PHF1促进乳腺癌发生发展的表观遗传调控机制的研究
81773017
2017
H1805.肿瘤表观遗传
王艳
面上项目
研究员
中国医学科学院肿瘤医院
62万元
转录调控;PHD锌指蛋白;上皮间质转化;组蛋白修饰;C21_乳腺肿瘤
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Proteomic analysis of the OGT interactome: novel links to epithelial-mesenchymal transition and metastasis of cervical cancer | 期刊论文 | Jie Gao;Yang Yang;Rongfang Qiu;Kai Zhang;Xu Teng;Ruiqiong Liu;Yan Wang |
| 2 | PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis | 期刊论文 | Yongqiang Hou;Wei Liu;Xianfu Yi;Yang Yang;Dongxue Su;Wei Huang;Hefen Yu;Xu Teng;Ying Yang;Wei Feng;Tao Zhang;Jie Gao;Kai Zhang;Rongfang Qiu;Yan Wang |
| 3 | CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway | 期刊论文 | Wei Huang;Jingyao Zhang;Miaomiao Huo;Jie Gao;Tianshu Yang;Xin Yin;Pei Wang;Shuai Leng;Dandan Feng;Yang Chen;Yang Yang;Yan Wang |
| 4 | SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis | 期刊论文 | Shuai Leng;Wei Huang;Yang Chen;Yang Yang;Dandan Feng;Wei Liu;Tianyang Gao;Yanli Ren;Miaomiao Huo;Jingyao Zhang;Yunkai Yang;Yan Wang |
| 5 | PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5–WDR77/CRL4B complex to promote tumorigenesis | 期刊论文 | Ruiqiong Liu;Jie Gao;Yang Yang;Rongfang Qiu;Yu Zheng;Wei Huang;Yi Zeng;Yongqiang Hou;Shuang Wang;Shuai Leng;Dandan Feng;Wenqian Yu;Gancheng Sun;Hang Shi;Xu Teng;Yan Wang |
| 6 | The histone deacetylase inhibitor PCI-24781 impairs calcium influx and inhibits proliferation and metastasis in breast cancer | 期刊论文 | Yang Tianshu;Wang Pei;Yin Xin;Zhang Jingyao;Huo Miaomiao;Gao Jie;Li Gen;Teng Xu;Yu Hefen;Huang Wei;Wang Yan |
| 7 | MicroRNA-455-3p Mediates GATA3 Tumor Suppression in Mammary Epithelial Cells by Inhibiting TGF-b Signaling | 期刊论文 | Yi Zeng;Tianyang Gao;Wei Huang;Yang Yang;Rongfang Qiu;Yongqiang Hou;Wenqian Yu;Shuai Leng;Dandan Feng;Wei Liu;Xu Teng;Hefen Yu;Yan Wang |
| 8 | LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer | 期刊论文 | Yang Yang;Wei Huang;Rongfang Qiu;Ruiqiong Liu;Yi Zeng;Jie Gao;Yu Zheng;Yongqiang Hou;Shuang Wang;Wenqian Yu;Shuai Leng;Dandan Feng;Yan Wang |
| 9 | GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer | 期刊论文 | Wenqian Yu;Wei Huang;Yang Yang;Rongfang Qiu;Yi Zeng;Yongqiang Hou;Gancheng Sun;Hang Shi;Shuai Leng;Dandan Feng;Yang Chen;Shuang Wang;Xu Teng;Hefen Yu;Yan Wang |
| 10 | Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition | 期刊论文 | Jie Gao;Ruiqiong Liu;Dandan Feng;Wei Huang;Miaomiao Huo;Jingyao Zhang;Shuai Leng;Yang Yang;Tianshu Yang;Xin Yin;Xu Teng;Hefen Yu;Baowen Yuan;Yan Wang |
| 11 | Role of Epigenetic Regulation in Plasticity of Tumor Immune Microenvironment | 期刊论文 | Yunkai Yang;Yan Wang |
| 12 | CRL4B复合物通过抑制SFRP1促进胰腺癌的发生发展 | 期刊论文 | 陈旸;冷帅;王艳 |
| 13 | 同源异型盒1基因促进乳腺癌细胞增殖和侵袭 | 期刊论文 | 任彦丽;冯丹丹;杨阳;黄蔚;王艳 |
| 14 | Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis | 期刊论文 | Yi Zeng;Rongfang Qiu;Yang Yang;Tianyang Gao;Yu Zheng;Wei Huang;Jie Gao;Kai Zhang;Ruiqiong Liu;Shuang Wang;Yongqiang Hou;Wenqian Yu;Shuai Leng;Dandan Feng;Wei Liu;Xi Zhang;Yan Wang |
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