生理活性物种的选择性传感与原位分析新方法研究

20935005
2009
B0404.化学与生物传感
马会民
重点项目
研究员
中国科学院化学研究所
190万元
选择性传感;生物电分析化学;原位分析;光学探针
2010-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A colorimetric sensor for determination of cysteine by carboxymethyl cellulose-functionalized gold nanoparticles 期刊论文 Wei, Xiaoyi|Qi, Li|Tan, Junjun|Liu, Ruigang|Wang, Fuyi|
2 Use of a rhodamine-based bifunctional probe in N-terminal specific labeling of Thermomyces lanuginosus xylanase 期刊论文 Jia, Jia|Chen, Wei|Ma, Huimin|Wang, Ke|Zhao, Chuan|
3 Determination of sodium benzoate by chiral ligand exchange CE based on its inhibitory activity in D-amino acid oxidase mediated oxidation of D-serine 期刊论文 Zhang, Haizhi|Qi, Li|Qiao, Juan|Mao, Lanqun|
4 Assay of vitamin B in urine by capillary electrochromatography with methacrylate-based monolithic column 期刊论文 Wei, Xiaoyi|Qi, Li|Qiao, Juan|Yao, Chunhe|Wang, Fuyi|Chen, Yi|
5 生物分子的光学探针与标记分析研究 奖励 马会民|陈传峰|李晓花|孙姝娜|史 文|张关心|胡海宇|韩彦丽|
6 基于蛋白质及手性氨基酸分析的生物色谱新方法研究 奖励 陈义|乔娟|张海枝|姚春荷|沈莹|木肖玉|张荣月|辛培勇|魏晓奕|
7 Photodecomposition of Ferrocenedicarboxylic Acid in Methanol to Form an Electroactive Infinite Coordination Polymer and Its Application in Bioelectrochemistry 期刊论文 Zhang, Li|Gao, Xia|Yang, Lifen|Yu, Ping|Mao, Lanqun|
8 A chiral ligand exchange CE system for studying the inhibitory effect of kojic acid on tyrosinase 期刊论文 B. Sun, L. Qi,* X. Y. Mu, J. Qiao, M. Wang|
9 Continuous Electrochemical Monitoring of Extracellular Lactate Production from Neonatal Rat Cardiomyocytes following Myocardial Hypoxia 期刊论文 Li, Xianchan|Zhao, Lingzhi|Chen, Zhenling|Lin, Yuqing|Yu, Ping|Mao, Lanqun|
10 A versatile method for the preparation of polyacrylamide derivative functionalized thermo-responsive gold nanoparticles 期刊论文 Qiao, Juan|Mua, Xiaoyu|Qi, Li|
11 Fluorescent carbon nanodots conjugated with folic acid for distinguishing folate-receptor-positive cancer cells from normal cells 期刊论文 Song, Yanchao|Shi, Wen|Chen, Wei|Li, Xiaohua|Ma, Huimin|
12 Preparation of porous polymer monolithic column using functionalized graphene oxide as a functional crosslinker for high performance liquid chromatography separation of small molecules 期刊论文 Li, Yaping|Qi, Li|Ma, Huimin|
13 Silver Phosphate/Carbon Nanotube-Stabilized Pickering Emulsion for Highly Efficient Photocatalysis 期刊论文 Zhai, Wanying|Li, Gaiping|Yu, Ping|Yang, Lifen|Mao, Lanqun|
14 Sensitive and selective voltammetric measurement of Hg2+ by rational covalent functionalization of graphene oxide with cysteamine 期刊论文 Zhou, Heng|Wang, Xiang|Yu, Ping|Chen, Xiaoming|Mao, Lanqun|
15 Distinguishing Folate-Receptor-Positive Cells from Folate-Receptor-Negative Cells Using a Fluorescence Off-On Nanoprobe 期刊论文 Feng, Duan|Song, Yanchao|Shi, Wen|Li, Xiaohua|Ma, Huimin|
16 A spectroscopic off-on probe for simple and sensitive detection of carboxylesterase activity and its application to cell imaging 期刊论文 Zhang, Yangyang|Chen, Wei|Feng, Duan|Shi, Wen|Li, Xiaohua|Ma, Huimin|
17 Aspartic Acid-Promoted Highly Selective and Sensitive Colorimetric Sensing of Cysteine in Rat Brain 期刊论文 Qian, Qin|Deng, Jingjing|Wang, Dalei|Yang, Lifen|Yu, Ping|Mao, Lanqun|
18 l-Lysine-derived ionic liquids as chiral ligands of Zn(II) complexes used in ligand-exchange CE 期刊论文 Zhang, Haizhi|Qi, Li|Shen, Ying|Qiao, Juan|Mao, Lanqun|
19 High-performance affinity monolith chromatography for chiral separation and determination of enzyme kinetic constants 期刊论文 Yao, Chunhe|Qi, Li|Qiao, Juan|Zhang, Haizhi|Wang, Fuyi|Chen, Yi|Yang, Gengliang|
20 Ionic liquids with amino acids as cations: Novel chiral ligands in chiral ligand-exchange capillary electrophoresis 期刊论文 Mu, Xiaoyu|Qi, Li|Zhang, Haizhi|Shen, Ying|Qiao, Juan|Ma, Huimin|
21 An Electrochemical Method for Investigation of Conformational Flexibility of Active Sites of Trametes versicolor Laccase Based on Sensitive Determination of Copper Ion with Cysteine-Modified Electrodes 期刊论文 Li, Xianchan|Yu, Ping|Yang, Lifen|Wang, Fuyi|Mao, Lanqun|
22 A new resorufin-based spectroscopic probe for simple and sensitive detection of benzoyl peroxide via deboronation 期刊论文 Chen, Wei|Li, Zhao|Shi, Wen|Ma, Huimin|
23 Determination of non-protein cysteine in human serum by a designed BODIPY-based fluorescent probe 期刊论文 Lu, Jinxin|Sun, Chengdong|Chen, Wei|Ma, Huimin|Shi, Wen|Li, Xiaohua|
24 Simple and fast fluorescence detection of benzoyl peroxide in wheat flour by N-methoxy rhodamine-6G spirolactam based on consecutive chemical reactions 期刊论文 Chen, Wei|Shi, Wen|Li, Zhao|Ma, Huimin|Liu, Yang|Zhang, Jinghua|Liu, Qingjun|
25 Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging 期刊论文 Qiao, Juan|Mu, Xiaoyu|Qi, Li|Deng, Jingjing|Mao, Lanqun|
26 Cysteine-modulated colorimetric sensing of extracellular Mg2+ in rat brain based on the strong chelation interaction between dithiothreitol and Mg2+ 期刊论文 Zhuang, Xuming|Wang, Dalei|Yang, Lifen|Yu, Ping|Jiang, Wei|Mao, Lanqun|
27 A graphene oxide-peptide fluorescence sensor for proteolytically active prostate-specific antigen 期刊论文 Feng, Tingting|Feng, Duan|Shi, Wen|Li, Xiaohua|Ma, Huimin|
28 Monolith and coating enzymatic microreactors of L-asparaginase: kinetics study by MCE-LIF for potential application in acute lymphoblastic leukemia (ALL) treatment 期刊论文 Qiao, Juan|Qi, Li|Mu, Xiaoyu|Chen, Yi|
29 In situ formation of three-dimensional and uniform Pt/Carbon nanotube nanocomposites from ionic liquid/carbon Nanotube gel matrix with enhanced electrocatalytic activity towards methanol oxidation 期刊论文 P. Yu, Q. Qian, Y. Q. Lin, L. Su, L. Q. Mao*|
30 Electrochemical impedance spectroscopic measurements of FCCP-induced change in membrane permeability of MDCK cells 期刊论文 Zhao, Lingzhi|Li, Xianchan|Lin, Yuqing|Yang, Lifen|Yu, Ping|Mao, Lanqun|
31 Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron 期刊论文 Mu, Xiaoyu|Qi, Li|Dong, Ping|Qiao, Juan|Hou, Jian|Nie, Zongxiu|Ma, Huimin|
32 Development of a new open-tubular capillary electrochromatography method for in vitro monitoring of toxic aromatic amines distribution in rat blood 期刊论文 Shen, Ying|Qi, Li|Qin, Jianglei|Zhang, Haizhi|Qiao, Juan|Chen, Yongming|Mao, Lanqun|
33 In vivo monitoring of hydrogen sulfide using a cresyl violet-based ratiometric fluorescence probe 期刊论文 Wan, Qiongqiong|Song, Yanchao|Li, Zhao|Gao, Xinghui|Ma, Huimin|
34 An unprecedented strategy for selective and sensitive fluorescence detection of nitric oxide based on its reaction with a selenide 期刊论文 C. Sun, W. Shi, Y. Song, W. Chen, H. Ma|
35 A highly specific ferrocene-based fluorescent probe for hypochlorous acid and its application to cell imaging 期刊论文 Chen, Suming|Lu, Jinxin|Sun, Chengdong|Ma, Huimin|
36 Immobilization of trypsin on sub-micron skeletal polymer monolith 期刊论文 Yao, Chunhe|Qi, Li|Hu, Wenbin|Wang, Fuyi|Yang, Gengliang|
37 Immobilization of trypsin via reactive polymer grafting from magnetic nanoparticles for microwave-assisted digestion 期刊论文 Shen, Ying|Guo, Wei|Qi, Li|Qiao, Juan|Wang, Fuyi|Mao, Lanqun|
38 A novel amphipathic block copolymer coating forming micelle-like aggregates for separation of steroids in open tubular capillary electrochromatography 期刊论文 Shen, Ying|Qi, Li|Qin, Jianglei|Yan, Huijuan|Qiao, Juan|Zhang, Haizhi|Chen, Yongming|Mao, Lanqun|Wan, Lijun|
39 Energy-efficient electrodeposition of metal-based nanostructures through simultaneous deposition at both the cathode and the anode 期刊论文 Ren, Lin|Yan, Jie|Yu, Ping|Mao, Lanqun|
40 Study on alanine aminotransferase kinetics by microchip electrophoresis 期刊论文 Mu, Xiaoyu|Qi, Li|Qiao, Juan|Zhang, Haizhi|Ma, Huimin|
41 Strong Interaction between Imidazolium-Based Polycationic Polymer and Ferricyanide: Toward Redox Potential Regulation for Selective In Vivo Electrochemical Measurements 期刊论文 Zhuang, Xuming|Wang, Dalei|Lin, Yuqing|Yang, Lifen|Yu, Ping|Jiang, Wei|Mao, Lanqun|
42 Electrocatalytic four-electron reduction of oxygen with copper (II)-based metal-organic frameworks 期刊论文 Mao, Junjie|Yang, Lifen|Yu, Ping|Wei, Xianwen|Mao, Lanqun|
43 Hybridization of Bioelectrochemically Functional Infinite Coordination Polymer Nanoparticles with Carbon Nanotubes for Highly Sensitive and Selective In Vivo Electrochemical Monitoring 期刊论文 Lu, Xulin|Cheng, Hanjun|Huang, Pengcheng|Yang, Lifen|Yu, Ping|Mao, Lanqun|
44 Bioelectrochemically Active Infinite Coordination Polymer Nanoparticles: One-Pot Synthesis and Biosensing Property 期刊论文 Huang, Pengcheng|Mao, Junjie|Yang, Lifen|Yu, Ping|Mao, Lanqun|
45 Design strategies for water-soluble small molecular chromogenic and fluorogenic probes 期刊论文 Li, Xiaohua|Gao, Xinghui|Shi, Wen|Ma, Huimin|
46 Real-time colorimetric assay of inorganic pyrophosphatase activity based on reversibly competitive coordination of Cu2+ between cysteine and pyrophosphate ion 期刊论文 J. J. Deng, Q. Jiang, Y. X. Wang, L. F. Yang, P.|
47 A Tunable Ratiometric pH Sensor Based on Carbon Nanodots for the Quantitative Measurement of the Intracellular pH of Whole Cells 期刊论文 Shi, Wen|Li, Xiaohua|Ma huimin|
48 Reactive polymer as a versatile toolbox for construction of multifunctional superparamagnetic nanocomposites 期刊论文 Shen, Ying|Zhao, Lingzhi|Qi, Li|Qiao, Juan|Mao, Lanqun|Chen, Yi|
49 Parallel comparative studies on the toxic effects of unmodified CdTe quantum dots, gold nanoparticles, and carbon nanodots on live cells as well as green gram sprouts 期刊论文 Y. C. Song, D. Feng, W. Shi, X. H. Li, H. M. Ma.*|
50 Biofuel cell-based self-powered biogenerators for online continuous monitoring of neurochemicals in rat brain 期刊论文 Cheng, Hanjun|Yu, Ping|Lu, Xulin|Lin, Yuqing|Ohsaka, Takeo|Mao, Lanqun|
51 Imaging Different Interactions of Mercury and Silver with Live Cells by a Designed Fluorescence Probe Rhodamine B Selenolactone 期刊论文 Shi, Wen|Sun, Shuna|Li, Xiaohua|Ma, Huimin|
52 Electrochemical Post-Treatment of Infinite Coordination Polymers: An Effective Route to Preparation of Pd Nanoparticles Supported onto Carbon Nanotubes with Enhanced Electrocatalytic Activity toward Ethanol Oxidation 期刊论文 Ren, Lin|Yang, Lifen|Yu, Ping|Wang, Yuexiang|Mao, Lanqun|
53 Colorimetric Detection of Glucose in Rat Brain Using Gold Nanoparticles 期刊论文 Jiang, Ying|Zhao, Hong|Lin, Yuqing|Zhu, Ningning|Ma, Yurong|Mao, Lanqun|
54 Application of rhodamine B thiolactone to fluorescence imaging of Hg2+ in Arabidopsis thaliana 期刊论文 Zhang, Yangyang|Shi, Wen|Feng, Duan|Ma, Huimin|Liang, Yan|Zuo, Jianru|
55 Alkaline Post-Treatment of Cd(II)-Glutathione Coordination Polymers: Toward Green Synthesis of Water-Soluble and Cytocompatible CdS Quantum Dots with Tunable Optical Properties 期刊论文 Huang, Pengcheng|Jiang, Qin|Yu, Ping|Yang, Lifen|Mao, Lanqun|
56 Ionic Liquid-Assisted Preparation of Laccase-Based Biocathodes with Improved Biocompatibility 期刊论文 Qian, Qin|Su, Lei|Yu, Ping|Cheng, Hanjun|Lin, Yuqing|Jin, Xiaoyong|Mao, Lanqun|
57 A long-wavelength fluorescent probe for imaging reduced glutathione in live cells 期刊论文 Lu, Jinxin|Song, Yanchao|Shi, Wen|Li, Xiaohua|Ma, Huimin|
58 Thermal responsive fluorescent block copolymer for intracellular temperature sensing 期刊论文 Qiao, Juan|Qi, Li|Shen, Ying|Zhao, Lingzhi|Qi, Cui|Shangguan, Dihua|Mao, Lanqun|Chen, Yi|
59 Competitive Coordination of Cu2+ between Cysteine and Pyrophosphate Ion: Toward Sensitive and Selective Sensing of Pyrophosphate Ion in Synovial Fluid of Arthritis Patients 期刊论文 Deng, Jingjing|Yu, Ping|Yang, Lifen|Mao, Lanqun|
60 Sensitive detection of ozone by a practical resorufin-based spectroscopic probe with extremely low background signal 期刊论文 Zhang, Yangyang|Shi, Wen|Li, Xiaohua|Ma, Huimin|
61 Spectroscopic probes with changeable pi-conjugated systems 期刊论文 Shi, Wen|Ma, Huimin|
62 ZeoliticImidazolate framework-based electrochemical biosensor for in vivo electrochemical measurements 期刊论文 W. J. Ma, Q. Jiang, P. Yu, L. F. Yang,* L. Mao.*|
63 Amphiphilic block copolymer modified magnetic nanoparticles for microwave-assisted extraction of polycyclic aromatic hydrocarbons in environmental water 期刊论文 Li, Nan|Qi, Li|Shen, Ying|Li, Yaping|Chen, Yi|
64 Microchip CE-LIF method for the hydrolysis of L-glutamine by using L-asparaginase enzyme reactor based on gold nanoparticle 期刊论文 Qiao, Juan|Qi, Li|Yan, Huijuan|Li, Yaping|Mu, Xiaoyu|
65 A near-infrared fluorescent probe for monitoring tyrosinase activity 期刊论文 Li, Xiaohua|Shi, Wen|Chen, Suming|Jia, Jia|Ma, Huimin|Wolfbeis, Otto S.|
66 7-((5-Nitrothiophen-2-yl)methoxy)-3H-phenoxazin-3-one as a spectroscopic off-on probe for highly sensitive and selective detection of nitroreductase 期刊论文 Li, Zhao|Gao, Xinghui|Shi, Wen|Li, Xiaohua|Ma, Huimin|
67 Anion-Exchange-Based Amperometric Assay for Heparin Using Polyimidazolium as Synthetic Receptor 期刊论文 Qi, Hetong|Zhang, Li|Yang, Lifen|Yu, Ping|Mao, Lanqun|
68 A non-oxidative electrochemical approach to online measurements of dopamine release through laccase-catalyzed oxidation and intramolecular cyclization of dopamine 期刊论文 Lin, Yuqing|Zhang, Zipin|Zhao, Lingzhi|Wang, Xiang|Yu, Ping|Su, Lei|Mao, Lanqun|
69 Electricity generation from carboxymethyl cellulose biomass: A new application of enzymatic biofuel cells 期刊论文 Cheng, Hanjun|Qian, Qin|Wang, Xiang|Yu, Ping|Mao, Lanqun|
70 Nitroreductase Detection and Hypoxic Tumor Cell Imaging by a Designed Sensitive and Selective Fluorescent Probe, 7-[(5-Nitrofuran-2-yl)methoxy]-3H-phenoxazin-3-one 期刊论文 Li, Zhao|Li, Xiaohua|Gao, Xinghui|Zhang, Yangyang|Shi, Wen|Ma, Huimin|
71 Study on the decrease of renal D-amino acid oxidase activity in the rat after renal ischemia by chiral ligand exchange capillary electrophoresis 期刊论文 Zhang, Haizhi|Qi, Li|Lin, Yuqing|Mao, Lanqun|Chen, Yi|
72 Spectroscopic Response of Ferrocene Derivatives Bearing a BODIPY Moiety to Water: A New Dissociation Reaction 期刊论文 Suming Chen, Wei Chen, Wen Shi, Huimin Ma|
73 Magnetically separable Fe3O4-Ag3PO4 sub-micrometre composite: facile synthesis, high visible light-driven photocatalytic efficiency, and good recyclability 期刊论文 Li, Gaiping|Mao, Lanqun|
74 Charge-transfer interaction between melamine and quinones: Towards voltammetric determination of melamine 期刊论文 Zhang, Limin|Li, Ting|Yu, Ping|Ohsaka, Takeo|Mao, Lanqun|
75 Online Electrochemical Monitoring of Dynamic Change of Hippocampal Ascorbate: Toward a Platform for In Vivo Evaluation of Antioxidant Neuroprotective Efficiency against Cerebral Ischemia Injury 期刊论文 Liu, Kun|Yu, Ping|Lin, Yuqing|Wang, Yuexiang|Ohsaka, Takeo|Mao, Lanqun|
76 A simple and sensitive method for visual detection of phosgene based on the aggregation of gold nanoparticles 期刊论文 Feng, Duan|Zhang, Yangyang|Shi, Wen|Li, Xiaohua|Ma, Huimin|
77 Rational Design and One-Step Formation of Multifunctional Gel Transducer for Simple Fabrication of Integrated Electrochemical Biosensors 期刊论文 Yu, Ping|Zhou, Heng|Cheng, Hanjun|Qian, Qin|Mao, Lanqun|
78 A novel chiral ligand exchange capillary electrophoresis system with amino acid ionic liquid as ligand and its application in screening D-amino-acid oxidase inhibitors 期刊论文 Mu, Xiaoyu|Qi, Li|Shen, Ying|Zhang, Haizhi|Qiao, Juan|Ma, Huimin|
79 Rhodamine B Piperazinoacetohydrazine: A Water-Soluble Spectroscopic Reagent for Pyruvic Acid Labeling 期刊论文 Jia, Jia|Wang, Ke|Shi, Wen|Chen, Suming|Li, Xiaohua|Ma, Huimin|
80 Fluorescence sensing of adenosine deaminase based on adenosine induced self-assembly of aptamer structures 期刊论文 Feng, Tingting|Ma, Huimin|
81 Graphene as a Spacer to Layer-by-Layer Assemble Electrochemically Functionalized Nanostructures for Molecular Bioelectronic Devices 期刊论文 Wang, Xiang|Wang, Jingfang|Cheng, Hanjun|Yu, Ping|Ye, Jianshan|Mao, Lanqun|
82 Rational Design of Surface/Interface Chemistry for Quantitative in Vivo Monitoring of Brain Chemistry 期刊论文 Zhang, Meining|Yu, Ping|Mao, Lanqun|
83 Online Electrochemical Measurements of Ca2+ and Mg2+ in Rat Brain Based on Divalent Cation Enhancement toward Electrocatalytic NADH Oxidation 期刊论文 Zhang, Zipin|Zhao, Lingzhi|Lin, Yuqing|Yu, Ping|Mao, Lanqun|
84 Potential-controllable green synthesis and deposition of metal nanoparticles with electrochemical method 期刊论文 Yu, Ping|Qian, Qin|Wang, Xiang|Cheng, Hanjun|Ohsaka, Takeo|Mao, Lanqun|
85 Preparation of poly(N-isopropylacrylamide)-grafted well-controlled 3D skeletal monolith based on E-51 epoxy resin for protein separation 期刊论文 Xin, Peiyong|Shen, Ying|Qi, Li|Yang, Gengliang|Chen, Yi|
86 A chiral ligand exchange CE essay with zinc(II)-L-valine complex for determining enzyme kinetic constant of L-amino acid oxidase 期刊论文 Qi, Li|Yang, Gengliang|Zhang, Haizhi|Qiao, Juan|
87 基于表界面化学的活体分析新原理和新方法的研究 奖励 毛兰群|于萍|张美宁|严乙铭|刘坤|苏磊|杨丽芬|
88 In vivo electrochemical monitoring of the change of cochlear perilymph ascorbate during salicylate-induced tinnitus 期刊论文 Liu, Junxiu|Yu, Ping|Lin, Yuqing|Zhou, Na|Li, Tao|Ma, Furong|Mao, Lanqun|
89 Microfluidic chip-based online electrochemical detecting system for continuous and simultaneous monitoring of ascorbate and Mg2+ in rat brain 期刊论文 X. Gao, P. Yu, Y. Wang, T. Ohsaka, J. Ye, L. Mao|
90 A graphene oxide-peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2 期刊论文 Feng, Duan|Zhang, Yangyang|Feng, Tingting|Shi, Wen|Li, Xiaohua|Ma, Huimin|
91 In vivo electrochemical monitoring of the change of cochlear perilymph ascorbate during salicylate-induced tinnitus 期刊论文 Liu, Junxiu|Yu, Ping|Lin, Yuqing|Zhou, Na|Li, Tao|Ma, Furong|Mao, Lanqun|
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