牡蛎夏季病害发生及生态免疫防治机理研究

U1706204
2017
C1907.水产生物免疫学
宋林生
联合基金项目
教授
大连海洋大学
280万元
贝类病害;免疫防御;生态免疫学;微生物群落;温度胁迫
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Recent Advances of Shell Matrix Proteins and Cellular Orchestration in Marine Molluscan Shell Biomineralization 期刊论文 Song Xiaorui;Liu Zhaoqun;Wang Lingling;Song Linsheng
2 The neuroendocrine-immune regulation in response to environmental stress in marine bivalves. 期刊论文 Liu Zhaoqun;Li Meijia;Yi Qilin;Wang Lingling;Song Linsheng
3 A new member of the runt domain family from Pacific oyster Crassostrea gigas (CgRunx) potentially involved in immune response and larvae hematopoiesis 期刊论文 Song Xiaorui;Song Ying;Dong Miren;Liu Zhaoqun;Wang Weilin;Wang Lingling;Song Linsheng
4 Ocean acidification inhibits initial shell formation of oyster larvae by suppressing the biosynthesis of serotonin and dopamine 期刊论文 Liu Zhaoqun;Zhou Zhi;Zhang Yukun;Wang Lingling;Song Xiaorui;Wang Weilin;Zheng Yan;Zong Yanan;Lv Zhao;Song Linsheng
5 Transcriptional changes of Pacific oyster Crassostrea gigas reveal essential role of calcium signal pathway in response to CO2-driven acidification 期刊论文 Wang Xiudan;Wang Mengqiang;Wang Weilin;Liu Zhaoqun;Xu Jiachao;Jia Zhihao;Chen Hao;Qiu Limei;Lv Zhao;Wang Lingling;Song Linsheng
6 A serotonin receptor (Cg5-HTR-1) mediating immune response in oyster Crassostrea gigas 期刊论文 Jia Yunke;Yang Bin;Dong Wenjing;Liu Zhaoqun;Lv Zhao;Jia Zhihao;Qiu Limei;Wang Lingling;Song Linsheng
7 A novel JNK is involved in immune response by regulating IL expression in oyster Crassostrea gigas 期刊论文 Sun Jiejie;Li Yinan;Li Meijia;Liu Yu;Qu Chen;Wang Lingling;Song Linsheng
8 A novel tumor necrosis factor in the Pacific oyster Crassostrea gigas mediates the antibacterial response by triggering the synthesis of lysozyme and nitric oxide 期刊论文 Zheng Yan;Liu Zhaoqun;Wang Lingling;Li Meijia;Zhang Yukun;Zong Yanan;Li Yinan;Song Linsheng
9 Metabolomic and transcriptomic profiling reveals the alteration of energy metabolism in oyster larvae during initial shell formation and under experimental ocean acidification 期刊论文 Liu Zhaoqun;Zhang Yukun;Zhou Zhi;Zong Yanan;Zheng Yan;Liu Chang;Kong Ning;Gao Qiang;Wang Lingling;Song Linsheng
10 A membrane-bound dopamine beta-hydroxylase highly expressed in granulocyte of Pacific oyster Crassostrea gigas 期刊论文 Li Meijia;Dong Miren;Wang Weilin;Li Huan;Liu Zhaoqun;Wang Lingling;Wang Kejian;Song Linsheng
11 A C1qDC (CgC1qDC-6) with a collagen-like domain mediates hemocyte phagocytosis and migration in oysters 期刊论文 Li Huan;Kong Ning;Sun Jiejie;Wang Weilin;Li Meijia;Gong Changhao;Dong Miren;Wang Min;Wang Lingling;Song Linsheng
12 A novel caspase-associated recruitment domain (CARD) containing protein (CgCARDCP-1) involved in LPS recognition and NF-kappa B activation in oyster (Crassostrea gigas) 期刊论文 Wang Feifei;Yu Zichao;Wang Weilin;Li Yiqun;Lu Guangxia;Qu Chen;Wang Hui;Lu Mengmeng;Wang Lingling;Song Linsheng
13 A novel programmed cell death protein 4 negatively regulates CgIL17-5 expression in hemocytes of oyster Pacific oyster (Crassostrea gigas) 期刊论文 Yan Yunchen;Wang Weilin;Liu Zhaoqun;Lv Xiaojing;Li Meijia;Yang Wen;Wang Lingling;Song Linsheng
14 A DM9-containing protein from oyster Crassostrea gigas (CgDM9CP-3) mediating immune recognition and encapsulation 期刊论文 Liu Yu;Wang Weilin;Zhao Qi;Yuan Pei;Li Jiaxin;Song Xiaorui;Liu Zhaoqun;Ding Dewen;Wang Lingling;Song Linsheng
15 DNA binding protein CgIkaros-like regulates the proliferation of agranulocytes and granulocytes in oyster (Crassostrea gigas) 期刊论文 Sun Wending;Song Xiaorui;Dong Miren;Liu Zhuyun;Song Ying;Wang Lingling;Song Linsheng
16 Digging into bivalve miRNAomes: between conservation and innovation 期刊论文 Rosani Umberto;Bortoletto Enrico;Bai Changming;Novoa Beatriz;Figueras Antonio;Venier Paola;Fromm Bastian
17 The cGAS/STING-TBK1-IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster 期刊论文 Qiao Xue;Zong Yanan;Liu Zhaoqun;Wu Zhaojun;Li Yuanmei;Wang Lingling;Song Linsheng
18 The increased expression of an engrailed to sustain shell formation in response to ocean acidification 期刊论文 Zhang Yukun;Liu Zhaoqun;Zong Yanan;Zheng Yan;Li Yinan;Han Zirong;Wang Lingling;Song Linsheng
19 The unfolded protein response signaling pathways in molluscs 期刊论文 Huang Yuting;Sun Jiejie;Wang Lingling;Song Linsheng
20 The Dicer from oyster Crassostrea gigas functions as an intracellular recognition molecule and effector in anti-viral immunity 期刊论文 Lv Xiaojing;Wang Weilin;Han Zirong;Liu Shujing;Yang Wen;Li Meijia;Wang Lingling;Song Linsheng
21 The transformation of energy metabolism and Endoplasmic Reticulum stress regulation in Pacific oyster Crassostrea gigas under air exposure 期刊论文 Gong Changhao;Liu Chang;Li Huan;Li Meijia;Liu Zhaoqun;Wang Weilin;Wang Lingling;Song Linsheng
22 CgCLec-HTM-Mediated Signaling Pathway Regulates Lipopolysaccharide-Induced CgIL-17 and CgTNF Production in Oyster 期刊论文 Sun Jiejie;Wang Lingling;Huang Mengmeng;Li Yinan;Wang Weilin;Song Linsheng
23 Molecular characterization of a cathepsin L1 highly expressed in phagocytes of pacific oyster Crassostrea gigas 期刊论文 Lv Zhao;Qiu Limei;Liu Zhaoqun;Wang Weilin;Chen Hao;Jia Yunke;Jia Zhihao;Jiang Shuai;Wang Lingling;Song Linsheng
24 CgNrdp1, a conserved negative regulating factor of MyD88-dependent Toll like receptor signaling in oyster Crassostrea gigas 期刊论文 Sun Rui;Qiu Limei;Yi Qilin;Wang Mengqiang;Yue Feng;Wang Lingling;Song Linsheng
25 The transcriptomic expression of pattern recognition receptors: Insight into molecular recognition of various invading pathogens in Oyster Crassostrea gigas 期刊论文 Wang Lingling;Zhang Huan;Wang Mengqiang;Zhou Zhi;Wang Weilin;Liu Rui;Huang Mengmeng;Yang Chuanyan;Qiu Limei;Song Linsheng
26 Identification of a Novel Pattern Recognition Receptor DM9 Domain Containing Protein 4 as a Marker for Pro-Hemocyte of Pacific Oyster Crassostrea gigas 期刊论文 Jia Zhihao;Jiang Shuai;Wang Mengqiang;Wang Xiudan;Liu Yu;Lv Zhao;Song Xiaorui;Li Yiqun;Wang Lingling;Song Linsheng
27 A hexokinase from the oyster Crassostrea gigas is involved in immune recognition as a pattern recognition receptor 期刊论文 Chen Xiaowei;Liu Zhaoqun;Gu Yifan;Zhang Yukun;Liu Yu;Wang Lingling;Song Linsheng
28 A Signaling Pathway to Mediate the Combined Immunomodulation of Acetylcholine and Enkephalin in Oyster Crassostrea gigas 期刊论文 Liu Zhaoqun;Zhou Zhi;Wang Lingling;Zhang Yukun;Zong Yanan;Zheng Yan;Li Meijia;Wang Weilin;Song Linsheng
29 An Ancient BCR-like Signaling Promotes ICP Production and Hemocyte Phagocytosis in Oyster 期刊论文 Sun Jiejie;Wang Lingling;Yang Chuanyan;Song Linsheng
30 Protein kinase-like ER kinase (PERK) regulates autophagy of hemocytes in antiviral immunity of Pacific oyster Crassostrea gigas 期刊论文 Liu Shujing;Wang Weilin;Liu Yu;Cao Wanqing;Yuan Pei;Li Jiaxin;Song Xiaorui;Wang Lingling;Song Linsheng
31 A conserved interferon regulation factor 1 (IRF-1) from Pacific oyster Crassostrea gigas functioned as an activator of IFN pathway 期刊论文 Lu Mengmeng;Yang Chuanyan;Li Meijia;Yi Qilin;Lu Guangxia;Wu Yichen;Qu Chen;Wang Lingling;Song Linsheng
32 Ostreid Herpesvirus-1 Infects Specific Hemocytes in Ark Clam, Scapharca broughtonii 期刊论文 Xin Lusheng;Li Chen;Bai Changming;Wang Chongming
33 A fibrinogen-related protein mediates the recognition of various bacteria and haemocyte phagocytosis in oyster Crassostrea gigas 期刊论文 Yang Wenwen;Lv Xiaoqian;Leng Jinyuan;Li Yinan;Sun Jiejie;Yang Chuanyan;Wang Lingling;Song Linsheng
34 The cholinergic and adrenergic autocrine signaling Pathway Mediates immunomodulation in Oyster Crassostrea gigas 期刊论文 Liu Zhaoqun;Wang Lingling;Lv Zhao;Zhou Zhi;Wang Weilin;Li Meijia;Yi Qilin;Qiu Limei;Song Linsheng
35 The activated beta-integrin (Cg beta V) enhances RGD-binding and phagocytic capabilities of hemocytes in Crassostrea gigas 期刊论文 Lv Zhao;Qiu Limei;Jia Zhihao;Wang Weilin;Liu Zhaoqun;Wang Lingling;Song Linsheng
36 CgSOCS6 negatively regulates the expression of CgIL17s and CgDefh1 in the pacific oyster Crassostrea gigas 期刊论文 Wu Zhaojun;Sun Jiejie;Wang Liyan;Zong Yanan;Han Zirong;Yang Wen;Liu Zhaoqun;Wang Lingling;Song Linsheng
37 ATG10 (autophagy-related 10) regulates the formation of autophagosome in the anti-virus immune response of pacific oyster (Crassostrea gigas) 期刊论文 Han Zirong;Wang Weilin;Lv Xiaojing;Zong Yanan;Liu Shujing;Liu Zhaoqun;Wang Lingling;Song Linsheng
38 OsHV-1 infection leads to mollusc tissue lesion and iron redistribution, revealing a strategy of iron limitation against pathogen 期刊论文 Xin Lusheng;Huang Bowen;Zhang Huan;Li Chen;Bai Changming;Wang Chongming
39 长牡蛎含DM9结构域重组蛋白rCgDM9CP-6、制备方法及应用 专利 王玲玲;李奕男;孙洁洁;王伟林;宋林生
40 An HECT domain ubiquitin ligase CgWWP1 regulates granulocytes proliferation in oyster Crassostrea gigas 期刊论文 Song Ying;Song Xiaorui;Zhang Dan;Yang Ying;Wang Lingling;Song Linsheng
41 Ca2+/Calmodulin-NOS/NO-TNFs pathway hallmarks the inflammation response of oyster during aerial exposure 期刊论文 Chen Hao;Xin Lusheng;Wang Lin;Zhang Huan;Liu Rui;Wang Hao;Qiao Xue;Wang Lingling;Song Linsheng
42 IgIT-Mediated Signaling Inhibits the Antimicrobial Immune Response in Oyster Hemocytes 期刊论文 Sun Jiejie;Wang Lingling;Yang Wenwen;Wang Liyan;Fu Qiang;Song Linsheng
43 A novel Adiponectin receptor (AdipoR) involved in regulating cytokines production and apoptosis of haemocytes in oyster Crassostrea gigas 期刊论文 Ge Wenjing;Huang Shu;Liu Shujing;Sun Jiejie;Liu Zhaoqun;Yang Wenwen;Wang Lingling;Song Linsheng
44 Hemolymph C1qDC promotes the phagocytosis of oyster Crassostrea gigas hemocytes by interacting with the membrane receptor beta-integrin 期刊论文 Lv Zhao;Wang Lingling;Jia Zhihao;Sun Jiejie;Wang Weilin;Liu Zhaoqun;Qiu Limei;Wang Mengqiang;Song Linsheng
45 A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks 期刊论文 Rosani Umberto;Bai Chang-Ming;Maso Lorenzo;Shapiro Maxwell;Abbadi Miriam;Domeneghetti Stefania;Wang Chong-Ming;Cendron Laura;MacCarthy Thomas;Venier Paola
46 D1 dopamine receptor is involved in shell formation in larvae of Pacific oyster Crassostrea gigas 期刊论文 Liu Zhaoqun;Wang Lingling;Yan Yunchen;Zheng Yan;Ge Wenjing;Li Meijia;Wang Weilin;Song Xiaorui;Song Linsheng
47 CgAATase with specific expression pattern can be used as a potential surface marker for oyster granulocytes 期刊论文 Dong Miren;Song Xiaorui;Wang Min;Wang Weilin;Zhang Peng;Liu Yu;Li Meijia;Wang Lingling;Song Linsheng
48 A single-CRD C-type lectin (CgCLec-3) with novel DIN motif exhibits versatile immune functions in Crassostrea gigas 期刊论文 Song Xiaorui;Xin Xiaoyu;Wang Hao;Li Hui;Zhang Huan;Jia Zhihao;Liu Conghui;Jiang Shuai;Wang Lingling;Song Linsheng
49 The sensing pattern and antitoxic response of Crassostrea gigas against extracellular products of Vibrio splendidus 期刊论文 Wang Weilin;Lv Xiaojing;Liu Zhaoqun;Song Xiaorui;Yi Qilin;Wang Lingling;Song Linsheng
50 A calmodulin targeted by miRNA scaffold659_26519 regulates IL-17 expression in the early immune response of oyster Crassostrea gigas 期刊论文 Han Zirong;Li Jialuo;Wang Weilin;Li Jiaxin;Zhao Qi;Li Meijia;Wang Lingling;Song Linsheng
51 AP-1 regulates the expression of IL17-4 and IL17-5 in the pacific oyster Crassostrea gigas 期刊论文 Wang Liyan;Sun Jiejie;Wu Zhaojun;Lian Xingye;Han Shuo;Huang Shu;Yang Chuanyan;Wang Lingling;Song Linsheng
52 Viral Decoys: The Only Two Herpesviruses Infecting Invertebrates Evolved Different Transcriptional Strategies to Deflect Post-Transcriptional Editing 期刊论文 Bai Changming;Rosani Umberto;Zhang Xiang;Xin Lusheng;Bortoletto Enrico;Wegner Mathias;Wang Chongming
53 The involvement of PyBeclin 1 and PyLC3 in regulating the activation of autophagy in scallop Patinopecten yessoensis after acute high temperature stress 期刊论文 Shan Ying;Yang Chuanyan;Guo Xiaoxiao;Sun Jiejie;He Zhaoyu;Jiang Dongli;Yang Wenwen;Wang Lingling;Song Linsheng
54 A CD63 Homolog Specially Recruited to the Fungi-Contained Phagosomes Is Involved in the Cellular Immune Response of OysterCrassostrea gigas 期刊论文 Liu Conghui;Yang Chuanyan;Wang Mengqiang;Jiang Shuai;Yi Qilin;Wang Weilin;Wang Lingling;Song Linsheng
55 水产无脊椎动物免疫识别的分子机制 奖励 宋林生;张 峘;王玲玲;邱丽梅;宋小瑞;姜 帅
56 The involvement of a regucalcin in suppressing hemocyte apoptosis in Pacific oyster Crassostrea gigas 期刊论文 Lian Xingye;Huang Shu;Han Shuo;Yi Qilin;Wang Weilin;Sun Jiejie;Wang Lingling;Song Linsheng
57 The antifungal activity of a thaumatin-like protein from oyster Crassostrea gigas 期刊论文 Niu Xuming;Xu Qingsong;Wang Weilin;Yu Zichao;Liu Zhaoqun;Qu Chen;Liu Yu;Gong Changhao;Wang Lingling;Song Linsheng
58 A SPRY domain-containing SOCS box protein 3 (SPSB3) involved in the regulation of cytokine production in granulocytes of Crassostrea gigas 期刊论文 Wang Min;Liu Chang;Wang Weilin;Dong Miren;Zhang Peng;Liu Yu;Wang Lingling;Song Linsheng
59 A hypervariable immunoglobulin superfamily member from Crassostrea gigas functions as pattern recognition receptor with opsonic activity 期刊论文 Liu Dongyang;Yi Qilin;Wu Yichen;Lu Guangxia;Gong Changhao;Song Xiaorui;Sun Jiejie;Qu Chen;Liu Conghui;Wang Lingling;Song Linsheng
60 Long-range PCR and high-throughput sequencing of Ostreid herpesvirus 1 indicate high genetic diversity and complex evolution process 期刊论文 Bai Chang-Ming;Morga Benjamin;Rosani Umberto;Shi Jie;Li Chen;Xin Lu-Sheng;Wang Chong-Ming
61 The Inhibition of Ocean Acidification on the Formation of Oyster Calcified Shell by Regulating the Expression of Cgchs1 and Cgchit4 期刊论文 Zhang Yukun;Liu Zhaoqun;Song Xiaorui;Huang Shu;Wang Lingling;Song Linsheng
62 A vital ubiquitin-conjugating enzyme CgUbe2g1 participated in regulation of immune response of Pacific oyster Crassostrea gigas 期刊论文 Liu Rui;Cheng Qi;Song Xiaorui;Wang Hao;Wang Xiudan;Wang Lingling;Zhu Beiwei;Song Linsheng
63 The involvement of TLR signaling and anti-bacterial effectors in enhanced immune protection of oysters after Vibrio splendidus pre-exposure 期刊论文 Wang Weilin;Wang Lingling;Liu Zhaoqun;Song Xiaorui;Yi Qilin;Yang Chuanyan;Song Linsheng
64 The immunomodulatory function of invertebrate specific neuropeptide FMRFamide in oyster Crassostrea gigas 期刊论文 Li Meijia;Wang Min;Wang Weilin;Wang Lingling;Liu Zhaoqun;Sun Jiejie;Wang Kejian;Song Linsheng
65 A haemocyte-expressed Methyltransf_FA domain containing protein (MFCP) exhibiting microbe binding activity in oyster Crassostrea gigas 期刊论文 Li Jiaxin;Wang Weilin;Zhao Qi;Fan Siqi;Li Yan;Yuan Pei;Wang Lingling;Song Linsheng
66 The characterization of an interleukin-12 p35 homolog involved in the immune modulation of oyster Crassostrea gigas 期刊论文 Xin Lusheng;Liu Chang;Zhang Huan;Qiu Limei;Wang Lingling;Song Linsheng
67 Isolation and Characterization of Vibrio kanaloae as a Major Pathogen Associated with Mass Mortalities of Ark Clam, Scapharca broughtonii, in Cold Season. 期刊论文 Huang Bowen;Zhang Xiang;Wang Chongming;Bai Changming;Li Chen;Li Chenghua;Xin Lusheng
68 The DNA cytosine-5-methyltransferase 3 (DNMT3) involved in regulation of CgIL-17 expression in the immune response of oyster Crassostrea gigas 期刊论文 Zhao Qi;Wang Weilin;Li Jia Xin;Yuan Pei;Liu Yu;Li Yan;Wang Lingling;Song Linsheng
69 The glutaminase (CgGLS-1) mediates anti-bacterial immunity by prompting cytokine synthesis and hemocyte apoptosis in Pacific oyster Crassostrea gigas 期刊论文 Liang Yage;Li Meijia;Liu Zhaoqun;Li Yuanmei;Wang Lingling;Song Linsheng
70 The primitive interferon-like system and its antiviral function in molluscs 期刊论文 Qiao Xue;Wang Lingling;Song Linsheng
71 数字PCR检测长牡蛎白细胞介素17-5基因表达量的引物及探针 专利 王玲玲;刘兆群;王伟林;宋林生;张玉坤
72 CgRel involved in antibacterial immunity by regulating the production of CgIL17s and CgBigDef1 in the Pacific oyster Crassostrea gigas 期刊论文 Li Yinan;Sun Jiejie;Zhang Yukun;Wang Min;Wang Lingling;Song Linsheng
73 An activating transcription factor 6 beta (ATF6 beta) regulates apoptosis of hemocyte during immune response in Crassostrea gigas 期刊论文 Liu Shujing;Wang Weilin;Ge Wenjing;Lv Xiaojing;Han Zirong;Li Yinan;Wang Lingling;Song Linsheng
74 海水贝类养殖环境预测预警与信息服务技术 奖励 宋林生;王玲玲;宋 军;张瑞瑾;于子超;李华江;张 薇;张 媛;宣基亮;汤 勇;于 红;田 涛;郭俊如;尹远渊;王 刚;富砚昭;徐江玲;刘 奇;方 蕾;张 燕
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