CRISPR/Cas9介导的全基因组敲除鉴定急性淋巴细胞白血病蒽环类耐药的相关基因

81870135
2018
H0809.白血病
胡建达
面上项目
教授
福建医科大学
57万元
耐药;CRISPR/Cas9;急性淋巴细胞白血病;蒽环类;预后
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 In Vitro Investigation of the Cytotoxic Activity of Emodin 35 Derivative on Multiple Myeloma Cell Lines 期刊论文 Zheng J;Chen YY;Zheng ZH;Chen YX;Chai YJ;Wang WF;Asakawa T;Hu JD
2 RNA测序联合CRISPR/Cas9基因编辑技术鉴定调控维甲酸诱导分化功能的miRNA. 期刊论文 王凌燕;林仁章;江佩芳;张雲;李佳蒸;陈钰雯;胡建达
3 Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia 期刊论文 陈艳欣;江佩芳;温晶晶;吴正军;李佳蒸;陈钰雯;王凌燕;甘东辉;陈英玉;杨婷;林敏辉;胡建达
4 Clinical characteristics and prognosis of patients with co-existing follicular lymphoma and diffuse large B-cell lymphoma components in rituximab era 期刊论文 陈溢;罗璐婷;陈鹭珊;郑晓云;杨小珠;郑志宏;郑静;刘庭波;杨婷;胡建达
5 Loss of MiR-155 Sensitizes FLT3-ITD+AML to Chemotherapy and FLT3 Inhibitors via Glycolysis Blocking by Targeting PIK3R1 期刊论文 王凌燕;江佩芳;李佳蒸;黄燕;温晶晶;吴正军;陈艳欣;胡建达
6 Antifungal Strategy in Patients with Invasive Fungal Disease Associated with Hematological Malignancies Based on Risk Stratification 期刊论文 陈力津;罗璐婷;陈艳欣;王引舟;李静;郑晓云;杨婷;胡建达
7 Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma 期刊论文 李佳蒸;黄燕;张云;温晶晶;陈艳欣;王凌燕;江佩芳;胡建达
8 Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Activity in Acute Lymphoblastic Leukemia Cells in vitro and in vivo 期刊论文 甘东辉;陈钰雯;吴正军;罗丽萍;Yirga Shimuye Kalayu;张娜;叶福;陈海军;胡建达;陈英玉
9 Identification of Early Recurrence Factors in Childhood and Adolescent B-Cell Acute Lymphoblastic Leukemia Based on Integrated Bioinformatics Analysis 期刊论文 黄燕;李佳蒸;陈艳欣;江佩芳;王凌燕;胡建达
10 双sgRNA介导的miR-155基因敲除对FLT3-ITD~+AML细胞系的药物敏感性的影响. 期刊论文 王凌燕;江佩芳;李佳蒸;胡建达
11 Genomic heterogeneity contributed to different prognosis between adult and pediatric acute lymphoblastic. 期刊论文 陈艳欣;郑湧智;洪允达;温晶晶;李佳蒸;黄燕;陈溢;郑晓云;杨婷;徐杨棋;郑静;胡建达
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