常温机械灌注系统中HO-1基因修饰的BMMSCs修复DCD供肝的作用及其分子机制研究

81670574
2016
H0311.肝保护和人工肝
宋红丽
面上项目
主任医师
南开大学
58万元
常温机械灌注;心脏死亡捐献;血红素加氧酶-1;骨髓间充质干细胞;缺血-再灌注损伤
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Heme oxygenase-1-modified bone marrow mesenchymal stem cells combined with normothermic machine perfusion to protect donation after circulatory death liver grafts 期刊论文 Huan Cao;Liu Yang;Bin Hou;Dong Sun;Ling Lin;Hong-Li Song;Zhong-Yang Shen
2 一种小动物器官常温机械灌注系统 专利 宋红丽;沈中阳;曹欢
3 Protective effects of heme oxygenase-1-transduced bone marrow-derived mesenchymal stem cells on reduced-size liver transplantation: Role of autophagy regulated by the ERK/mTOR signaling pathway 期刊论文 RAORAO WANG;ZHONGYANG SHEN;LIU YANG;MINGLI YIN;WEIPING ZHENG;BIN WU;TAO LIU;HONGLI SONG
4 MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3 期刊论文 Dong Sun;Huan Cao;Liu Yang;Ling Lin;Bin Hou;Weiping Zheng;Zhongyang Shen;Hongli Song
5 Immunomodulatory effects of bone marrow mesenchymal stem cells overexpressing heme oxygenase-1: Protective effects on acute rejection following reduced-size liver transplantation in a rat model 期刊论文 Zhong-Yang Shen;Bin Wu;Tao Liu;Yang Yang;Ming-Li Yin;Wei-Ping Zheng;Bo-Ya Zhang;Hong-Li Song
6 Effects of heme oxygenase-1-modified bone marrow mesenchymal stem cells on microcirculation and energy metabolism following liver transplantation 期刊论文 Liu Yang;Zhong-Yang Shen;Rao-Rao Wang;Ming-Li Yin;Wei-Ping Zheng;Bin Wu;Tao Liu;Hong-Li Song
7 血红素加氧酶-1修饰的BMMSCs改善大鼠减体积移植肝脏微循环的研究 期刊论文 杨柳;曹欢;孙东;侯宾;沈中阳;宋红丽
8 血红素加氧酶-1增强骨髓间充质干细胞减轻小肠移植排斥反应 期刊论文 杨洋;沈中阳;尹明丽;郑卫萍;刘涛;董冲;宋红丽
9 基因修饰的干细胞保护受损小肠上皮紧密连接 期刊论文 孙东;尹明丽;杨柳;曹欢;杨洋;沈中阳;宋红丽
10 常温机械灌注下大鼠骨髓间充质干细胞修复心脏死亡后捐献供肝 期刊论文 尹明丽;杨洋;史源;杨柳;王绕绕;沈中阳;宋红丽
11 Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers 期刊论文 Liu Yang;Huan Cao;Dong Sun;Ling Lin;Wei-Ping Zheng;Zhong-Yang Shen;Hong-Li Song
12 常温机械灌注联合基因修饰的干细胞修复小动物器官系统 专利 宋红丽;天津市第一中心医院
13 Effect of CXCR3/HO-1 genes modifed bone marrow mesenchymal stem cells on small bowel transplant rejection 期刊论文 Ming-Li Yin;Hong-Li Song;Yang Yang;Wei-Ping Zheng;Tao Liu;Zhong-Yang Shen
14 骨髓间充质干细胞联合常温机械灌注保存大鼠DCD供肝对胆管上皮细胞的影响 期刊论文 侯宾;宋红丽;杨柳;曹欢;孙东;沈中阳
15 Study of the protective effect on damaged intestinal epithelial cells of rat multilineage‐differentiating stress‐enduring (Muse) cells 期刊论文 Dong Sun;Liu Yang;Huan Cao;Zhong‐Yang Shen;Hong‐Li Song
16 HO-1 修饰的 BMMSC 对大鼠小肠移植 免疫功能的影响 期刊论文 宋红丽;杨洋;尹明丽;郑卫萍;刘涛;董冲;沈中阳
17 Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality—the important role of hepatic microcirculation in donation after circulatory death 期刊论文 Liu Yang;Huan Cao;Dong Sun;Bin Hou;Ling Lin;Zhong-Yang Shen;Hong-Li Song
18 优化的常温机械灌注保存大鼠心脏死亡后捐献供肝对移植肝中胆管上皮细胞的作用 期刊论文 侯宾;曹欢;杨柳;孙东;史源;沈中阳;宋红丽
19 Protective effects of CXCR3/HO‑1 gene‑modifed BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway 期刊论文 MINGLI YIN;ZHONGYANG SHEN;LIU YANG;WEIPING ZHENG;HONGLI SONG
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