圆柱瘤蛋白（CYLD）对纺锤体行为的作用和机制研究

31371382
2013
C0703.细胞增殖及细胞周期
李登文
面上项目
教授
南开大学
80万元
纺锤体;圆柱瘤蛋白;中心体;细胞皮层;微管
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CYLD negatively regulates Hippo signaling by limiting Hpo phosphorylation in Drosophila 期刊论文 Chen Yan;Wang Zaizhu;Wang Ping;Li Dengwen;Zhou Jun;Wu Shian
2 Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells 期刊论文 Li Dengwen;Sun Xiaodong;Zhang Linlin;Yan Bing;Xie Songbo;Liu Ruming;Liu Min;Zhou Jun
3 Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150(glued) to the plus ends of astral microtubules 期刊论文 Ran Jie;Luo Youguang;Zhang Yijun;Yang Yang;Chen Miao;Liu Min;Li Dengwen;Zhou Jun
4 Microtubule Stabilization by Mdp3 Is Partially Attributed to Its Modulation of HDAC6 in Addition to Its Association with Tubulin and Microtubules 期刊论文 Tala;Sun Xiaoou;Chen Jie;Zhang Linlin;Liu Ningning;Zhou Jun;Li Dengwen;Liu Min
5 Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region 期刊论文 Zhang Linlin;Qin Juan;Li Yuanyuan;Wang Jian;He Qianqian;Zhou Jun;Liu Min;Li Dengwen
6 Microtubule-associated protein Mdp3 promotes breast cancer growth and metastasis. 期刊论文 Tala;Xie Songbo;Sun Xiaodong;Sun Xiaoou;Ran Jie;Zhang Linlin;Li Dengwen;Liu Min;Bao Gang;Zhou Jun
7 The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization 期刊论文 Xie Songbo;Chen Miao;Gao Siqi;Zhong Tao;Zhou Peng;Li Dengwen;Zhou Jun;Gao Jinmin;Liu Min
8 Identification of novel microtubule-binding proteins by taxol-mediated microtubule stabilization and mass spectrometry analysis 期刊论文 He Xianfei;Liu Zhu;He Qianqian;Qin Juan;Liu Ningning;Zhang Linlin;Li Dengwen;Zhou Jun;Shui Wenqing;Liu Min
9 CYLD coordinates with EB1 to regulate microtubule dynamics and cell migration 期刊论文 Li Dengwen;Gao Jinmin;Yang Yunfan;Sun Lei;Suo Shaojun;Luo Youguang;Shui Wenqing;Zhou Jun;Liu Min
10 UV Irradiation Triggers Cylindromatosis Translocation, Modification, and Degradation in a Proteasome-Independent Manner 期刊论文 Zhou Ping;Hao Ziwei;Wang Xincheng;Gao Jinmin;Li Dengwen;Xie Songbo;Zhang Tong-Cun
11 End-binding protein 1 stimulates paclitaxel sensitivity in breast cancer by promoting its actions toward microtubule assembly and stability 期刊论文 Luo Youguang;Li Dengwen;Ran Jie;Yan Bing;Chen Jie;Dong Xin;Liu Zhu;Liu Ruming;Zhou Jun;Liu Min
12 CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6. 期刊论文 Yang Yunfan;Ran Jie;Liu Min;Li Dengwen;Li Yuanyuan;Shi Xingjuan;Meng Dan;Pan Junmin;Ou Guangshuo;Aneja Ritu;Sun Shao-Cong;Zhou Jun
13 Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization 期刊论文 Xie Songbo;Qin Juan;Liu Shiyu;Zhang Yijun;Wang Jun;Shi Xingjuan;Li Dengwen;Zhou Jun;Liu Min
14 The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly 期刊论文 Xie Wei;Yang Yunfan;Gao Siqi;Song Ting;Wu Yuhan;Li Dengwen;Liu Min;Zhou Jun
15 Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice 期刊论文 Ran Jie;Yu Fan;Qin Juan;Zhang Yijun;Yang Yunfan;Li Dengwen;Zhou Jun;Liu Min
16 Apoptosis-linked gene 2 promotes breast cancer growth and metastasis by regulating the cytoskeleton 期刊论文 Qin Juan;Li Dengwen;Zhou Yunqiang;Xie Songbo;Du Xin;Hao Ziwei;Liu Ruming;Liu Xinqi;Liu Min;Zhou Jun
17 Identification of a Role for the PI3K/AKT/mTOR Signaling Pathway in Innate Immune Cells 期刊论文 Xie Songbo;Chen Miao;Yan Bing;He Xianfei;Chen Xiwen;Li Dengwen
18 CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation 期刊论文 Yang Yunfan;Liu Min;Li Dengwen;Ran Jie;Gao Jinmin;Suo Shaojun;Sun Shao-Cong;Zhou Jun
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