转录因子Otx2调控猪干细胞多能状态和启动胚层分化的分子机制

31571521
2015
C1201.干细胞基础研究
王华岩
面上项目
教授
西北农林科技大学
60万元
信号通路;细胞重编程;原始态多能性;转录因子;猪
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Characterization of novel alternative splicing variants of Oct4 gene expressed in mouse pluripotent stem cells 期刊论文 Liu Xiaopeng;Yu Tong;Sun Yuxin;Wang Huayan
2 Common microRNA-mRNA interactions exist among distinct porcine iPSC lines independent of their metastable pluripotent states 期刊论文 Zhang Shiqiang;Xie Youlong;Cao Hongxia;Wang Huayan
3 Molecular network of miR-1343 regulates the pluripotency of porcine pluripotent stem cells via repressing OTX2 expression 期刊论文 Xie Youlong;Cao Hongxia;Zhang Zhiyi;Zhang Shiqiang;Wang Huayan
4 Activin-SMAD signaling is required for maintenance of porcine iPS cell self-renewal through upregulation of NANOG and OCT4 expression 期刊论文 Yang Fan;Wang Ning;Wang Yaxian;Yu Tong;Wang Huayan
5 一种建立人多能干细胞诱导分化为成熟血细胞的方法 专利 王华岩;卢世江;王宁
6 The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation 期刊论文 Zhang Jinglong;Cao Hongxia;Xie Jing;Fan Chen;Xie Youlong;He Xin;Liao Mingzhi;Zhang Shiqiang;Wang Huayan
7 ESRRB plays a crucial role in the promotion of porcine cell reprograming. 期刊论文 Fan Yang;Yahui Ren;Huan Li;Huayan Wang
8 Preserving self-renewal of porcine pluripotent stem cells in serum-free 3i culture condition and independent of LIF and b-FGF cytokines. 期刊论文 Yangyang Ma;Tong Yu;Huayan Wang
9 层粘连蛋白基因家族在猪多能干细胞中的表达谱分析 期刊论文 李焕;于童;马洋洋;王华岩
10 EpCAM Intracellular Domain Promotes Porcine Cell Reprogramming by Upregulation of Pluripotent Gene Expression via Beta-catenin Signaling. 期刊论文 Tong Yu;Yangyang Ma;Huayan Wang
11 METTL3对猪干细胞多能基因表达的调控作用 期刊论文 马子玉;任亚辉;凌敏;王华岩
12 OTX2 Impedes Self-renewal of Porcine iPS Cells through Downregulation of NANOG Expression 期刊论文 Ning Wang;Yaxian Wang;Youlong Xie;Huayan Wang
13 猪卵巢颗粒细胞培养及其OCT4表达研究 期刊论文 刘晓鹏;王华岩
14 Sall4表达调控及其启动子核心调控区的筛选 期刊论文 王亚娴;杨藩;王华岩
15 SALL4 maintains self-renewal of porcine pluripotent stem cells through downregulation of OTX2. 期刊论文 Ning Wang;Sile Wang;Yaxian Wang;Yuanxing Cai;Fan Yang;Huayan Wang
16 Methanol fixed fibroblasts serve as feeder cells to maintain stem cells in the pluripotent state in vitro 期刊论文 Ren Yahui;Ma Ziyu;Yu Tong;Ling Min;Wang Huayan
17 一种饲养层细胞及其制备方法与应用 专利 王华岩;任亚辉
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