高信噪比多色SERS探针的制备及其在癌症精确检测中的应用研究

21775075
2017
B0403.谱学方法与理论
刘定斌
面上项目
研究员
南开大学
65万元
多色成像;表面增强拉曼光谱;光谱分析;金纳米颗粒;临床检测
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Two‐step signal amplification for high‐sensitivity detection of biomarkers using gold nanoparticle–based conjugates 期刊论文 Pengjuan Zhang;Jie Yang;Dingbin Liu
2 Dual-Responsive Self-Assembled Monolayer for Specific Capture and On-Demand Release of Live Cells 期刊论文 Xia Gao;Qiang Li;Fengchao Wang;Xuehui Liu;Dingbin Liu
3 一种双响应型纳米仿生界面的制备及其在细胞捕获与应需无损释放中的应用 专利 刘定斌;高霞
4 General Approach to Engineering Extracellular Vesicles for Biomedical Analysis 期刊论文 Huixia Di;Erzao Zeng;Pengjuan Zhang;Xuehui Liu;Cai Zhang;Jie Yang;Dingbin Liu
5 pH-Mediated Clustering of Exosomes: Breaking Through the Size Limit of Exosome Analysis in Conventional Flow Cytometry 期刊论文 Xinzhuo Liu;Zhiyou Zong;Mindan Xing;Xuehui Liu;Jia Li;Dingbin Liu
6 SERS Tags for Biomedical Detection and Bioimaging 期刊论文 Huiqiao Liu;Xia Gao;Chen Xu;Dingbin Liu
7 Reliable Quantification of pH Variation in Live Cells Using Prussian Blue-Caged Surface-Enhanced Raman Scattering Probes. 期刊论文 Yingna Bi;Huixia Di;Erzao Zeng;Qiang Li;Wenshuai Li;Jie Yang;Dingbin Liu
8 一种基于种子生长法的胶体金病毒抗体检测试剂盒 专利 刘昕倬;刘定斌;庞代文
9 Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging 期刊论文 Bo Dong;Shuangli Du;Chunxiao Wang;Haohao Fu;Qiang Li;Nannan Xiao;Jie Yang;Xue Xue;Wensheng Cai;Dingbin Liu
10 Chemoenzymatic Labeling of Extracellular Vesicles for Visualizing Their Cellular Internalization in Real Time 期刊论文 Ying Jiang;Lei Wang;Pengjuan Zhang;Xuehui Liu;Huixia Di;Jie Yang;Shu-Lin Liu;Dai-Wen Pang;Dingbin Liu
11 Direct cytoplasm delivery of gold nanoparticles for real-time apoptosis detection 期刊论文 Qiang Li;Fengchao Wang;Jie Yang;Dingbin Liu
12 In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation 期刊论文 Pengjuan Zhang;Bo Dong;Erzao Zeng;Fengchao Wang;Ying Jiang;Dianqi Li;Dingbin Liu
13 Nanozyme-assisted sensitive profiling of exosomal proteins for rapid cancer diagnosis. 期刊论文 Huixia Di;Ze Mi;Yan Sun;Xuehui Liu;Xinzhuo Liu;Ang Li;Ying Jiang;Hongmei Gao;Pengfei Rong;Dingbin Liu
14 Stimulus-responsive surface-enhanced Raman scattering: a "Trojan horse" strategy for precision molecular diagnosis of cancer 期刊论文 Cai Zhang;Xiaoyu Cui;Jie Yang;Xueguang Shao;Yuying Zhang;Dingbin Liu
15 Advanced technologies for single-cell in situ protein profiling 期刊论文 Wen Zhou;Xiaoyue Ni;Chen Xie;Quli Fan;Dingbin Liu
16 Alkyne- and Nitrile-Anchored Gold Nanoparticles for Multiplex SERS Imaging of Biomarkers in Cancer Cells and Tissues 期刊论文 Mingmin Li;Jianzhen Wu;Mengtian Ma;Zhichao Feng;Ze Mi;Pengfei Rong;Dingbin Liu
17 Gadolinium-doped Au@prussian blue nanoparticles as MR/SERS bimodal agents for dendritic cell activating and tracking. 期刊论文 Cai Zhang;Zhiwen Xu;Huixia Di;Erzao Zeng;Ying Jiang;Dingbin Liu
18 Assembly of DNA Probes into Superstructures for Dramatically Enhancing Enzymatic Stability and Signal-to-Background Ratio 期刊论文 Fengchao Wang;Qiang Li;Pengjuan Zhang;Xuehui Liu;Ang Li;Jie Yang;Dingbin Liu
19 Multichannel Stimulus-Responsive Nanoprobes for H(2)O(2) Sensing in Diverse Biological Milieus. 期刊论文 Cai Zhang;Xinzhuo Liu;Zhiwen Xu;Dingbin Liu
20 Cross-Linked Poly(ethylene glycol) Shells for Nanoparticles: Enhanced Stealth Effect and Colloidal Stability 期刊论文 Dianqi Li;Fengchao Wang;Huixia Di;Xuehui Liu;Pengjuan Zhang;Wen Zhou;Dingbin Liu
21 Recent advances in background-free Raman scattering for bioanalysis 期刊论文 Xuehui Liu;Xiaoman Liu;Pengfei Rong;Dingbin Liu
22 Release Strategies of Silver Ions from Materials for Bacterial Killing 期刊论文 Zhiwen Xu;Cai Zhang;Xiang Wang;Dingbin Liu
23 Advances in Bacterial Detection Based on Raman Spectroscopy 期刊论文 Wenshuai Li;Guorui Wu;Xijing Zhang;Aiqin Yue;Weijun Du;Jinzhong Zhao;Dingbin Liu
24 Using selenium-conjugated polyethylene glycol to enhance the stability of gold nanoparticles in biologically relevant samples 期刊论文 Yang Xue;Bo Dong;Xuehui Liu;Fengchao Wang;Jie Yang;Dingbin Liu
25 Photoactive Silver Nanoagents for Backgroundless Monitoring and Precision Killing of Multidrug-Resistant Bacteria 期刊论文 Zhiwen Xu;Cai Zhang;Yunjian Yu;Wenshuai Li;Zhuang Ma;Jingjing Wang;Xinge Zhang;Hongmei Gao;Dingbin Liu
26 In-situ monitoring of nitrile-bearing pesticide residues by background-free surface-enhanced Raman spectroscopy 期刊论文 Guorui Wu;Wenshuai Li;Weijun Du;Aiqin Yue;Jinzhong Zhao;Dingbin Liu
27 Click RNA for Rapid Capture and Identification of Intracellular MicroRNA Targets 期刊论文 Pengjuan Zhang;Haohao Fu;Shuangli Du;Fengchao Wang;Jie Yang;Wensheng Cai;Dingbin Liu
28 When Prussian Blue Meets Porous Gold Nanoparticles: A High Signal‐to‐Background Surface‐Enhanced Raman Scattering Probe for Cellular Biomarker Imaging 期刊论文 Xuejing Li;Erzao Zeng;Huixia Di;Qiang Li;Jingwei Ji;Jie Yang;Dingbin Liu
29 Stimuli-Mediated Specific Isolation of Exosomes from Blood Plasma for High-Throughput Profiling of Cancer Biomarkers 期刊论文 Xuehui Liu;Zhiyou Zong;Xinzhuo Liu;Qiang Li;Ang Li;Chen Xu;Dingbin Liu
30 A universal strategy for the one-pot synthesis of SERS tags 期刊论文 Jin Li;Huiqiao Liu;Pengfei Rong;Wen Zhou;Xiaohu Gao;Dingbin Liu
31 Encapsulating a Single Nanoprobe in a Multifunctional Nanogel for High-Fidelity Imaging of Caspase Activity in Vivo 期刊论文 Qiang Li;Xinkai Qiao;Fengchao Wang;Xuejing Li;Jie Yang;Yang Liu;Linqi Shi;Dingbin Liu
32 一种磁/量子点荧光微球新冠病毒抗原抗体定量检测试剂盒 专利 刘安安;刘娟祖;江永忠;胡姣;石学慧;刘定斌;庞代文
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