BDNF调节记忆形成和消退的神经环路机制研究

31130026
2011
C0906.认知神经生物学
陈哲宇
重点项目
教授
山东大学
312万元
BDNF;记忆形成;TrkB受体;记忆消退;条件性味觉厌恶学习
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Myosin Va mediates BDNF-induced postendocytic recycling of full-length TrkB and its translocation into dendritic spines 期刊论文 Wang, Jue|Chen, Qun|Liu, Ting|Chen, Zhe-Yu|
2 Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling 期刊论文 Rafii, Shahin|Chen, Zhe-Yu|Rodriguez-Boulan, Enrique|Lee, Francis S.|
3 Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion 期刊论文 S. H. Huang|L. Zhao|J. Wang|Z. Y. Chen|
4 c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) regulates neuronal axon elongation in a kinesin- and JNK-dependent manner. 期刊论文 Huang, Zhuo|Jiang, Xing-Yu|Shen, Ying|Chen, Zhe-Yu|
5 BDNF-dependent recycling facilitates TrkB translocation to postsynaptic density during LTP via a Rab11-dependent pathway. 期刊论文 Zhang, Xiao-Yan|Yan, Jing|Geng, Zhao|Chen, Zhe-Yu|
6 Integrin-linked Kinase is Essential for Environmental Enrichment Enhanced Hippocampal Neurogenesis and Memory 期刊论文 Wang, Dong-Dong|Chen, Bing|Wang, Yue|Chen, Zhe-Yu|
7 Involvement of BDNF Signaling Transmission from Basolateral Amygdala to Infralimbic Prefrontal Cortex in Conditioned Taste Aversion Extinction 期刊论文 Yu, Hui|Wang, Yue|Kong, Liang|Chen, Zhe-Yu|
8 Syntaxin 8 modulates the post-synthetic trafficking of the TrkA receptor and inflammatory pain transmission. 期刊论文 Ji, Yun-Song|Li, Na|Xu, Xu-Feng|Chen, Zhe-Yu|
9 LIM Kinase 1 (LIMK1) Interacts with Tropomyosin-related Kinase B (TrkB) and Mediates Brain-derived Neurotrophic Factor (BDNF)-induced Axonal Elongation 期刊论文 Q. Dong|Y. S. Ji|C. Cai|Z. Y. Chen|
10 Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission. 期刊论文 Ji, Yun-Song|Sun, Xu-lu|Liu, Xiang-Hua|Chen, Zhe-Yu|
11 Differential involvement of brain-derived neurotrophic factor in reconsolidation and consolidation of conditioned taste aversion memory 期刊论文 T. Li|H. Yu|N. Li|Z. Y. Chen|
12 Myosin II regulates actin rearrangement-related structural synaptic plasticity during conditioned taste aversion memory extinction 期刊论文 Li, Bo-Qin|Sun, Zong-Peng|Bi, Hong-Sheng|Chen, Zhe-Yu|
13 Blockage of GSK3 beta-mediated Drp1 phosphorylation provides neuroprotection in neuronal and mouse models of Alzheimer's disease 期刊论文 Yu, Nuo|Li, Ting|Su, Bo|Chen, Zhe-Yu|
14 Hippocampal Wnt3a is Necessary and Sufficient for Contextual Fear Memory Acquisition and Consolidation. 期刊论文 Wang, Yue|Huang, Shu-Hong|Li, Xian|Chen, Zhe-Yu|
15 Up-regulationof c-Jun NH2-terminal kinase-interacting protein 3 (JIP3) contributes toBDNF-enhanced neurotransmitter release 期刊论文 Huang, Shu-Hong|Zhai, Lu-Kai|Guo, Yun-Yun|Chen, Zhe-Yu|
16 Blocking GSK3 beta-mediated dynamin1 phosphorylation enhances BDNF-dependent TrkB endocytosis and the protective effects of BDNF in neuronal and mouse models of Alzheimer's disease 期刊论文 Li, Ting|Chen, Qun|Zhang, Qun-Ye|Chen, Zhe-Yu|
17 Transcriptome Profiling Analysis of the Mechanisms Underlying the BDNF Val66Met Polymorphism Induced Dysfunctions of the Central Nervous System 期刊论文 Xu, Xu-Feng|Yu, Hui|Wang, Yue|Chen, Zhe-Yu|
18 Phosphorylation of cofilin regulates extinction of conditioned aversive memory via AMPAR trafficking. 期刊论文 Wang, Dong-Dong|Yu, Hui|Tian, Tian|Chen, Zhe-Yu|
19 Retinoic acid ameliorates blood-brain barrier disruption following ischemic stroke in rats 期刊论文 Wang, Xiao-Tong|Zhao, Yan|Wang, Li-Mei|Chen, Zhe-Yu|
20 Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants 期刊论文 Y. Wang|T. Liu|F. S. Lee|Z. Y. Chen|
21 BDNF-dependent recycling facilitates TrkB translocation to postsynaptic density during LTP via a Rab11-dependent pathway. 期刊论文 Zhang, Xiao-Yan|Yan, Jing|Geng, Zhao|Chen, Zhe-Yu|
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