谷氨酸棒杆菌的甲醇利用限制因素研究
31700044
2017
C0103.微生物组学与代谢
王钰
青年科学基金项目
研究员
中国科学院天津工业生物技术研究所
25万元
碳源;途径组装;适应性进化;甲醇;代谢机制
2018-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Adaptive laboratory evolution enhances methanol tolerance and conversion in engineered Corynebacterium glutamicum | 期刊论文 | Wang Yu;Fan Liwen;Tuyishime Philibert;Liu Jiao;Zhang Kun;Gao Ning;Zhang Zhihui;Ni Xiaomeng;Feng Jinhui;Yuan Qianqian;Ma Hongwu;Zheng Ping;Sun Jibin;Ma Yanhe |
| 2 | A novel Corynebacterium glutamicum L-glutamate exporter | 期刊论文 | Wang Yu;Cao Guoqiang;Xu Deyu;Fan Liwen;Wu Xinyang;Ni Xiaomeng;Zhao Shuxin;Zheng Ping;Sun Jibin;Ma Yanhe |
| 3 | 一碳代谢关键酶——甲醇脱氢酶的研究进展与展望 | 期刊论文 | 凡立稳;王钰;郑平;孙际宾 |
| 4 | Expanding targeting scope, editing window, and base transition capability of base editing in Corynebacterium glutamicum | 期刊论文 | Wang Yu;Liu Ye;Li Junwei;Yang Yi;Ni Xiaomeng;Cheng Haijiao;Huang Teng;Guo Yanmei;Ma Hongwu;Zheng Ping;Wang Meng;Sun Jibin;Ma Yanhe |
| 5 | 一种提高菌株的甲醇生物耐受性和生物转化效率的方法 | 专利 | 孙际宾;王钰;郑平;凡立稳;周文娟;马延和 |
| 6 | 一种提高微生物对甲醇的耐受性和利用率的方法 | 专利 | 孙际宾;王钰;郑平;凡立稳;周文娟;马延和 |
| 7 | Synthetic methylotrophy: a practical solution for methanol-based biomanufacturing | 期刊论文 | Wang Yu;Fan Liwen;Tuyishime Philibert;Zheng Ping;Sun Jibin |
| 8 | MACBETH: Multiplex automated Corynebacterium glutamicum base editing method | 期刊论文 | Wang Yu;Liu Ye;Liu Jiao;Guo Yanmei;Fan Liwen;Ni Xiaomeng;Zheng Xiaomei;Wang Meng;Zheng Ping;Sun Jibin;Ma Yanhe |
| 9 | Engineering Corynebacterium glutamicum for methanol-dependent growth and glutamate production | 期刊论文 | Tuyishime Philibert;Wang Yu;Fan Liwen;Zhang Qiongqiong;Li Qinggang;Zheng Ping;Sun Jibin;Ma Yanhe |
| 10 | 甲醇生物转化菌株的构建方法及构建的菌株和应用 | 专利 | 郑平;王钰;孙际宾;凡立稳;T.菲利伯特;马延和 |
| 11 | Mutations on peptidoglycan synthesis gene ponA improve electro-transformation efficiency of Corynebacterium glutamicum ATCC 13869 | 期刊论文 | Liu Jiao;Wang Yu;Lu Yujiao;Ni Xiaomeng;Guo Xuan;Zhao Jing;Chen Jiuzhou;Dele-Osibanjo Taiwo;Zheng Ping;Sun Jibin;Ma Yanhe |
| 12 | Engineering artificial fusion proteins for enhanced methanol bioconversion | 期刊论文 | Fan Liwen;Wang Yu;Tuyishime Philibert;Gao Ning;Li Qinggang;Zheng Ping;Sun Jibin;Ma Yanhe |
| 13 | CRISPR/Cas9-mediated ssDNA recombineering in Corynebacterium glutamicum | 期刊论文 | Liu Jiao;Wang Yu;Zheng Ping;Sun Jibin |
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