m6A阅读器蛋白家族YTHDF调控mRNA在轴突内局部翻译和转运的机制研究
31871038
2018
C0902.发育与衰老神经生物学
姬生健
面上项目
研究员
南方科技大学
60万元
核糖核酸修饰;局部蛋白合成;轴突伸长;m6A;轴突
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The m(6)A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons | 期刊论文 | Jun Yu;Yuanchu She;Lixin Yang;Mengru Zhuang;Peng Han;Jianhui Liu;Xiaoyan Lin;Nijia Wang;Mengxian Chen;Chunxuan Jiang;Yujia Zhang;Yujing Yuan;Sheng-Jian Ji |
| 2 | YTHDF2 in dentate gyrus is the m6A reader mediating m6A modification in hippocampus-dependent learning and memory | 期刊论文 | Mengru Zhuang;Xiaoqi Geng;Peng Han;Pengfei Che;Fanghao Liang;Chao Liu;Lixin Yang;Jun Yu;Zhuxia Zhang;Wei Dong;Sheng-Jian Ji |
| 3 | The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells | 期刊论文 | Fugui Niu;Peng Han;Jian Zhang;Yuanchu She;Lixin Yang;Jun Yu;Mengru Zhuang;Kezhen Tang;Yuwei Shi;Baisheng Yang;Chunqiao Liu;Bo Peng;Sheng-Jian Ji |
| 4 | Axonal mRNA localization and translation: local events with broad roles | 期刊论文 | Lichao Li;Jun Yu;Sheng-Jian Ji |
| 5 | 一种用于神经细胞轴突分离培养的多室型微流控装置 | 专利 | 朴宰源;宋惠雪;姚俊伊;姬生健;张建;刘建辉 |
| 6 | m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs | 期刊论文 | Fugui Niu;Pengfei Che;Zhuoxuan Yang;Jian Zhang;Lixin Yang;Mengru Zhuang;Xijun Ou;Sheng-Jian Ji |
| 7 | 用于神经细胞轴突收集及定量分析的微流控芯片 | 专利 | 朴宰源;宋惠雪;姚俊伊;姬生健;张建;刘建辉 |
| 8 | m(6)A Modification in Mammalian Nervous System Development, Functions, Disorders, and Injuries | 期刊论文 | Jun Yu;Yuanchu She;Sheng-Jian Ji |
| 9 | Cbln1 regulates axon growth and guidance in multiple neural regions | 期刊论文 | Peng Han;Yuanchu She;Zhuoxuan Yang;Mengru Zhuang;Qingjun Wang;Xiaopeng Luo;Chaoqun Yin;Junda Zhu;Samie R. Jaffrey;Sheng-Jian Ji |
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