PINK1在外源性胁迫条件致感音神经性聋中的作用机制研究

81771008
2017
H1404.听觉异常与平衡障碍
李建峰
面上项目
主任医师
山东大学
56万元
神经毒性;内质网应激;毛细胞保护;发病机制;药物性聋
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Activation of NLRX1-mediated autophagy accelerates the ototoxic potential of cisplatin in auditory cells 期刊论文 Yin Haiyan;Yang Qianqian;Cao Zhixin;Li Hongrui;Yu Zhaoyan;Zhang Guodong;Sun Gaoying;Man Rongjun;Wang Haibo;Li Jianfeng
2 PINKl特性及其作用的研究进展 期刊论文 李阳;李洪蕊;杨倩倩
3 Hydroxytyrosol enhances cisplatin-induced ototoxicity: Possible relation to the alteration in the activity of JNK and AIF pathways 期刊论文 Zhang Weiwei;Man Rongjun;Yu Xiaoyu;Yang Huiming;Yang Qianqian;Li Jianfeng
4 Paeoniflorin protects spiral ganglion neurons from cisplatin-induced ototoxicity: Possible relation to PINK1/BAD pathway 期刊论文 Yu X;Man R;Li Y;Yang Q;Li H;Yang H;Bai X;Yin H;Li J;Wang H
5 STK33 alleviates gentamicin-induced ototoxicity in cochlear hair cells and House Ear Institute-Organ of Corti 1 cells 期刊论文 Zhou Meijuan;Sun Gaoying;Zhang Lili;Zhang Guodong;Yang Qianqian;Yin Haiyan;Li Hongrui;Liu Wenwen;Bai Xiaohui;Li Jianfeng;Wang Haibo
6 PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway. 期刊论文 Yang Q;Sun G;Yin H;Li H;Cao Z;Wang J;Zhou M;Wang H;Li J
7 A Newly-Synthesized Chalcone Derivative of Ligustrazine Induces Caspase-Dependent and Apoptosis-Inducing Factor-Dependent Apoptosis in Cochlear Hair Cells 期刊论文 Man Rongjun;Yin Haiyan;Zhao Jia;Yang Qianqian;Yang Huiming;Yu Xiaoyu;Zhang Weiwei;Li Jianfeng
8 PINK1 Protects Against Gentamicin-Induced Sensory Hair Cell Damage: Possible Relation to Induction of Autophagy and Inhibition of p53 Signal Pathway 期刊论文 Yang Q;Zhou Y;Yin H;Li H;Zhou M;Sun G;Cao Z;Man R;Wang H;Li J
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