三阴性乳腺癌代谢标志物筛选、鉴定及蛋白靶向探针可视化研究
91959129
2019
H2808.纳米医学
黄兴禄
重大研究计划
教授
南开大学
84万元
低氧;分子影像;三阴性乳腺癌;铁蛋白;线粒体代谢
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Bioorthogonal catalytic nanozyme-mediated lysosomal membrane leakage for targeted drug delivery | 期刊论文 | Zhiyuan Sun;Qiqi Liu;Xinyue Wang;Jin Wu;Xueyan Hu;Miaomiao Liu;Xiangyun Zhang;Yonghua Wei;Zhijun Liu;Hongjiang Liu;Rui Chen;Fei Wang;Adam C. Midgley;Aitao Li;Xiyun Yan;Yanming Wang;Jie Zhuang;Xinglu Huang |
| 2 | Modular Assembly of Tumor-Penetrating and Oligomeric Nanozyme Based on Intrinsically Self-Assembling Protein Nanocages | 期刊论文 | Liu Qiqi;Tian Jingwei;Liu Jinjian;Zhu Mingsheng;Gao Zhanxia;Hu Xueyan;Midgley Adam C.;Wu Jin;Wang Xinyue;Kong Deling;Zhuang Jie;Liu Jianfeng;Yan Xiyun;Huang Xinglu |
| 3 | Biomimetic Design of Mitochondria-Targeted Hybrid Nanozymes as Superoxide Scavengers | 期刊论文 | Zhang Yue;Khalique Anila;Du Xinchen;Gao Zhanxia;Wu Jin;Zhang Xiangyun;Zhang Ran;Sun Zhiyuan;Liu Qiqi;Xu Zhelong;Midgley Adam C.;Wang Lianyong;Yan Xiyun;Zhuang Jie;Kong Deling;Huang Xinglu |
| 4 | Biomimetic Design of Artificial Hybrid Nanocells for Boosted Vascular Regeneration in Ischemic Tissues | 期刊论文 | Xiangyun Zhang;Yue Zhang;Ran Zhang;Xinbang Jiang;Adam C Midgley;Qiqi Liu;Helong Kang;Jin Wu;Anila Khalique;Meng Qian;Di An;Jing Huang;Lailiang Ou;Qiang Zhao;Jie Zhuang;Xiyun Yan;Deling Kong;Xinglu Huang |
| 5 | A Novel Model System for Understanding Anticancer Activity of Hypoxia-Activated Prodrugs | 期刊论文 | Sun Zhiyuan;Zhang Haoqi;Wu Jin;Gao Fangli;Zhang Congcong;Hu Xueyan;Liu Qiqi;Wei Yonghua;Zhuang Jie;Huang Xinglu |
| 6 | 一种多臂PEG修饰的铁蛋白超分子蛋白载体、制备方法及应用 | 专利 | 黄兴禄;刘奇奇;庄洁 |
| 7 | Combining Doxorubicin-Conjugated Polymeric Nanoparticles and 5-Aminolevulinic Acid for Enhancing Radiotherapy against Lung Cancer | 期刊论文 | Jinghua Han;Wei Yang;Yuanke Li;Jianwen Li;Fangchao Jiang;Jin Xie;Xinglu Huang |
| 8 | Screening of Protein-Based Ultrasmall Nanozymes for Building Cell-Mimicking Catalytic Vesicles | 期刊论文 | Jin Wu;Yonghua Wei;Jingping Lan;Xueyan Hu;Fangli Gao;Xiangyun Zhang;Zhanxia Gao;Qiqi Liu;Zhiyuan Sun;Rui Chen;Hanqing Zhao;Kelong Fan;Xiyun Yan;Jie Zhuang;Xinglu Huang |
| 9 | Targeted Delivery of Nanomedicines for Promoting Vascular Regeneration in Ischemic Diseases | 期刊论文 | Jie Zhuang;Xiangyun Zhang;Qiqi Liu;Mingsheng Zhu;Xinglu Huang |
| 10 | Tumor Cell Nanovaccines based on Genetically Engineered Antibody-anchored Membrane | 期刊论文 | Yuanke Li;Haoqi Zhang;Ruikun Wang;Yuan Wang;Ruonan Li;Mingsheng Zhu;Xiangyun Zhang;Zhen Zhao;Yajuan Wan;Jie Zhuang;Hongkai Zhang;Xinglu Huang |
| 11 | 人工合成钯纳米酶催化含有酚羟基连接的化合物的应用 | 专利 | 黄兴禄;孙志远;庄洁 |
| 12 | Particle-based Artificial Three-dimensional Stem Cell Spheroids for Revascularization of Ischemic Diseases | 期刊论文 | Zhang Ran;Luo Wenya;Zhang Yue;Zhu Dashuai;Midgley Adam C.;Song Hao;Khalique Anila;Zhang Haoqi;Zhuang Jie;Kong Deling;Huang Xinglu |
| 13 | Machine-learning-assisted Single-vessel Analysis of Nanoparticle Permeability in Tumour Vasculatures | 期刊论文 | Mingsheng Zhu;Jie Zhuang;Zhe Li;Qiqi Liu;Rongping Zhao;Zhanxia Gao;Adam C. Midgley;Tianyi Qi;Jingwei tian;Zhixuan Zhang;Deling Kong;Jie Tian;Xiyun Yan;Xinglu Huang |
| 14 | Nanozyme-Powered Giant Unilamellar Vesicles for Mimicry and Modulation of Intracellular Oxidative Stress | 期刊论文 | Hu Xueyan;Wang Xinyue;Liu Qiqi;Wu Jin;Zhang Haoqi;Khalique Anila;Sun Zhiyuan;Chen Rui;Wei Jing;Li Hongbo;Kong Deling;Zhuang Jie;Yan Xiyun;Huang Xinglu |
| 15 | Machine Learning-assisted Nanozyme Design: Lessons from Materials and Engineered Enzymes | 期刊论文 | Jie Zhuang;Adam C. Midgley;Yonghua Wei;Qiqi Liu;Deling Kong;Xinglu Huang |
| 16 | Genetically Engineered Protein Corona-based Cascade Nanozymes for Enhanced Tumor Therapy | 期刊论文 | Zhijun Liu;Qiqi Liu;Haoqi Zhang;Xiangyun Zhang;Jin Wu;Zhiyuan Sun;Mingsheng Zhu;Xueyan Hu;Tianyi Qi;Helong Kang;Rui Chen;Xinglu Huang;Jie Zhuang |
| 17 | 一种吡啶盐改性的含有不同硝基芳杂环的前药小分子 | 专利 | 黄兴禄;孙志远;庄洁 |
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