甲基化DNA结合蛋白的高通量鉴定和表观遗传小分子调节剂的筛选

92053101
2020
B04.化学测量学
康经武
重大研究计划
研究员
中国科学院上海有机化学研究所
70万元
小分子调节剂;甲基化DNA结合蛋白;定量蛋白组学;表观遗传学;DNA甲基化
2021-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Profiling protein interactions by purification with capillary monolithic affinity column in combination with label-free quantitative proteomics 期刊论文 Liu Guizhen;Du Yanan;Fu Tao;Pan Lifeng;Kang Jingwu
2 Preparation of Poly (N‐vinylpyrrolidone‐co‐pentaerythritol triacrylate) monolithic column for hydrophilic interaction chromatography 期刊论文 Jing Li;Danye Qiu;Feng Li;Jingwu Kang
3 Chemoproteomics and Phosphoproteomics Profiling Reveals Salvianolic Acid A as a Covalent Inhibitor of mTORC1 期刊论文 Mengmeng Zheng;Yanmei Zhang;Yao Xu;Ying Han;Yingli Wu;Jingwu Kang
4 Comprehensive Profiling of Rapamycin Interacting Proteins with Multiple Mass Spectrometry-Based Omics Techniques 期刊论文 Yao Xu;Mengmeng Zheng;Li Gong;Guizhen Liu;Shanshan Qian;Ying Han;Jingwu Kang
5 Target proteins profiling of irreversible kinase inhibitor pelitinib and discovery of degradation of PRDX4 by label free chemoproteomics 期刊论文 Li Jing;Zheng Mengmeng;Xu Yao;Yang Xin;Kang Jingwu
6 Determination of 5-methyldeoxycytosine and oxidized derivatives by nano-liquid chromatography with zwitterionic monolithic capillary column 期刊论文 Qiu Danya;Liu Guizhen;Li Feng;Kang Jingwu
7 Coupling capillary electrophoresis-electrospray ionization mass spectrometry with sheathless interface for drug analysis 期刊论文 Hanzhi ZHANG;Feng LI;Jingwu KANG
8 Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics 期刊论文 Shanshan Qian;Ying Han;Yue Zhang;Yanan Du;Jing Li;Xin Yang;Jingwu Kang
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