单分子荧光成像研究绿脓杆菌信号分子调控宿主细胞信号转导的分子机制

21735006
2017
B0404.化学与生物传感
方晓红
重点项目
研究员
中国科学院化学研究所
280万元
超分辨光学成像;原子力显微镜;单分子示踪;单分子荧光成像
2018-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Automated Stoichiometry Analysis of Single-Molecule Fluorescence Imaging Traces via Deep Learning 期刊论文 Jiachao Xu;Gege Qin;Fang Luo;Lina Wang;Rong Zhao;Nan Li;Jinghe Yuan;Xiaohong Fang
2 Ultrastable Fluorescent Polymer Dots for Stimulated Emission Depletion Bioimaging 期刊论文 Yayun Wu;Hefei Ruan;Rong Zhao;Zaizai Dong;Wenhui Li;Xiaojun Tang;Jinghe Yuan;Xiaohong Fang
3 Deep learning in single-molecule imaging and analysis: recent addvance and prospects 期刊论文 Xiaolong Liu;Yifei Jiang;Yutong Cui;Jinghe Yuan;Xiaohong Fang
4 Single-Molecule Imaging of Protein Interactions and Dynamics 期刊论文 Fang Luo;Gege Qin;Tie Xia;Xiaohong Fang
5 Aptamer-based fluorescence polarization assay for separation-free exosome quantification 期刊论文 Zhen Zhang;Chuanhao Tang;Libo Zhao;Li Xu;Wei Zhou;Zaizai Dong;Yuqing Yang;Qiqi Xie;Xiaohong Fang
6 A new small cell lung cancer biomarker identified by Cell-SELEX generated aptamers 期刊论文 Wei Zhou;Libo Zhao;Hongyu Yuan;Li Xu;Weihong Tan;Yongmei Song;Xiaohong Fang
7 Analyzing protein dynamics from fluorescence intensity traces using unsupervised deep learning network 期刊论文 Yuan Jinghe;Zhao Rong;Xu Jiachao;Cheng Ming;Qin Zidi;Kou Xiaolong;Fang Xiaohong
8 Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells 期刊论文 Li Wenhui;Xu Jiachao;Kou Xiaolong;Zhao Rong;Zhou Wei;Fang Xiaohong
9 Fluorescent Polymer Dot-Based Multicolor Stimulated Emission Depletion Nanoscopy with a Single Laser Beam Pair for Cellular Tracking 期刊论文 Yayun Wu;Hefei Ruan;Zaizai Dong;Rong Zhao;Yu Jianqiang;Xiaojun Tang;Xiaolong Kou;Xing Zhang;Manchen Wu;Fang Luo;Jinghe Yuan;Xiaohong Fang
10 细胞膜上信号转导蛋白的单分子成像与分析 期刊论文 梁钰昕;赵容;梁馨月;方晓红
11 A Microwell-Assisted Multiaptamer Immunomagnetic Platform for Capture and Genetic Analysis of Circulating Tumor Cells 期刊论文 Zaizai Dong;Chuanhao Tang;Libo Zhao;Jiachao Xu;Yayun Wu;Xiaojun Tang;Wei Zhou;Rong Zhao;Li Xu;Zhen Zhang;Xiaohong Fang
12 High-resolution imaging of graphene by tip-enhanced coherent anti-Stokes Raman scattering 期刊论文 Xiaolong Kou;Qian Zhou;Dong Wang;Jinghe Yuan;Xiaohong Fang;Lijun Wan
13 受激辐射损耗光学显微镜及其照明系统 专利 袁景和;于建强;方晓红
14 Surface-Engineered Gold Nanoclusters for Stimulated Emission Depletion and Correlated Light and Electron Microscopy Imaging 期刊论文 Hongwei Yang;Yayun Wu;Hefei Ruan;Feng Guo;Yuxin Liang;Gege Qin;Xiaolong Liu;Zhen Zhang;Jinghe Yuan;Xiaohong Fang
15 Fusion of clathrin and caveolae endocytic vesicles revealed by line-switching dual-color STED microscopy 期刊论文 Ruan Hefei;Yu Jianqiang;Wu Yayun;Tang Xiaojun;Yuan Jinghe;Fang Xiaohong
16 Quantitative Characterization of the Membrane Dynamics of Newly Delivered TGF-beta Receptors by Single-Molecule Imaging 期刊论文 Mingliang Zhang;Zhen Zhang;Kangmin He;Jimin Wu;Nan Li;Rong Zhao;Jinghe Yuan;Han Xiao;Youyi Zhang;Xiaohong Fang
17 Proteasome independent protein knockdown by smallmolecule inhibitor for the undruggable lung adenocarcinoma 期刊论文 Wei Zhou;Guogui Sun;Zhen Zhang;Libo Zhao;Li Xu;Hongyu Yuan;Shumu Li;Zaizai Dong;Yongmei Song;Xiaohong Fang
18 N-(3-Oxododecanoyl) Homoserine Lactone Is a Generalizable Plasma Membrane Lipid-Ordered Domain Modifier 期刊论文 Hefei Ruan;Chunlin Zou;Yanni Xu;Xiaohong Fang;Tie Xia;Yan Shi
19 受激辐射耗尽光学显微镜及其照明系统 专利 袁景和;于建强;方晓红
20 多色受激辐射耗尽超分辨成像装置、方法及光学显微镜 专利 阮贺飞;袁景和;于建强;方晓红
21 Effect of water-soluble fullerenes on macrophage surface ultrastrue revealed by scanning ion conductance microscopy 期刊论文 Hefei Ruan;Xuejie Zhang;Jinghe Yuan;Xiaohong Fang
22 Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution 期刊论文 Dingka Song;Junchen Meng;Jie Cheng;Zheng Fan;Pengyu Chen;Hefei Ruan;Zhongyuan Tu
23 Photorelease of Pyridines Using a Metal-Free Photoremovable Protecting Group 期刊论文 Xiaojun Tang;Yayun Wu;Rong Zhao;Xiaolong Kou;Zaizai Dong;Wei Zhou;Zhen Zhang;Weihong Tan;Xiaohong Fang
24 Simultaneous Detection of Exosomal Membrane Protein and RNA by Highly Sensitive Aptamer Assisted Multiplex−PCR 期刊论文 Zaizai Dong;Chuanhao Tang;Zhen Zhang;Wei Zhou;Rong Zhao;Lina Wang;Jiachao Xu;Yayun Wu;Jiang Wu;Xing Zhang;Li Xu;Libo Zhao;Xiaohong Fang
25 Analysis of the Diffusivity Change from Single-Molecule Trajectories on Living Cells 期刊论文 Rong Zhao;Jinghe Yuan;Nan Li;Yahong Sun;Tie Xia;Xiaohong Fang
26 G-Quadruplex-Induced Liquid-Liquid Phase Separation in Biomimetic Protocells 期刊论文 Liu Xuejiao;Xiong Yansong;Zhang Chunjuan;Lai Rongji;Liu Hui;Peng Ruizi;Fu Ting;Liu Qiaoling;Fang Xiaohong;Mann Stephen;Tan Weihong
27 受激辐射耗尽超分辨显微成像的研究进展及应用 期刊论文 Hefei Ruan;Yayun Wu;Jinghe Yuan;Yan Shi;Xiaohong Fang
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