基于CRISPR文库筛查技术的绒山羊毛囊干细胞增殖必需基因鉴定及功能研究
31772571
2017
C1702.家畜种质资源与遗传育种学
王小龙
面上项目
教授
西北农林科技大学
60万元
羊;绒山羊;基因功能;次级毛囊;基因定位
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling | 期刊论文 | Li Chao;Li Yan;Zhou Guangxian;Gao Ye;Ma Sen;Chen Yulin;Song Jiuzhou;Wang Xiaolong |
| 2 | Cytosine and adenine deaminase base-editors induce broad and nonspecific changes in gene expression and splicing | 期刊论文 | Fan Jiao;Ding Yige;Ren Chaoi;Song Ziguo;Yuan Jie;Chen Qiuzhen;Du chenchen;Li Chao;Wang Xiaolong;Shu Wenjie |
| 3 | Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep | 期刊论文 | Wang Xiaolong;Liu Jing;Niu Yiyuan;Li Yan;Zhou Shiwei;Li Chao;Ma Baohua;Kou Qifang;Petersen Bjoern;Sonstegard Tad;Huang Xingxu;Jiang Yu;Chen Yulin |
| 4 | Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats | 期刊论文 | Li Chao;Zhou Shiwei;Li Yan;Li Guanwei;Ding Yige;Li lan;Liu Jing;Qu Lei;Sonstegard Tad;Huang Xingxu;Jiang Yu;Chen Yulin;Peteren Bjoern;Wang Xiaolong |
| 5 | More abundant and healthier meat: Will the MSTN editing epitome empower the commercialization of gene editing in livestock? | 期刊论文 | Wang Xiaolong;Petersen Björn |
| 6 | Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation | 期刊论文 | Yan Hailong;Gao Ye;Ding Qiang;Liu Jiao;Li Yan;Jin Miaohan;Xu Han;Ma Sen;Wang Xiaolong;Zeng Wenxian;Chen Yulin |
| 7 | Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair | 期刊论文 | Li Guanwei;Zhou Shiwei;Li Chao;Cai Bei;Yu Honghao;Ma Baohua;Huang Yu;Ding Yige;Liu Yao;Ding Qiang;He Chong;Zhou Jiankui;Wang Ying;Zhou Guangxian;Li Yan;Yan Yuan;Hua Jinlian;Petersen Bjoern;Jiang Yu;Sonstegard Tad;Huang Xingxu;Chen Yulin;Wang Xiaolong |
| 8 | Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats | 期刊论文 | Li Yan;Zhou Guangxian;Zhang Rui;Guo Jiazhong;Li Chao;Martin Graeme;Chen Yulin;Wang Xiaolong |
| 9 | Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats | 期刊论文 | Zhou Guangxian;Kang Danju;Ma Sen;Wang Xingtao;Gao Ye;Yang Yuxin;Wang Xiaolong;Chen Yulin |
| 10 | Efficient generation of mouse models with the prime editing system | 期刊论文 | Liu Yao;Li Xiangyang;He Siting;Huang Shuhong;Li Chao;Chen Yulin;Liu Zhen;Huang Xingxu;Wang Xiaolong |
| 11 | Redesigning small ruminant genomes with CRISPR toolkit: Overview and perspectives | 期刊论文 | Kalds Peter;Gao Yawei;Zhou Shiwei;Cai Bei;Huang Xingxu;Wang Xiaolong;Chen Yulin |
| 12 | Transactivation of miR-202-5p by Steroidogenic Factor 1 (SF1) Induces Apoptosis in Goat Granulosa Cells by Targeting TGF beta R2 | 期刊论文 | Ding Qiang;Jin Miaohan;Wang Yaoyue;Liu Jiao;Kalds Peter;Wang Ying;Yang Yuxin;Wang Xiaolong;Chen Yulin |
| 13 | Enhancing prime editing by Csy4-mediated processing of pegRNA | 期刊论文 | Liu Yao;Yang Guang;Huang Shuhong;Li Xiangyang;Wang Xin;Li Guanglei;Chi Tian;Chen Yulin;Huang Xingxu;Wang Xiaolong |
| 14 | 四种单碱基编辑器在羊成纤维细胞上的编辑效率 | 期刊论文 | 孙嘉媛;孙珂欣;丁一格;周世卫;高亚伟;陈玉林;王小龙 |
| 15 | Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats | 期刊论文 | Ma Sen;Wang Ying;Zhou Guangxian;Ding Yi;Yang Yuxin;Wang Xiaolong;Zhang Enping;Chen Yulin |
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