基于生物分子的PD-L1siRNA多功能纳米递送体系用于小细胞肺癌靶向成像及免疫治疗研究

21877031
2018
B0706.药物化学生物学
刘艳岚
面上项目
教授
湖南大学
67万元
传输;分子识别;多功能纳米载体;RNA干扰技术;免疫治疗
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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1 Spatially Confined Intervention of Cellular Senescence by a Lysosomal Metabolism Targeting Molecular Prodrug for BroadSpectrum Senotherapy 期刊论文 Xia Yinghao;Li Jili;Wang Linlin;Luo Xiyuan;Xie Yuqi;Liu Yanlan
2 Decoding the Complex Free Radical Cascade by Using a DNA Framework-Based Artificial DNA Encoder 期刊论文 Lili Zhang;Linlin Wang;Xi Yuan;Minjuan Zhong;Hong Chen;Dailiang Zhang;Xiaoyan Han;Sitao Xie;Lei He;Yazhou Li;Fengming Chen;Yanlan Liu;Weihong Tan
3 PD-L1抑制剂在制备药物或试剂盒中的用途 专利 谭蔚泓;刘艳岚;韩小燕
4 ADIPOCYTE-TARGETING DNA NANODRUG AND PREPARATION AND USES THEREOF 专利 Weihong Tan;Yanlan Liu;Lili Zhang
5 Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T‑Cell-Independent Cancer Treatment 期刊论文 Xiaoyan Han;Linlin Wang;Ting Li;Jiahui Zhang;Dailiang Zhang;Jili Li;Yinghao Xia;Yanlan Liu;Weihong Tan
6 Stimulus-responsive nanomaterials containing logic gates for biomedical applications 期刊论文 Can Luo;Lei He;Fengming Chen;Ting Fu;Penghui Zhang;Zeyu Xiao;Yanlan Liu;Weihong Tan
7 Molecular Self-assembly of Bioorthogonal Aptamer-Prodrug Conju-gate Micelles for Hydrogen Peroxide and pH-Independent Cancer Chemodynamic Therapy 期刊论文 Wenjing Xuan;Yinghao Xia;Ting Li;Linlin Wang;Yanlan Liu;Weihong Tan
8 Oxygen Vacancy-Driven Reversible Free Radical Catalysis for Environment-Adaptive Cancer Chemodynamic Therapy 期刊论文 Xi Yuan;Linlin Wang;Miaomiao Hu;Lili Zhang;Hong Chen;Dailiang Zhang;Zhimin Wang;Ting Li;Minjuan Zhong;Liujun Xu;Dan Wang;Yanlan Liu;Weihong Tan
9 一种基于铁和多巴胺配位的纳米颗粒光热转换材料及其制备方法和应用 专利 游常军;刘艳岚;孔维恒
10 Sequential module coordination-driven programmable function switch of metal-molecule nanoframeworks for cancer theranostics 期刊论文 Weiheng Kong;Linlin Wang;Yan Zhao;Hong Chen;Yunming Liu;Xiaoyan Han;Ying Yang;Juan Wang;Changjun You;Yanlan Liu
11 Recent Advances in Strategies for Imaging Detection and Intervention of Cellular Senescence 期刊论文 Jili Li;Zhengyan Bi;Linlin Wang;Yinghao Xia;Yuqi Xie;Yanlan Liu
12 Artificial Nucleobase-Directed Programmable Synthesis and Assembly of Amphiphilic Nucleic Acids as an All-in-One Platform for Cation-Free siRNA Delivery 期刊论文 Can Luo;Yuqi Xie;Minze He;Yinghao Xia;Yazhou Li;Lei He;Jili Li;Linlin Wang;Xiaoyan Han;Lili Zhang;Xi Yuan;Zhiqiang Wang;Yanlan Liu;Weihong Tan
13 Engineering AND-Gate Aptamer-Signal Base Conjugates for Targeted Magnetic Resonance Molecular Imaging of Metastatic Cancer 期刊论文 Yazhou Li;Ting Li;Hong Chen;Linlin Wang;Yinghao Xia;Lili Zhang;Yuqi Xie;Jili Li;Can Luo;Yingjie Xu;Yanlan Liu;Weihong Tan
14 一种脂肪细胞靶向的DNA纳米药物及其制备方法与应用 专利 谭蔚泓;刘艳岚;张丽丽
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