香菇菌丝体抗氧化多糖通过p38MAPK和JNK通路对糖毒性所致胰岛β细胞损伤保护作用研究

31770017
2017
C0101.微生物多样性、分类与系统发育
曹向宇
面上项目
教授
辽宁大学
55万元
氧化应激;抗氧化;糖毒性;真菌功能活性化合物资源;多糖
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Resveratrol protects human bronchial epithelial cells against nickel-induced toxicity via suppressing p38 MAPK, NF-kappa B signaling, and NLRP3 inflammasome activation 期刊论文 Cao Xiangyu;Tian Siqi;Fu Mingyang;Li Yanmei;Sun Yueling;Liu Jianli;Liu Yue
2 Spectroscopy and molecular docking analysis reveal structural specificity of flavonoids in the inhibition of alpha-glucosidase activity 期刊论文 Liu Jian-li;Kong Yu-chi;Miao Jing-yi;Mei Xue-ying;Wu Shu-yao;Yan Yi-chen;Cao Xiang-yu
3 Alantolactone induces apoptosis and suppresses migration in MCF-7 human breast cancer cells via the p38 MAPK, NF-kappa B and Nrf2 signaling pathways 期刊论文 Liu Jianli;Liu Meijia;Wang Shuai;He Yin;Huo Yapeng;Yang Zhijun;Cao Xiangyu
4 Ferulic acid inhibits advanced glycation end products (AGEs) formation and mitigates the AGEs-induced inflammatory response in HUVEC cells 期刊论文 Liu Jian-li;He Yong-lin;Wang Shuai;He Yin;Wang Wei-yu;Li Qi-jiu;Cao Xiang-yu
5 Elucidating the interaction mechanism of eriocitrin with beta-casein by multi-spectroscopic and molecular simulation methods 期刊论文 Cao Xiangyu;He Yonglin;Kong Yuchi;Mei Xueying;Huo Yapeng;He Yin;Liu Jianli
6 Characterization of interaction between scoparone and bovine serum albumin: spectroscopic and molecular docking methods 期刊论文 Cao Xiangyu;He Yonglin;Liu Dan;He Yin;Hou Xiao;Cheng Ye;Liu Jianli
7 A study on the protective effects of taxifolin on human umbilical vein endothelial cells and THP-1 cells damaged by hexavalent chromium: a probable mechanism for preventing cardiovascular disease induced by heavy metals 期刊论文 Xiangyu Cao;Ruochen Bi;Jianli Hao;Shuai Wang;Rahewa Mahir Demoz;Ruth Banda;Siqi Tian;Chong Xin;Mingyang Fu;Jingwen Pi;Jianli Liu
8 Bovine lactoferrin and Lentinus edodes mycelia polysaccharide complex: The formation and the activity to protect islet β cells 期刊论文 Xiangyu Cao;Chengying Liu;Mengmeng Zhang;Ruochen Bi;Mingyang Fu;Elena Korik;Jiahe Chen;Jianyun Gao;Igor Semak;Jianli Liu
9 Toxic effects of Cr(VI) on the bovine hemoglobin and human vascular endothelial cells: Molecular interaction and cell damage 期刊论文 Cao Xiangyu;Wang Shuai;Bi Ruochen;Tian Siqi;Huo Yapeng;Liu Jianli
10 香菇菌丝体多糖在制备抑制淀粉酶活性药物中的应用 专利 曹向宇;夏莹;程野;谢言真;唐志鹏;梅雪迎;丁尉哲
11 香菇多糖在制备抑制α-葡萄糖苷酶活性药物中的应用 专利 曹向宇;孔宇驰;繆静宜;何勇林;李其久;牟藤
12 Eriodictyol and naringenin inhibit the formation of AGEs: An in vitro and molecular interaction study 期刊论文 Liu Jianli;Yang Zhijun;Cheng Ye;Wu Qiong;He Yin;Li Qijiu;Cao Xiangyu
13 Nobiletin inhibits breast cancer via p38 mitogen-activated protein kinase, nuclear transcription factor-κB, and nuclear factor erythroid 2-related factor 2 pathways in MCF-7 cells 期刊论文 Jianli Liu;Shuai Wang;Siqi Tian;Yin He;Hong Lou;Zhijun Yang;Yuchi Kong;Xiangyu Cao
14 Antitumor activity of alantolactone in lung cancer cell lines NCI-H1299 and Anip973 期刊论文 Liu Jianli;Yang Zhijun;Kong Yuchi;He Yin;Xu Yongliang;Cao Xiangyu
15 香菇多糖在制备预防糖尿病并发症药物中 的应用 专利 曹向宇;孔宇驰;何勇林;贺音;蔡天革;唐志鹏;李其久
16 Inhibitory mechanismof sinensetin onα-glucosidase and non-enzymatic glycation: Insights from spectroscopy and molecular docking analyses 期刊论文 Dan Liu;Xiangyu Cao;Yuchi Kong;Teng Mu;Jianli Liu
17 Analysis of the binding mechanism between o-phenylenediamine and bovine hemoglobin by molecular spectroscopy and molecular modeling methods 期刊论文 Liu Jian-Li;Kong Yu-Chi;Miao Jing-Yi;He Yong-Lin;Bi Ruo-Chen;He Yin;Cao Xiang-Yu
18 A novel polysaccharide from Lentinus edodes mycelia protects MIN6 cells against high glucose-induced damage via the MAPKs and Nrf2 pathways 期刊论文 Cao Xiangyu;Liu Dan;Xia Ying;Cai Tiange;He Yin;Liu Jianli
19 Multispectroscopic exploration and molecular docking analysis on interaction of eriocitrin with bovine serum albumin 期刊论文 Cao Xiangyu;Yang Zhijun;He Yonglin;Xia Ying;He Yin;Liu Jianli
20 Caffeic Acid Inhibits the Formation of Advanced Glycation End Products (AGEs) and Mitigates the AGEs-Induced Oxidative Stress and Inflammation Reaction in Human Umbilical Vein Endothelial Cells (HUVECs) 期刊论文 Cao Xiangyu;Xia Ying;Zeng Meng;Wang Weiyu;He Yin;Liu Jianli
21 The protective effects of a novel polysaccharide from Lentinus edodes mycelia on islet beta (INS-1) cells damaged by glucose and its transportation mechanism with human serum albumin 期刊论文 Cao Xiang-yu;Liu Dan;Bi Ruo-chen;He Yong-lin;He Yin;Liu Jian-li
22 Inhibitory effects of Lentinus edodes mycelia polysaccharide on alpha-glucosidase, glycation activity and high glucose-induced cell damage 期刊论文 Cao Xiangyu;Xia Ying;Liu Dan;He Yonglin;Mu Teng;Huo Yapeng;Liu Jianli
23 Characterizing the binding interaction of astilbin with bovine serum albumin: a spectroscopic study in combination with molecular docking technology 期刊论文 Liu Jianli;He Yonglin;Liu Dan;He Yin;Tang Zhipeng;Lou Hong;Huo Yapeng;Cao Xiangyu
24 Spectroscopic and molecular modeling studies on the interactions of fluoranthene with bovine hemoglobin 期刊论文 Cao Xiang-yu;Wang Shuai;Tian Si-qi;Lou Hong;Kong Yu-chi;Yang Zhi-jun;Liu Jian-li
25 Protective Effects of Anthocyanins from Coreopsis tinctoria against Oxidative Stress Induced by Hydrogen Peroxide in MIN6 Cells 期刊论文 Liu Jianli;Tian Siqi;Fu Mingyang;He Yin;Yu Hui;Cao Xiangyu;Cao Yiyang;Xu Hanyuan
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