铜绿假单胞菌毒素-抗毒素系统HigB-HigA对三型分泌系统的调控机制研究
31670130
2016
C0108.病原细菌学
吴卫辉
面上项目
教授
南开大学
60万元
毒素-抗毒素系统;基因调控;铜绿假单胞菌;持留菌;三型分泌系统
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | In vivo Host Environment Alters Pseudomonas aeruginosa Susceptibility to Aminoglycoside Antibiotics | 期刊论文 | Pan Xiaolei;Dong Yuanyuan;Fan Zheng;Liu Chang;Xia Bin;Shi Jing;Bai Fang;Jin Yongxin;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 2 | HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in Pseudomonas aeruginosa | 期刊论文 | Zhang Yueying;Xia Bin;Li Mei;Shi Jing;Long Yuqing;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 3 | HigB of Pseudomonas aeruginosa Enhances Killing of Phagocytes by Up-Regulating the Type Ill Secretion System in Ciprofloxacin Induced Persister Cells | 期刊论文 | Li Mei;Long Yuqing;Liu Ying;Liu Yang;Chen Ronghao;Shi Jing;Zhang Lu;Jin Yongxin;Yang Liang;Bai Fang;Jin Shouguang;Cheng Zhihui;Wu Weihui |
| 4 | PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids. | 期刊论文 | Pan Xiaolei;Fan Zheng;Chen Lei;Liu Chang;Bai Fang;Wei Yu;Tian Zhenyang;Dong Yuanyuan;Shi Jing;Chen Hao;Jin Yongxin;Cheng Zhihui;Jin Shouguang;Lin Jianping;Wu Weihui |
| 5 | Pseudomonas aeruginosa Polynucleotide Phosphorylase Contributes to Ciprofloxacin Resistance by Regulating PrtR | 期刊论文 | Fan Zheng;Chen Hao;Li Mei;Pan Xiaolei;Fu Weixin;Ren Huan;Chen Ronghao;Bai Fang;Jin Yongxin;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 6 | TpiA is a Key Metabolic Enzyme That Affects Virulence and Resistance to Aminoglycoside Antibiotics through CrcZ in Pseudomonas aeruginosa. | 期刊论文 | Xia Yushan;Wang Dan;Pan Xiaolei;Xia Bin;Weng Yuding;Long Yuqing;Ren Huan;Zhou Jingyi;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 7 | Fis Regulates Type III Secretion System by Influencing the Transcription of exsA in Pseudomonas aeruginosa Strain PA14 | 期刊论文 | Deng Xuan;Li Mei;Pan Xiaolei;Zheng Ruiping;Liu Chang;Chen Fei;Liu Xue;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 8 | Pseudomonas aeruginosa Oligoribonuclease Contributes to Tolerance to Ciprofloxacin by Regulating Pyocin Biosynthesis | 期刊论文 | Chen Fei;Chen Gukui;Liu Yiwei;Jin Yongxin;Cheng Zhihui;Liu Yang;Yang Liang;Jin Shouguang;Wu Weihui |
| 9 | Combination of Azithromycin and Gentamicin for Efficient Treatment of Pseudomonas aeruginosa Infections | 期刊论文 | Ren Huan;Liu Yiwei;Zhou Jingyi;Long Yuqing;Liu Chang;Xia Bin;Shi Jing;Fan Zheng;Liang Yuying;Chen Shuiping;Xu Jun;Wang Penghua;Zhang Yanhong;Zhu Guangbo;Liu Huimin;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 10 | Identification of a small RNA that directly controls the translation of the quorum sensing signal synthase gene rhlI in Pseudomonas aeruginosa | 期刊论文 | Chen Ronghao;Wei Xueying;Li Zhenpeng;Weng Yuding;Xia Yushan;Ren WenRan;Wang Xiangxiang;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 11 | Pseudomonas aeruginosa ExsA Regulates a Metalloprotease, ImpA, That Inhibits Phagocytosis of Macrophages | 期刊论文 | Tian Zhenyang;Cheng Sen;Xia Bin;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Liu Xiaoyun;Wu Weihui |
| 12 | PA5470 Counteracts Antimicrobial Effect of Azithromycin by Releasing Stalled Ribosome in Pseudomonas aeruginosa | 期刊论文 | Shi Jing;Liu Yiwei;Zhang Yueying;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 13 | Fis Contributes to Resistance of Pseudomonas aeruginosa to Ciprofloxacin by Regulating Pyocin Synthesis | 期刊论文 | Long Yuqing;Fu Weixin;Wang Su;Deng Xuan;Jin Yongxin;Bai Fang;Cheng Zhihui;Wu Weihui |
| 14 | Mechanisms of RsaL mediated tolerance to ciprofloxacin and carbenicillin in Pseudomonas aeruginosa | 期刊论文 | Fan Zheng;Xu Chang;Pan Xiaolei;Dong Yuanyuan;Ren Huan;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 15 | Identification of novel genes that promote persister formation by repressing transcription and cell division in Pseudomonas aeruginosa | 期刊论文 | Long Yuqing;Fu Weixin;Li Shouyi;Ren Huan;Li Mei;Liu Chang;Zhang Buyu;Xia Yushan;Fan Zheng;Xu Chang;Liu Jianfeng;Jin Yongxin;Bai Fang;Cheng Zhihui;Liu Xiaoyun;Jin Shouguang;Wu Weihui |
| 16 | Endoribonuclease YbeY Is Essential for RNA Processing and Virulence in Pseudomonas aeruginosa | 期刊论文 | Xia Yushan;Weng Yuding;Xu Congjuan;Wang Dan;Pan Xiaolei;Tian Zhenyang;Xia Bin;Li Haozhou;Chen Ronghao;Liu Chang;Jin Yongxin;Bai Fang;Cheng Zhihui;Kuipers Oscar P.;Wu Weihui |
| 17 | Oligoribonuclease Contributes to Tolerance to Aminoglycoside and beta-Lactam Antibiotics by Regulating KatA in Pseudomonas aeruginosa | 期刊论文 | Xia Bin;Li Mei;Tian Zhenyang;Chen Gukui;Liu Chang;Xia Yushan;Jin Yongxin;Bai Fang;Cheng Zhihui;Jin Shouguang;Wu Weihui |
| 18 | Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence | 期刊论文 | Weng Yuding;Chen Fei;Liu Yiwei;Zhao Qiang;Chen Ronghao;Pan Xiaolei;Liu Chang;Cheng Zhihui;Jin Shouguang;Jin Yongxin;Wu Weihui |
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