迷走神经调控哮喘肺部区域免疫的特点和机制

91942305
2019
H0104.支气管哮喘
苏枭
重大研究计划
研究员
中国科学院上海巴斯德研究所
250万元
迷走神经;神经肽;肺区域免疫;哮喘;外泌体
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Vagal α7nAChR signaling regulates α7nAChR+Sca1+ cells during lung injury repair 期刊论文 Xiaoyan Chen;Jie Chen;Yuanlin Song;Xiao Su
2 SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection 期刊论文 Li Ling;Wu Haiya;Li Qingmei;Chen Jie;Xu Kaifeng;Xu Jinfu;Su Xiao
3 Vagal-α7nAChR signaling attenuates allergic asthma responses and facilitates asthma tolerance by regulating inflammatory group 2 innate lymphoid cells 期刊论文 Xintong Feng;Ling Li;Wei He;Na Li;Tianyun Shi;Zhijun Jie;Xiao Su
4 Vagal-α7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair 期刊论文 Xiaoyan Chen;Caiqi Zhao;Cuiping Zhang;Qingmei Li;Jie Chen;Lianping Cheng;Jian Zhou;Xiao Su;Yuanlin Song
5 Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages 期刊论文 Cuiping Zhang;Caiqi Zhao;Xiaoyan Chen;Rujia Tao;Sijiao Wang;Guangxun Meng;Xing Liu;Changzhou Shao;Xiao Su
6 Activation of α7 nicotinic acetylcholine receptor promotes HIV-1 transcription 期刊论文 Wen Jing;Zhao Caiqi;Song Shuting;Lin Zhekai;Xie Sitao;Qi Huaxin;Wang Jianhua;Su Xiao
7 iNKT cells with high PLZF expression are recruited into the lung via CCL21‐CCR7 signaling to facilitate the development of asthma tolerance in mice 期刊论文 Xintong Feng;Caiqi Zhao;Ling Li;Jingjing Feng;Wei He;Tianyun Shi;Na Li;Zhijun Jie;Xiao Su
8 Deficiency of HIF-1 alpha enhances influenza A virus replication by promoting autophagy in alveolar type II epithelial cells 期刊论文 Zhao Caiqi;Chen Jie;Cheng Lianping;Xu Kaifeng;Yang Yiyu;Su Xiao
9 急性呼吸窘迫综合征致病新机制和诊疗新技术及推广 奖励 苏枭
10 PLZF promotes the development of asthma tolerance via affecting memory phenotypes of immune cells 期刊论文 Na Li;Tianyun Shi;Meng Zhang;Yanchao He;Jingjing Feng;Zhoufang Mei;Xiao Su;Zhijun Jie
11 Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection 期刊论文 Zhaowei Gao;Ling Li;Yuanyuan Huang;Caiqi Zhao;Shuangjia Xue;Jie Chen;Zhongzhou Yang;Jinfu Xu;Xiao Su
12 Cholinergic-α7 nAChR signaling suppresses SARS-CoV-2 infection and inflammation in the lung epithelial cells 期刊论文 Jing Wen;Jing Sun;Yangong Tang;Jincun Zhao;Xiao Su
13 Increased airway epithelial cell-derived exosomes activate macrophage-mediated allergic inflammation via CD100 shedding 期刊论文 Yu Yi;Zhou Yao;Di Caixia;Zhao Caiqi;Chen Jie;Su Wen;Wu Qun;Wu Min;Su Xiao;Xia Zhenwei
14 Oral antibiotics relieve allergic asthma in post-weaning mice via reducing iNKT cells and function of ADRB2 期刊论文 Na Li;Jia Chen;Sitao Xie;Meng Zhang;Tianyun Shi;Yanchao He;Zhijun Jie;Xiao Su
15 Hemin-primed dendritic cells suppress allergic airway inflammation through releasing extracellular vesicles. 期刊论文 Wu Yujiao;Yu Qianying;Zhang Meng;Zhou Yao;Su Xiao;Wu Min;Lv Jiajia;Xia Zhenwei
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