免疫性血小板减少症中DNA去甲基化在LKB1调控髓系抑制细胞中的作用及机制研究

81900121
2019
H0804.巨核细胞、血小板与相关疾病
侯宇
青年科学基金项目
研究员
山东大学
22万元
髓系抑制细胞;免疫调控;免疫性血小板减少症
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Significance of anti-HBc serological status in primary immune thrombocytopenia. 期刊论文 Wang L;Li L;Li C;Hou Y;Xu M;Yu Y;Ni X;Wang R;Wang H;Wang L;Peng J;Hou M
2 Platelet autoantibody specificity and response to rhTPO treatment in patients with primary immune thrombocytopenia 期刊论文 Yu Y;Hou Y;Zhao Y;Zhou H;Jing F;Liu Y;Peng J;Liu X;Hou M
3 Glucocorticoid receptor modulates myeloid-derived suppressor cell function via mitochondrial metabolism in immune thrombocytopenia 期刊论文 Hou Y;Xie J;Wang S;Li D;Wang L;Wang H;Ni X;Leng S;Li G;Hou M;Peng J
4 Low-dose decitabine modulates myeloid-derived suppressor cell fitness via LKB1 in immune thrombocytopenia 期刊论文 Xiaofei Ni;Lingjun Wang;Haoyi Wang;Tianshu Yu;Jie Xie;Guosheng Li;Yanfeng Liu;Hai Zhou;Miao Xu;Ming Hou;Jun Peng;Yu Hou
5 Atorvastatin restores imbalance of cluster of differentiation 4 (CD4)+ T cells in immune thrombocytopenia in vivo and in vitro 期刊论文 Xu P;Zhao Y;Yu T;Yu Y;Ni X;Wang H;Sun L;Han P;Wang L;Sun T;Liu X;Zhou H;Peng J;Hou M;Hou Y;Xu M
6 Tumor Necrosis Factor-α Blockade Corrects Monocyte/Macrophage Imbalance in Primary Immune Thrombocytopenia 期刊论文 Zhao Y;Xu P;Guo L;Wang H;Min Y;Feng Q;Hou Y;Sun T;Li G;Ji X;Qiu J;Peng J;Liu X;Hou M
7 Low-Dose Decitabine Inhibits Cytotoxic T Lymphocytes-Mediated Platelet Destruction via Modulating PD-1 Methylation in Immune Thrombocytopenia 期刊论文 Panpan Han;Tianshu Yu;Yu Hou;Yajing Zhao;Yang Liu;Yunqi Sun;Haoyi Wang;Pengcheng Xu;Guosheng Li;Tao Sun;Xiang Hu;Xinguang Liu;Lizhen Li;Jun Peng;Hai Zhou;Ming Hou
8 Identification of a pathogenic TUBB1 variant in a Chinese family with congenital macrothrombocytopenia through whole genome sequencing 期刊论文 Hou Y;Shao L;Zhou H;Liu Y;Fisk DG;Spiteri E;Zehnder JL;Peng J;Zhang BM;Hou M
9 Low-dose decitabine modulates T-cell homeostasis and restores immune tolerance in immune thrombocytopenia 期刊论文 Han P;Hou Y;Zhao Y;Liu Y;Yu T;Sun Y;Wang H;Xu P;Li G;Sun T;Hu X;Liu X;Li L;Peng J;Zhou H;Hou M
10 How we treat primary immune thrombocytopenia in adults 期刊论文 Liu XG;Hou Y;Hou M
11 Single-dose versus low-dose rituximab in corticosteroid-resistant or relapsed ITP: A multicenter, randomized, controlled study 期刊论文 Ni X;Li D;Yuan C;Yu Y;Wang H;Wang L;Yu T;Qin P;Peng J;Hou M;Shi Y;Hou Y
12 Inhibition of LDHA to Induce EEF2 Release Enhances Thrombocytopoiesis 期刊论文 Qidi Chen;Min Xin;Lingjun Wang;Lin Li;Yingzhi Shen;Yan Geng;Haojie Jiang;Yang Wang;Lin Zhang;Yanyan Xu;Yu Hou;Junling Liu;Xuemei Fan
13 High-dose dexamethasone plus recombinant human thrombopoietin vs high-dose dexamethasone alone as frontline treatment for newly diagnosed adult primary immune thrombocytopenia: A prospective, multicenter, randomized trial 期刊论文 Yu Y;Wang M;Hou Y;Qin P;Zeng Q;Yu W;Guo X;Wang J;Wang X;Liu G;Chu X;Yang L;Feng Y;Zhou F;Sun Z;Zhang M;Wang X;Wang Z;Ran X;Zhao H;Wang L;Zhang H;Bi K;Li D;Yuan C;Xu R;Wang Y;Zhou Y;Peng J;Liu XG;Hou M
14 Dexamethasone plus oseltamivir versus dexamethasone in treatment-naive primary immune thrombocytopenia: a multicentre, randomised, open-label, phase 2 trial 期刊论文 Lu Sun;Juan Wang;Linlin Shao;Chenglu Yuan;Hongguo Zhao;Daqi Li;Zhencheng Wang;Panpan Han;Yafei Yu;Miao Xu;Hongyu Zhao;Jihua Qiu;Hai Zhou;Xinguang Liu;Yu Hou;Jun Peng;Ming Hou
15 Enhancing regulatory T-cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia 期刊论文 Wang H;Yu T;An N;Sun Y;Xu P;Han P;Zhao Y;Wang L;Ni X;Li Y;Li G;Liu Y;Peng J;Hou M;Hou Y
16 A prospective, multicenter study of low dose decitabine in adult patients with refractory immune thrombocytopenia 期刊论文 Zhou H;Qin P;Liu Q;Yuan C;Hao Y;Zhang H;Wang Z;Ran X;Chu X;Yu W;Wang X;Hou Y;Peng J;Hou M
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