FSH通过调控HMGCR对肝脏胆固醇合成的影响及分子机制
81670796
2016
H0710.脂质代谢异常
赵家军
面上项目
教授
山东大学
58万元
卵泡刺激素;脂代谢;胆固醇;胆固醇合成限速酶;肝脏
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol | 奖励 | 郭艳静;赵家军 |
| 2 | CRTC2通过FoxO1/SREBP-2/HMGCR调节肝脏胆固醇的合成的研究/TSH 通过上调肝脏中CRTC2的表达促进肝脏糖异生的研究 | 奖励 | 李玉杰;赵家军;高聆 |
| 3 | Expression of FSHR in chondrocytes and the effect of FSH on chondrocytes | 期刊论文 | Kong D;Guan Q;Li G;Xin W;Qi X;Guo Y;Zhao J;Xu J;Sun S;Gao L |
| 4 | FSHR ablation induces depression-like behaviors | 期刊论文 | Wen-kai Bi;Shan-shan Shao;Zhi-wei Li;Yong-wei Ruan;Si-si Luan;Zhen-hua Dong;Jing Wang;Shan-shan Wu;Tian Guo;Shi-zhan Ma;Ling Gao;Jia-jun Zhao;Zhao He |
| 5 | Follicle-stimulating hormone enhances hepatic gluconeogenesis by GRK2-mediated AMPK hyperphosphorylation at Ser485 in mice | 期刊论文 | Qi Xiaoyi;Guo Yanjing;Song Yongfeng;Yu Chunxiao;Zhao Lifang;Fang Li;Kong Dehuan;Zhao Jiajun;Gao Ling |
| 6 | 卵泡雌激素诱发肝脏胆固醇代谢絮乱机制研究 | 奖励 | 郭艳静;高聆;赵家军 |
| 7 | Role of exosome - associated micro RNA in diagnostic and therapeuticapplications to metabolic disorders. | 期刊论文 | Zhenyu YAO;Wenbin CHEN;Shanshan SHAO;Shizha MA;Chongbo YANG;Mengzhu LI;Jiajun ZHAO;Ling GAO |
| 8 | A Novel Role for CRTC2 in Hepatic Cholesterol Synthesis via SREBP-2 | 期刊论文 | Yujie Li;Yongfeng Song;Meng Zhao;Yanjing Guo;Chunxiao Yu;Wenbin Chen;Shanshan Shao;Chao Xu;Xinli Zhou;Lifang Zhao;Zhenhai Zhang;Tao Bo;Yu Xia;Christopher G. Proud;Xuemin Wang;Li Wang;Jiajun Zhao;Ling Gao |
| 9 | Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol | 期刊论文 | Guo Yanjing;Zhao Meng;Bo Tao;Ma Shizhan;Yuan Zhongshang;Chen Wenbin;He Zhao;Hou Xu;Liu Jun;Zhang Zhenhai;Zhu Qiang;Wang Qiangxiu;Lin Xiaoyan;Yang Zhongli;Cui Min;Liu Lu;Li Yujie;Yu Chunxiao;Qi Xiaoyi;Wang Qian;Zhang Haiqing;Guan Qingbo;Zhao Lifang;Xuan shimeng;Yan huili;Liu yanliang;Wang Li;Li Qihang;Song Yongfeng;Gao Ling;Zhao jiajun |
| 10 | Thyroid Stimulating Hormone Triggers Hepatic Mitochondrial Stress through Cyclophilin D Acetylation | 期刊论文 | Xiaolei Wang;Jinbao Mao;Xinli Zhou;Qiu Li;Ling Gao;Jiajun Zhao |
| 11 | FSH signaling is involved in affective disorders | 期刊论文 | Wen-kai Bi;Si-si Luan;Jing Wang;Shan-shan Wu;Xin-chen Jin;Yi-lin Fu;Ling Gao;Jia-jun Zhao;Zhao He |
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