抗表皮生长因子受体的金纳米人工抗体的结构机制与抗肿瘤性能研究

31871007
2018
C1007.纳米生物学
曹傲能
面上项目
教授
上海大学
59万元
纳米材料与蛋白相互作用;生物纳米材料;人工抗体;纳米蛋白质;纳米材料与细胞相互作用
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Click Nanogels from pH-Labile Dextran Prodrugs for Robust Solid Tumor Chemotherapy 期刊论文 Rong Jin;Minqiang Wang;Liefu Zhou;Zhengshi Yang;Qing Chang;Aoneng Cao
2 Dual-Responsive Click-Crosslinked Micelles Designed for Enhanced Chemotherapy for Solid Tumors 期刊论文 Rong Jin;Jing Sun;Liefu Zhou;Xuelian Guo;Aoneng Cao
3 In Vivo Fate of Ag2Te Quantum Dot and Comparison with other NIR-II Silver Chalcogenide Quantum Dots 期刊论文 Jun-Zheng Zhang;Huan Tang;Xing-Zhu Chen;Qianqian Su;Wen-Song Xi;Yuan-Yuan Liu;Yuanfang Liu;Aoneng Cao;Haifang Wang
4 Effects of VO2 Nanoparticles on Human Liver HepG2 Gells: Cytotoxicity, genotoxicity, and Glucose and Lipid Metabolism Disorders 期刊论文 Jia-Bei Li;Wen-Song Xi;Shi-Ying Tan;Yuan-Yuan Liu;Hao Wu;Yuanfang Liu;Aoneng Cao;Haifang Wang
5 Cytotoxicity and Genotoxicity of Low-Dose Vanadium Dioxide Nanoparticles to Lung Cells Following Long-Term Exposure 期刊论文 Wen-Song Xi;Jia-Bei Li;Yuan-Yuan Liu;Hao Wu;Aoneng Cao;Haifang Wang
6 石墨烯微结构调控及其表界面效应研究 奖励 吴明红;潘登余;曹傲能;涂育松;王海芳
7 具有氧化还原响应的聚合物交联胶束及其制备方法 专利 金荣;周列甫;郭雪连;曹傲能
8 一种人工表皮生长因子与设计多肽及其应用 专利 曹傲能;罗磊;刘元元;王海芳
9 一种基于金纳米粒子的人工抗体构建方法 专利 曹傲能;邵珠学;王海芳
10 Characterization of the Specific Interactions between Nanoparticles and Proteins at Residue-Resolution by Alanine Scanning Mutagenesis 期刊论文 Lei Luo;Yuan-Yuan Liu;Tiange Gao;Xinping Wang;Jingqi Chen;Haifang Wang;Yuanfang Liu;Aoneng Cao
11 蛋白质结构的“限域下最低能量结构片段”假说与蛋白质进化的 “石器时代” 期刊论文 曹傲能
12 Short-Term and Long-Term Toxicological Effects of Vanadium Dioxide Nanoparticles on A549 Cells 期刊论文 Wen-Song Xi;Zheng-Mei Song;Zhang Chen;Ni Chen;Gui-Hua Yan;Yanfeng Gao;Aoneng Cao;Yuanfang Liu;Haifang Wang
13 Unexpected Size Effect: The Interplay between Different-Sized Nanoparticles in Their Cellular Uptake 期刊论文 Ling Li;Wen-Song Xi;Qianqian Su;Yang Li;Gui-Hua Yan;Yuanfang Liu;Haifang Wang;Aoneng Cao
14 金抗体替代ELISA中的天然抗体用于溶菌酶检测 期刊论文 许艳娇;李文浩;高天歌;曹傲能
15 Folding of Flexible Protein Fragments and Design of Nanoparticle-Based Artificial Antibody Targeting Lysozyme 期刊论文 Yan Wang;Xinping Wang;Tiange Gao;Chenxi Lou;Haifang Wang;Yuanfang Liu;Aoneng Cao
16 多肽、抗溶菌酶人工抗体及其应用 专利 曹傲能;王新平;刘春园;王海芳
17 Cytotoxicity and RNA-SequencingAnalysis of Macrophages after Exposure to Vanadium Dioxide Nanoparticles 期刊论文 Wen-Song Xi;Jia-Bei Li;Xue-Rui Tang;Shi-Ying Tan;Aoneng Cao;Yuanfang Liu;Haifang Wang
18 A Potential MDM2 Inhibitor Formed by Restoring the Native Conformation of the p53 α‐Helical Peptide on Gold Nanoparticles 期刊论文 Qi Liu;Lingjie Sheng;Yuan-Yuan Liu;Tiange Gao;Haifang Wang;Yuanfang Liu;Aoneng Cao
19 The Last Secret of Protein Folding: The Real Relationship Between Long-Range Interactions and Local Structures 期刊论文 Aoneng Cao
20 Fate of CdSe/ZnS Quantum Dots in Cells: Endocytosis, Translocation and Exocytosis 期刊论文 Yuan-Yuan Liu;Qing Chang;Zao-Xia Sun;Jie Liu;Xiaoyong Deng;Yuanfang Liu;Aoneng Cao;Haifang Wang
21 一种多肽及其抗弹性蛋白酶的金纳米抗体 专利 曹傲能;喻凤;王新平;王海芳
22 基于金纳米粒子的靶向表皮生长因子受体EGFR的人工抗体及其制备方法 专利 曹傲能;汪坤;王海芳
23 Effects of carbon dots surface functionalities on cellular behaviors - Mechanistic exploration for opportunities in manipulating uptake and translocation 期刊论文 Gui-Hua Yan;Zheng-Mei Song;Yuan-Yuan Liu;Qianqian Su;Weixiong Liang;Aoneng Cao;Ya-Ping Sun;Haifang Wang
24 多肽及其制备方法、抗p53蛋白的人工抗体及其应用 专利 曹傲能;夏渝江;陈星竹;王海芳
25 一种多肽以及能靶向HIV包膜蛋白gp120的金纳米抗体 专利 曹傲能;倪睿;夏渝江;王海芳
26 Biotinylated Au Nanoparticle-Based Artificial Antibody for Detection of Lysozyme by the Lateral Flow Immunoassay and Enzyme-Linked Immunosorbent Assay 期刊论文 Wenhao Li;Tiange Gao;Chenxi Lou;Haifang Wang;Yuanfang Liu;Aoneng Cao
27 Conformationally Engineering Flexible Peptides on Silver Nanoparticles 期刊论文 Jia Xu;Tiange Gao;Lingjie Sheng;Yan Wang;Chenxi Lou;Haifang Wang;Yuanfang Liu;Aoneng Cao
28 PEGylation of Goldbody: PEG-aided Conformational Engineering of Peptides on Gold Nanoparticles 期刊论文 Tiange Gao;Yuan-Yuan Liu;Chenxi Lou;Haifang Wang;Yuanfang Liu;Aoneng Cao
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