LncRNA-PVT1通过Pygo2调控细胞自噬在胰腺癌吉西他滨耐药中的分子机制研究
31701228
2017
C0702.细胞信号转导
周策凡
青年科学基金项目
研究员
湖北工业大学
27万元
长链非编码RNA;乙酰化;甲基化;自噬;信号转导
2018-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/beta-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes | 期刊论文 | Zhou Cefan;Yi Changhua;Yi Yongxiang;Qin Wenying;Yan Yanan;Dong Xueying;Zhang Xuewen;Huang Yuan;Zhang Rui;Wei Jie;Ali Declan William;Michalak Marek;Chen Xing-Zhen;Tang Jingfeng |
| 2 | Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy. | 期刊论文 | Huang Yuan;Li Shi;Jia Zhenhua;Zhao Weiwei;Zhou Cefan;Zhang Rui;Ali Declan William;Michalak Marek;Chen Xing-Zhen;Tang Jingfeng |
| 3 | TRIM4 interacts with TRPM8 and regulates its channel function through K423-mediated ubiquitination. | 期刊论文 | Huang Yuan;Li Shunyao;Jia Zhenhua;Li Shi;He Wenzao;Zhou Cefan;Zhang Rui;Xu Rui;Sun Bo;Ali Declan William;Michalak Marek;Chen Xing-Zhen;Tang Jingfeng |
| 4 | Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction | 期刊论文 | Zhou Cefan;Wang Ming;Yang Jing;Xiong Hui;Wang Yefu;Tang Jingfeng |
| 5 | TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer | 期刊论文 | Zhou Cefan;Liang Yanyan;Zhou Li;Yan Yanan;Liu Nanxi;Zhang Rui;Huang Yuan;Wang Ming;Tang Yongfei;Ali Declan William;Wang Yefu;Michalak Marek;Chen Xing-Zhen;Tang Jingfeng |
| 6 | STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I | 期刊论文 | Zhou Cefan;Qian Xuehong;Hu Miao;Zhang Rui;Liu Nanxi;Huang Yuan;Yang Jing;Zhang Juan;Bai Hua;Yang Yuyan;Wang Yefu;Ali Declan;Michalak Marek;Chen Xing Zhen;Tang Jingfeng |
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