应用PB/PK及PK/PD同步模型研究黏菌素与盐酸小檗碱联合抗鸡多重耐药大肠杆菌作用及种间外推的探讨

31802241
2018
C1808.兽医药物学与毒理学
陈春丽
青年科学基金项目
副教授
东北农业大学
25万元
药代/药效同步模型;生理药动学模型;药物药效间相互作用;种间外推;家禽
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Baicalin attenuatedMycoplasma gallisepticum-induced immune impairment in chicken bursa of fabricius through modulation of autophagy and inhibited inflammation and apoptosis 期刊论文 Ishfaq Muhammad;Zhang Wei;Liu Yuhao;Wang Jian;Wu Zhiyong;Shah Syed W. A.;Li Rui;Miao Yusong;Chen Chunli;Li Jichang
2 Mycoplasma gallisepticum triggers immune damage in the chicken thymus by activating the TLR-2/MyD88/NF-kappa B signaling pathway and NLRP3 inflammasome 期刊论文 Chen Chunli;Li Jichang;Zhang Wei;Shah Syed Waqas Ali;Ishfaq Muhammad
3 METTL3/m(6)A/miRNA-873-5p Attenuated Oxidative Stress and Apoptosis in Colistin-Induced Kidney Injury by Modulating Keap1/Nrf2 Pathway 期刊论文 Wang Jian;Ishfaq Muhammad;Xu Liang;Xia Chunli;Chen Chunli;Li Jichang
4 Population pharmacokinetics for danofloxacin in the intestinal contents of healthy and infected chickens 期刊论文 Tian Erjie;Chen Chunli;Hu Wanjun;Miao Yusong;Muhammad Ishfaq;Zhang Qiaomei;Liu Yuhao;Xu Liang;Bao Jiaxin;Ding Liangjun;Li Jichang
5 7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway 期刊论文 Wang Jian;Ishfaq Muhammad;Fan Qianqian;Chen Chunli;Li Jichang
6 Colistin induced peripheral neurotoxicity involves mitochondrial dysfunction and oxidative stress in mice 期刊论文 Dai Chongshan;Tang Shusheng;Biao Xiang;Xiao Xilong;Chen Chunli;Li Jichang
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