以特异组蛋白H3K4me3修饰作为卵子老化及卵巢退行性变化的生物标记物和评价指标的研究

91949108
2019
C1206.生殖细胞及性别决定
沙倩倩
重大研究计划
研究员
广东省第二人民医院
68万元
排卵;卵母细胞成熟;小鼠;组蛋白修饰;卵巢功能低下
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation 期刊论文 Rong Yan;Zhu Ye-Zhang;Yu Jia-Li;Wu Yun-Wen;Ji Shu-Yan;Zhou Yong;Jiang Yu;Jin Jin;Fan Heng-Yu;Shen Li;Sha Qian-Qian
2 Function and Regulation of Histone H3 Lysine-4 Methylation During Oocyte Meiosis and Maternal-to-Zygotic Transition 期刊论文 Sha Qian-Qian;Zhang Jue;Fan Heng-Yu
3 Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans 期刊论文 Sha Qian-Qian;Zheng Wei;Wu Yun-Wen;Li Sen;Guo Lei;Zhang Shuo-Ping;Lin Ge;Ou Xiang-Hong;Fan Heng-Yu
4 Role of CxxC-finger protein 1 in establishing mouse oocyte epigenetic landscapes 期刊论文 Sha Qian-Qian;Zhu Ye-Zhang;Xiang Yun-Long;Yu Jia-Li;Fan Xiao-Ying;Li Yan-Chu;Wu Yun-Wen;Shen Li;Fan Heng-Yu
5 Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging 期刊论文 Wu Yun-Wen;Li Sen;Zheng Wei;Li Yan-Chu;Chen Lu;Zhou Yong;Deng Zuo-Qi;Lin Ge;Fan Heng-Yu;Sha Qian-Qian
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