【31072046】β-防御素衍生物的分子设计及生物学活性研究国家自然基金项目

β-防御素衍生物的分子设计及生物学活性研究

项目批准号： 31072046

批准年份： 2010

学科分类： C1706.饲料学

项目负责人：单安山

资助类别：面上项目

负责人职称：教授

依托单位：东北农业大学

资助金额： 35万元

关键词：肉仔鸡;衍生物;分子设计;防御素;生物学活性

起止时间： 2011-01-01到2013-12-31

中英文摘要
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序号	标题	类型	作者
1	利用精氨酸和缬氨酸设计新型α-螺旋抗菌肽(英文)	期刊论文	马清泉\|董娜\|曹艳萍\|单安山\|
2	抗菌肽的功能、研发与应用	期刊论文	单安山\|马得莹\|冯兴军\|马清泉\|董娜\|王良\|吕银凤\|朱鑫\|
3	Biochemical property and in vivo efficacies of novel Val/Arg-rich antimicrobial peptide	期刊论文	QQ Ma\|N Dong\|AS Shan\|L Wang\|WN Hu\|WY Sun\|
4	Strand-Length-Dependent Antimicrobial Activity and Membrane-Active Mechanism of Arginine- and Valine-rich β-Hairpin-like Antimicrobial Peptides	期刊论文	Qingquan Ma\|Na Dong\|Anshan Shan\|Yinfeng Lv\|Wanning Hu\|Yao Gu\|Yuzhi Li\|
5	β-发卡抗菌肽的全新设计及其生物学活性	期刊论文	董娜\|马清泉\|单安山\|曹艳萍\|
6	改良型抗菌肽的研究进展	期刊论文	朱鑫\|马清泉\|董娜\|单安山\|
7	Influence of truncation of avian β-defensin-4 on biological activity and peptide-membrane interaction	期刊论文	Dong N\|Ma QQ\|Shan AS\|Wang L\|Sun W\|Li YZ\|
8	Biochemical property and membrane-peptide interactions of de novo antimicrobial peptides designed by helix-forming units	期刊论文	QQ Ma\|AS Shan\|N Dong\|YF Lv\|YZ Li\|ZH Chen\|BJ Cheng\|ZY Li\|
9	功能性饲料及粗饲料高效利用关键技术研究	奖励	单安山\|
10	一种抗菌肽的制备方法及活性检测	专利	单安山
11	饲料资源开发与利用	专著	单安山\|
12	The influence of isoleucine and arginine on biological activity and peptide-membrane interactions of antimicrobial peptides from the bactericidal domain of AvBD4	期刊论文	Hu WN\|Jiao WJ\|Ma Z\|Dong N\|Ma QQ\|Shao CX\|Shan AS\|
13	Rational design of cationic antimicrobial peptides by the tandem of leucine-rich repeat	期刊论文	QQ Ma\|YF Lv\|Y Gu\|N Dong\|DS Li,\|AS Shan\|
14	Biochemical properties and molecular mechanisms of antibacterial actions of carboxy-terminal RWL-tagged antimicrobial peptides	会议论文	N Dong\|X Zhu\|YF Lv\|QQ Ma\|AS Shan\|
15	The effect of vitamin E on laying performance and egg quality in laying hens fed corn dried distillers grains with solubles	期刊论文	W Jiang\|L Zhang\|A Shan\|
16	Expression in Pichia pastoris and biological activity of avian β-defensin 6 and its mutant peptide without cysteines	期刊论文	CaoYanping\|Ma Qingquan\|Shan Anshan\|Dong Na\|
17	Importance of tryptophan along the nonpolar helix face of an antimicrobial amphipathic peptide for improving killing efficacy against Pseudomonas aeruginosa	会议论文	X Zhu\|AS Shan\|
18	Novel antimicrobial peptides rich in Val/Arg residues and the biological activities in vitro and in vivo	会议论文	QQ Ma\|AS Shan\|
19	Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity and potent antibiofilm activity	期刊论文	X Zhu\|Dong N\|Wang Z\|Ma Z\|Zhang L\|Ma Q\|AS Shan\|
20	Cell selectivity and interaction withmodel membranes of Val/Arg-rich peptides	期刊论文	Qing-QuanMa\|Anshan Shan\|Na Dong\|Yao Gu\|Wen-Yu Sun\|Wan-Ning Hu\|Xing-Jun Feng\|
21	Antitumor effect of the antimicrobial peptide GLI13-8 derived from domain of the avian β-defensin-6	期刊论文	Y Gu\|N Dong\|AS Shan\|QQ Ma\|J Li\|B Cheng\|
22	The Effects of Leu or Val Residues on Cell Selectivity of alpha-Helical Peptides	期刊论文	Ma, Qing-Quan\|Shan, An-Shan\|Dong, Na\|Cao, Yan-Ping\|Lv, Yin-Feng\|Wang, Liang\|

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