ApoE/LDLR信号通路抑制流感病毒H3N2诱发COPD急性加重气道炎症风暴分子机制研究

81870036
2018
H0105.慢性阻塞性肺疾病
费广鹤
面上项目
教授
安徽医科大学
60万元
气道炎症风暴;原代气道上皮细胞;COPD急性加重;ApoE/LDLR;流感病毒H3N2
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Melatonin Suppresses Macrophage M1 Polarization and ROS Mediated Pyroptosis via Activating ApoE/LDLR Pathway in Influenza A-Induced Acute Lung Injury 期刊论文 Xu Meng-Meng;Kang Jia-Ying;Ji Shuang;Wei Yuan-Yuan;Wei Si-Liang;Ye Jing-Jing;Wang Yue-Guo;Shen Ji-Long;Wu Hui-Mei;Fei Guang-He
2 新发呼吸道病毒性传染病炎症风暴机制与防治策略研究与临床应用 奖励 费广鹤;吴惠梅;胡先纬;李永怀;涂友慧;季爽;戴梦缘;韦媛媛
3 Interleukin-6 Ab attenuates the hypersecretion of airway mucus via inducing the nuclear translocation of Nrf2 in COPD 会议论文 Wei Yuan-Yuan;Zhang Da-Wei;Fei Guang-He
4 The novel molecular mechanism of cellular energy exhaustion and metabolism reprogramming induced by influenza A virus through OMA1/OPA1 pathway and rescued by melatonin treatment in AECOPD 会议论文 Wei Yuan-Yuan;Zhang Da-Wei;Ye Jing-Jing;Fei Guang-He
5 一种针对COPD患者的原代支气管上皮细胞的分离培养方法 专利 费广鹤;季爽;张仁泉;张大卫;吴旭;任祥春;张文英
6 Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome activation 期刊论文 Ji Shuang;Dai Meng-Yuan;Huang Yun;Ren Xiang-Chun;Jiang Meng-Long;Qiao Jin-Ping;Zhang Wen-Ying;Xu Yuan-Hong;Shen Ji-Long;Zhang Ren-Quan;Fei Guang-He
7 Interleukin-6 neutralizing antibody attenuates the hypersecretion of airway mucus via inducing the nuclear translocation of Nrf2 in chronic obstructive pulmonary disease 期刊论文 Wei Yuan-Yuan;Zhang Da-Wei;Ye Jing-Jing;Lan Qing-Xia;Ji Shuang;Sun Li;Li Fang;Fei Guang-He
8 RKIP suppresses the influenza A virus‑induced airway inflammatory response via the ERK/MAPK pathway 会议论文 Ye Jing-Jing;Wei Si-Liang;Wei Yuan-Yuan;Zhang Da-Wei;Fei Guang-He
9 一种中西药组合物的新用途 专利 费广鹤;季爽;张大卫;吴旭;韦媛媛
10 CD19 and POU2AF1 are Potential Immune-Related Biomarkers Involved in the Emphysema of COPD: On Multiple Microarray Analysis 期刊论文 Zhang Da-Wei;Ye Jing-Jing;Sun Ying;Ji Shuang;Kang Jia-Ying;Wei Yuan-Yuan;Fei Guang-He
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