猪瘟病毒感染诱导的内质网应激-自噬对其免疫逃逸的调控作用及机制研究
U1405216
2014
C1802.兽医病毒学
陈金顶
联合基金项目
教授
华南农业大学
272万元
分子机制;猪瘟病毒;内质网应激;细胞自噬;免疫逃逸
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Avian Interferon-Inducible Transmembrane Protein Family Effectively Restricts Avian Tembusu Virus Infection | 期刊论文 | Chen Shilong;Wang Long;Chen Jieying;Wang Song;Goraya Mohsan U.;Chi Xiaojuan;Na Yang;Shao Wenhan;Yang Zhou;Zeng Xiancheng;Chen Ji-Long;Chen Shilong;Chen Shilong;Chen Shaoying;Chen Ji-Long;Chen JL;Chen JL |
| 2 | Role of innate immunity in pathophysiology of classical swine fever virus infection | 期刊论文 | Goraya Mohsan Ullah;Chen Ye;Chi Xiaojuan;Goraya Mohsan Ullah;Ziaghum Fozia;Chen Shilong;Raza Ali;Goraya MU |
| 3 | CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis | 期刊论文 | Gou Hongchao;Zhao Mingqiu;Xu Hailuan;Yuan Jin;He Wencheng;Zhu Mengjiao;Ding Hongxing;Yi Lin;Chen Jinding;Chen JD |
| 4 | CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication | 期刊论文 | He Wencheng;Xu Hailuan;Gou Hongchao;Yuan Jin;Liao Jiedan;Chen Yuming;Fan Shuangqi;Xie Baoming;Deng Shaofeng;Zhang Yangyi;Chen Jinding;Zhao Mingqiu;Chen JD;Zhao MQ |
| 5 | 一种检测猪瘟病毒的重组酶常温扩增核酸(RT-RPA)试纸条试剂盒及应用 | 专利 | 陈金顶;张静远;范双旗;徐海娈;刘志香;赵明秋;李军 |
| 6 | Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling | 期刊论文 | Zeng Xiancheng;Wang Song;Chi Xiaojuan;Chen Shi-long;Lin Qunqun;Chen Ji-Long;Zeng Xiancheng;Xie Baogui;Huang Shile;Chen Ji-Long;Chen JL;Xie BG;Chen JL |
| 7 | Induction of innate immunity and its perturbation by influenza viruses | 期刊论文 | Goraya Mohsan Ullah;Wang Song;Chen Ji-Long;Munir Muhammad;Chen Ji-Long;Chen JL |
| 8 | Robust expression of vault RNAs induced by influenza A virus plays a critical role in suppression of PKR-mediated innate immunity | 期刊论文 | Li Fang;Chen Yuhai;Zhang Zhaoyuan;Ouyang Jing;Wang Yi;Gao George Fu;Guo Guijie;Chen Ji-Long;Zhang Zhaoyuan;Yan Ruoxiang;Chen Ji-Long;Huang Shile;Chen JL |
| 9 | Activation of Interleukin-1 beta Release by the Classical Swine Fever Virus Is Dependent on the NLRP3 Inflammasome, Which Affects Virus Growth in Monocytes | 期刊论文 | Fan Shuangqi;Yuan Jin;Deng Shaofeng;Chen Yuming;Xie Baoming;Wu Keke;Zhu Mengjiao;Xu Hailuan;Huang Yunzhen;Yang Jiongfeng;Zhang Yangyi;Chen Jinding;Zhao Mingqiu;Chen JD;Zhao MQ |
| 10 | Atypical Porcine Pestivirus as a Novel Type of Pestivirus in Pigs in China | 期刊论文 | Yuan Jin;Han Zhiyong;Li Jun;Huang Yunzhen;Yang Jiongfeng;Ding Hongxing;Zhang Jingyuan;Zhu Mengjiao;Zhang Yangyi;Liao Jiedan;Zhao Mingqiu;Chen Jinding;Zhao MQ;Chen JD |
| 11 | Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV | 期刊论文 | Gou Hongchao;Zhao Mingqiu;Fan Shuangqi;Yuan Jin;Liao Jiedan;He Wencheng;Xu Hailuan;Chen Jinding;Chen JD |
| 12 | 猪瘟病毒RT-LAMP-LFD检测方法的建立与应用 | 期刊论文 | 朱俊灵;叶佐东;邓洁汝;勾红潮;陈金顶 |
| 13 | 检测非典型猪的瘟病毒的绝对荧光定量PCR引物及试剂盒 | 专利 | 陈金顶;朱梦娇;邓少锋;范双旗;张静远;李军;丁红星 |
| 14 | 广东西藏小型猪血液生理生化指标的分析 | 期刊论文 | 廖洁丹;林连蓬;梁楚瑶;杨权;罗怡;苏幸尧;赵明秋;陈金顶 |
| 15 | 西藏小型猪对猪瘟病毒的敏感性评价 | 期刊论文 | 廖洁丹;黄允真;范双旗;丁红星;赵明秋;陈金顶 |
| 16 | Targeted disruption of influenza A virus hemagglutinin in genetically modified mice reduces viral replication and improves disease outcome | 期刊论文 | Wang Song;Chen Chao;Yang Zhou;Chi Xiaojuan;Chen Ji-Long;Zhang Jing;Chen Ji-Long;Chen JL;Chen JL |
| 17 | Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells | 期刊论文 | Pei Jingjing;Deng Jieru;Ye Zuodong;Wang Jiaying;Gou Hongchao;Liu Wenjun;Zhao Mingqiu;Liao Ming;Yi Lin;Chen Jinding |
| 18 | Rapid and sensitive detection of porcine epidemic diarrhea virus by reverse transcription loop-mediated isothermal amplification combined with a vertical flow visualization strip | 期刊论文 | Hongchao Gou;Jieru Deng;Jiaying Wang;Jingjing Pei;Wenjun Liu;Mingqiu Zhao;Jinding Chen |
| 19 | Metabolic Profiles in cell Lines Infeted with Classical Swine Fever Virus | 期刊论文 | Gou Hongchao;Zhao Mingqiu;Yuan Jin;Xu Hailuan;Ding Hongxing;Chen Jinding;Chen JD |
| 20 | 猪瘟病毒与宿主天然免疫系统的相互作用 | 期刊论文 | 蔡彬祥;於子鼎;曾显成;池晓娟;陈吉龙 |
| 21 | PK-15 细胞中与 CSFV 感染相关的 microRNAs 筛选及miR-214 的功能研究 | 期刊论文 | 邓少锋;叶佐东;范双旗;陈金顶;张静远;朱梦娇;赵明秋 |
| 22 | Infection with classical swine fever virus induces expression of type III interferons and activates innate immune signaling | 期刊论文 | Binxiang Cai;Qingling Bai;Xiaojuan Chi;Mohsan Ullah Goraya;Long Wang;Song Wang;Biao Chen;Ji-Long Chen |
| 23 | Comprehensive analysis of the codon usage patterns in the envelope glycoprotein E2 gene of the classical swine fever virus | 期刊论文 | Chen Ye;Li Xinxin;Chi Xiaojuan;Wang Song;Ma Yanmei;Chen Jilong;Chen Jilong;Ma YM;Chen JL;Chen JL |
| 24 | Muscovy duck reovirus infection rapidly activates host innate immune signaling and induces an effective antiviral immune response involving critical interferons | 期刊论文 | Chen Zhilong;Luo Guifeng;Wang Quanxi;Wang Song;Chi Xiaojuan;Huang Yifan;Wu Baocheng;Chen Ji-Long;Wei Haitao;Chen Ji-Long;Huang Shile;Wang QX |
| 25 | Classical swine fever virus induces pyroptosis in the peripheral lymphoid organs of infected pigs | 期刊论文 | Yuan Jin;Zhu Mengjiao;Deng Shaofeng;Fan Shuangqi;Xu Hailuan;Liao Jiedan;Li Peng;Zheng Jingfang;Zhao Mingqiu;Chen Jinding;Zhao MQ;Chen JD |
| 26 | PKR activation enhances replication of classical swine fever virus in PK-15 cells | 期刊论文 | Liu Wen-Jun;Yang You-Tian;Zhao Ming-Qiu;Dong Xiao-Ying;Gou Hong-Chao;Pei Jing-Jing;Chen Jin-Ding;Chen JD |
| 27 | Avian Tembusu virus infection effectively triggers host innate immune response through MDA5 and TLR3-dependent signaling pathways | 期刊论文 | Chen Shilong;Luo Guifeng;Yang Zhou;Lin Shuncheng;Wang Song;Goraya Mohsan Ullah;Chi Xiaojuan;Zeng Xiancheng;Chen Ji-Long;Chen Shilong;Chen Ji-Long;Chen Shilong;Chen Shaoying;Chen JL |
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