AMPK在糖尿病抑制腹主动脉瘤形成中的作用及转化医学研究
81470591
2014
H0211.血管发生及血管结构与功能异常
张淼
面上项目
教授
山东大学
73万元
AMP;腹主动脉瘤;糖尿病;活化的蛋白激酶;转化医学
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability. | 期刊论文 | Ye Ding;Miao Zhang;Wencheng Zhang;Qiulun Lu;Zhejun Cai;Ping Song;Imoh Sunday Okon;Lei Xiao;Ming-Hui Zou |
| 2 | S-Nitrosylation of Prostacyclin Synthase Instigates Nitrate Cross-Tolerance In Vivo. | 期刊论文 | Zhou Sheng-Nan;Lu Jun-Xiu;Wang Xue-Qing;Shan Mei-Rong;Miao Zhang;Pan Guo-Pin;Jian Xu;Li Peng;Ping Song;Pang Xin-Yan;Bai Yong-Ping;Liu Chao;Wang Shuang-Xi |
| 3 | Vitamin B6 prevents isocarbophos-induced vascular dementia in rats through N-methyl-D-aspartate receptor signaling. | 期刊论文 | Li Peng;Zhu Mo-Li;Pan Guo-Pin;Lu Jun-Xiu;Zhao Fan-Rong;Jian Xu;Liu Li-Ying;Wan Guang-Rui;Chen Yuan;Ping Song;Wang Shuang-Xi;Hu Chang-Ping |
| 4 | Administration of losartan improves aortic arterial stiffness and reduces the occurrence of acute coronary syndrome in aged patients with essential hypertension. | 期刊论文 | Zhang Zhi-Mian;Wang Bing-Xiang;Ou Wen-Sheng;Lv Yan-Hong;Li Ming-Min;Miao Zhang;Wang Shuang-Xi;Fei Jian-Chun;Guo Tao |
| 5 | Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation in Apoe (-/-) Mice Fed with High-Fat Diet. | 期刊论文 | Liu Zhan;Li Peng;Zhao Zhi-Hong;Zhang Yu;Ma Zhi-Min;Wang Shuang-Xi |
| 6 | Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo. | 期刊论文 | Yang Jing-Jing;Li Peng;Wang Fu;Liang Wen-Jing;Ma Hui;Chen Yuan;Ma Zhi-Min;Li Quan-Zhong;Peng Qi-Sheng;Zhang Yun;Wang Shuang-Xi |
| 7 | Chronic administration of isocarbophos induces vascular cognitive impairment in rats. | 期刊论文 | Li Peng;Yin Ya-Ling;Zhu Mo-Li;Pan Guo-Pin;Zhao Fan-Rong;Lu Jun-Xiu;Liu Zhan;Wang Shuang-Xi;Hu Chang-Ping |
| 8 | Lovastatin upregulates microRNA-29b to reduce oxidative stress in rats with multiple cardiovascular risk factors. | 期刊论文 | Wang Fu;Ma Hui;Liang Wen-Jing;Yang Jing-Jing;Wang Xue-Qing;Shan Mei-Rong;Chen Yuan;Jia Min;Yin Ya-Ling;Sun Xue-Ying;Zhang Jia-Ning;Peng Qi-Sheng;Chen Yu-Guo;Liu Li-Ying;Li Peng;Guo Tao;Wang Shuang-Xi |
| 9 | Traditional Chinese medicine xin-mai-jia recouples endothelial nitric oxide synthase to prevent atherosclerosis in vivo. | 期刊论文 | Yin Ya-Ling;Zhu Mo-Li;Wan Jia;Zhang Chong;Pan Guo-Pin;Lu Jun-Xiu;Ping Song;Chen Yuan;Zhao Fan-Rong;Yu Hai-Ya;Guo Tao;Jian Xu;Liu Li-Ying;Zhang Jia-Ning;Wan Guang-Rui;Wang Shuang-Xi;Li Peng |
| 10 | Inhibition of NA(+)/H(+) Exchanger 1 Attenuates Renal Dysfunction Induced by Advanced Glycation End Products in Rats. | 期刊论文 | Li Peng;Chen Geng-Rong;Wang Fu;Xu Ping;Liu Li-Ying;Yin Ya-Ling;Wang Shuang-Xi |
| 11 | Rosiglitazone via PPARgamma-dependent suppression of oxidative stress attenuates endothelial dysfunction in rats fed homocysteine thiolactone. | 期刊论文 | Yang Xu-Hong;Li Peng;Yin Ya-Ling;Tu Jiang-Hua;Dai Wen;Liu Li-Ying;Wang Shuang-Xi |
| 12 | Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms. | 期刊论文 | Ma Hui;Liang Wen-Jing;Shan Mei-Rong;Wang Xue-Qing;Zhou Sheng-Nan;Chen Yuan;Guo Tao;Li Peng;Yu Hai-Ya;Liu Chao;Yin Ya-Ling;Wang Yu-Lin;Dong Bo;Pang Xin-Yan;Wang Shuang-Xi |
| 13 | Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo. | 期刊论文 | Li Peng;Yin Ya-Ling;Guo Tao;Sun Xue-Ying;Ma Hui;Zhu Mo-Li;Zhao Fan-Rong;Xu Ping;Chen Yuan;Wan Guang-Rui;Jiang Fan;Peng Qi-Sheng;Liu Chao;Liu Li-Ying;Wang Shuang-Xi |
| 14 | Berberine suppresses the ectopic expression of miR-133a in endothelial cells to improve vascular dementia in diabetic rats. | 期刊论文 | Yin Sen;Bai Wenwu;Li Peng;Jian Xu;Shan Tichao;Tang Zhenyu;Jing Xuejiao;Ping Song;Li Quanzhong;Miao Zhang;Wang Shuangxi;Ou Wensheng;Fei Jianchun;Guo Tao |
| 15 | AMPKalpha inactivation destabilizes atherosclerotic plaque in streptozotocin-induced diabetic mice through AP-2alpha/miRNA-124 axis. | 期刊论文 | Liang Wen-Jing;Zhou Sheng-Nan;Shan Mei-Rong;Wang Xue-Qin;Zhang Miao;Chen Yuan;Zhang Yun;Wang Shuang-Xi;Guo Tao |
| 16 | Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. | 期刊论文 | Wang Jie;Guo Tao;Peng Qi-Sheng;Yue Shou-Wei;Wang Shuang-Xi |
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