集成建模和数据挖掘方法的乳腺癌网络随机动力学研究

11771098
2017
A0604.生物与生命科学中的数学
李春贺
面上项目
副教授
复旦大学
48万元
随机动力学模型;生物大数据;细胞命运;基因调控网络模型;计算系统生物学
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Quantifying the interplay between genetic and epigenetic regulations in stem cell development 期刊论文 Yunbin Zhang;Ning Liu;Wei Lin;Chunhe Li
2 Landscape of gene networks for random parameter perturbation 期刊论文 Chunhe Li
3 A Dimension Reduction Approach for Energy Landscape: Identifying Intermediate States in Metabolism-EMT Network 期刊论文 Xin Kang;Chunhe Li
4 Landscape reveals critical network structures for sharpening gene expression boundaries 期刊论文 Chunhe Li;Lei Zhang;Qing Nie
5 Landscape inferred from gene expression data governs pluripotency in embryonic stem cells 期刊论文 Xin Kang;Chunhe Li
6 Landscape and flux govern cellular mode-hopping between oscillations 期刊论文 Chunhe Li;Leijun Ye
7 Quantifying the Landscape and Transition Paths for Proliferation–Quiescence Fate Decisions 期刊论文 Zihao Chen;Chunhe Li
8 Landscape and flux quantify the stochastic transition dynamics for p53 cell fate decision 期刊论文 Leijun Ye;Zhuoqing Song;Chunhe Li
9 Exposing the Underlying Relationship of Cancer Metastasis to Metabolism and Epithelial-Mesenchymal Transitions 期刊论文 Xin Kang;Jin Wang;Chunhe Li
10 A landscape view on the interplay between EMT and cancer metastasis 期刊论文 Chunhe Li;Gabor Balazsi
11 Uncovering the cell fate decision in lysis-lysogeny transition and stem cell development via Markov state modeling 期刊论文 Xiaoguang Li;Tongkai Li;Chunhe Li;Tiejun Li
12 Quantifying the landscape of decision making from spiking neural networks 期刊论文 Leijun Ye;Chunhe Li
13 An enriched network motif family regulates multistep cell fate transitions with restricted reversibility 期刊论文 Yujie Ye;Xin Kang;Jordan Bailey;Chunhe Li;Tian Hong
14 2020国际华人数学家大会最佳论文奖(2020 ICCM Best paper award) 奖励 Yujie Ye;Xin Kang;Jordan Bailey;Chunhe Li;Tian Hong
15 Revealing the mechanism of lymphoid and myeloid cell differentiation and transdifferentiation through landscape quantification 期刊论文 Chenyong Zhang;Chunhe Li
16 Landscape and kinetic path quantify critical transitions in epithelial-mesenchymal transition 期刊论文 Jintong Lang;Qing Nie;Chunhe Li
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