan|Zhang, Ziding|Song, Jiangning|
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