CYLD调节脂自噬对肾癌转移及索拉菲尼耐药的影响及机制

81602227
2016
H1815.肿瘤靶向治疗
刘帅
青年科学基金项目
副主任医师
山东大学
17万元
脂代谢;圆柱瘤基因;脂自噬;转移;肾肿瘤
2017-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 山东省高等学校科学技术奖 奖励 吕家驹;丁森泰;孙亮;刘帅
2 Autophagy flux inhibition, G2/M cell cycle arrest and apoptosis induction by ubenimex in glioma cell lines. 期刊论文 Han Liping;Zhang Yongfei;Liu Shuai;Zhao Qingwei;Liang Xianhong;Ma Zhiguo;Gupta Prakash K;Zhao Miaoqing;Wang Aihua
3 Risk assessment models to evaluate the necessity of prostate biopsies in North Chinese patients with 4-50 ng/mL PSA. 期刊论文 Zhao Jing;Liu Shuai;Gao Dexuan;Ding Sentai;Niu Zhihong;Zhang Hui;Huang Zhilong;Qiu Juhui;Li Qing;Li Ning;Xie Fang;Cui Jilei;Lu Jiaju
4 Silencing Livin improved the sensitivity of colon cancer cells to 5-fluorouracil by regulating crosstalk between apoptosis and autophagy. 期刊论文 Liu Shuai;Li Xin;Li Qing;Liu Hongjun;Shi Yulong;Zhuo Hongqing;Li Chensheng;Zhu Huijuan
5 山东医学科技奖 奖励 牛志宏;刘帅;刘征;赵继明;王建伟;解放
6 Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. 期刊论文 Liu Shuai;Gao Mingwei;Wang Xiaoqing;Ding Sentai;Lv Jiaju;Gao Dexuan;Wang Zhiyang;Niu Zhihong
7 HADHA overexpression disrupts lipid metabolism and inhibits tumor growth in clear cell renal cell carcinoma 期刊论文 Liu Shuai;Liu Xiaoli;Wu Fei;Zhang Xufeng;Zhang Hui;Gao Dexuan;Bi Dongbin;Qu Hongyi;Ge Juntao;Xu Yue;Zhao Zuohui
8 山东省药学会科学技术奖 奖励 牛志宏;刘帅;刘征;赵继明;王建伟;解放
9 Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells. 期刊论文 Wang Zhiyang;Liu Shuai;Ding Kejia;Ding Sentai;Li Chensheng;Lu Jiaju;Gao Dexuan;Zhang Tong;Bi Dongbin
10 Ubenimex enhances Brd4 inhibition by suppressing HEXIM1 autophagic degradation and suppressing the Akt pathway in glioma cells. 期刊论文 Han Liping;Zhao Qingwei;Liang Xianhong;Wang Xiaoqing;Zhang Zhen;Ma Zhiguo;Zhao Miaoqing;Wang Aihua;Liu Shuai
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