【30970643】黄精凝集素II诱导肿瘤细胞自噬和凋亡的分子机制研究国家自然基金项目

黄精凝集素II诱导肿瘤细胞自噬和凋亡的分子机制研究

项目批准号： 30970643

批准年份： 2009

学科分类： C0506.糖、脂生物化学

项目负责人：鲍锦库

资助类别：面上项目

负责人职称：教授

依托单位：四川大学

资助金额： 35万元

关键词：信号通路;蛋白相互作用;黄精凝集素II;凋亡和自噬;膜受体

起止时间： 2010-01-01到2012-12-31

中英文摘要
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序号	标题	类型	作者
1	Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure	期刊论文	Ding, Jingjin\|Bao, Jinku\|Zhu, Deyu\|Zhang, Ying\|Wang, Da-Cheng\|
2	Targeting apoptotic and autophagic pathways for cancer therapeutics	期刊论文	刘俊杰，鲍锦库\|
3	Polygonatum cyrtonema lectin, a potential antineoplastic drug targeting programmed cell death pathways	期刊论文	鲍锦库\|
4	Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death	期刊论文	鲍锦库\|
5	Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis via a caspase-dependent pathway as compared to Ophiopogon japonicus lectin	期刊论文	Zhang, Zi-ting\|Peng, Hao\|Li, Chun-yang\|Liu, Jun-jie\|Zhou, Ting-Ting\|Yan, Yi-fang\|Li, Yan\|Bao, Jin-ku\|
6	Molecular Modeling, Docking and Dynamic Simulation of GNA-related Lectins for Potential Prevention in Influenza Virus (H1N1)	期刊论文	徐怀龙\|鲍锦库\|
7	MicroRNA-modulated autophagic signaling networks in cancer	期刊论文	付雷蕾\|刘博\|鲍锦库\|
8	Microautophagy: lesser-known self-eating.	期刊论文	鲍锦库\|
9	A new chitin-binding lectin from rhizome of Setcreasea purpurea with antifungal, antiviral and apoptosis-inducing activities	期刊论文	Yao, Qing\|Wu, Chuan-fang\|Luo, Ping\|Xiang, Xiao-cong\|Liu, Jun-jie\|Mou, Lin\|Bao, Jin-ku\|
10	Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics	期刊论文	Li, Chun-yang\|Wang, En-qin\|Cheng, Yan\|Bao, Jin-ku\|
11	Agaricus bisporus lectins mediates islet b-cell proliferation	期刊论文	王轶\|鲍锦库\|
12	Antihyperglycemic Effect of Ginsenoside Rh2 by Inducing Islet β-cell Regeneration in Mice	期刊论文	鲍锦库\|
13	Plant lectins: Potential antineoplastic drugs from bench to clinic	期刊论文	Liu, Bo\|Bian, He-jiao\|Bao, Jin-ku\|
14	Purification, Characterization, and Molecular Cloning of a Novel Antifungal Lectin From the Roots of Ophioglossum pedunculosum	期刊论文	He, Xue-mei\|Ji, Na\|Xiang, Xiao-cong\|Luo, Ping\|Bao, Jin-ku\|
15	植物凝集素的功能	期刊论文	鲍锦库\|
16	The Global Component-Target Network in Panax Ginseng C	期刊论文	Zhang, Fan\|Li, Chun-Yang\|Wang, En-Qin\|Li, Wen-Wen\|Yu, Qi-Jia\|Wen, Xin\|Liu, Jun-Jie\|Bao, Jin-Ku\|
17	Concanavalin A: A potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics	期刊论文	Li, Wen-wen\|Yu, Jia-ying\|Xu, Huai-long\|Bao, Jin-ku\|
18	Network-Based Identification of Novel Connections Among Apoptotic Signaling Pathways in Cancer	期刊论文	王楠\|鲍锦库\|
19	Plant lectins: Targeting programmed cell death pathways as antitumor agents	期刊论文	Fu, Lei-lei\|Zhou, Cheng-cheng\|Yao, Shun\|Yu, Jia-ying\|Liu, Bo\|Bao, Jin-ku\|
20	Recombinant expression of Polygonatum cyrtonema lectin with anti-viral, apoptosis-inducing activities and preliminary crystallization	期刊论文	Li, Chun-yang\|Luo, Ping\|Liu, Jun-jie\|Wang, En-qin\|Li, Wen-wen\|Ding, Zhi-hao\|Mou, Lin\|Bao, Jin-ku\|
21	Network-based identification of novel connections among apoptotic signaling pathways in cancer.	期刊论文	鲍锦库\|
22	Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis	期刊论文	欧阳亮\|鲍锦库\|
23	In silico Analysis of Molecular Mechanisms of Galanthus nivalis Agglutinin-Related Lectin-Induced Cancer Cell Death from Carbohydrate-Binding Motif Evolution Hypothesis	期刊论文	Yu, Qi-jia\|Li, Zi-yue\|Yao, Shun\|Ming, Miao\|Wang, Shu-ya\|Liu, Bo\|Bao, Jin-ku\|
24	MicroRNA Regulation of Programmed Cell Death Pathways in Cancer	期刊论文	明苗\|赵旭\|鲍锦库\|
25	Characterization, molecular cloning, and in silico analysis of a novel mannose-binding lectin from Polygonatum odoratum (Mill.) with anti-HSV-II and apoptosis-inducing activities	期刊论文	Yang, Yun\|Xu, Huai-long\|Zhang, Zi-ting\|Liu, Jun-jie\|Li, Wen-wen\|Ming, Hua\|Bao, Jin-ku\|
26	Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras-Raf and PI3K-Akt signaling pathways	期刊论文	Liu, Bo\|Wu, Jin-ming\|Li, Jing\|Liu, Jun-jie\|Li, Wen-wen\|Li, Chun-yang\|Xu, Huai-long\|Bao, Jin-ku\|
27	Autophagic pathways as new targets for cancer drug development	期刊论文	Liu, Bo\|Cheng, Yan\|Liu, Qian\|Bao, Jin-ku\|Yang, Jin-Ming\|

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