确认细胞能量感受器为新结构类型化合物调血脂作用靶标的体内外研究

30973527
2009
H3502.心脑血管药物药理
朱海波
面上项目
研究员
中国医学科学院
30万元
靶标;调血脂作用;新结构类型化合物WS070117;细胞能量感受器
2010-01-01到2012-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Beneficial Metabolic Effects of 2',3',5'-tri-acetyl-N-6-(3-Hydroxylaniline) Adenosine in the Liver and Plasma of Hyperlipidemic Hamsters 期刊论文 Sun, Yang|Lian, Zeqin|Jiang, Chunying|Wang, Yinghong|Zhu, Haibo|
2 Effects of Gossypium herbaceam Extract Administration on the Learning and Memory Function in the Naturally Aged Rats: Neuronal Niche Improvement. 期刊论文 Yanyong Liu|Haji Akber Aisa|Chao Ji|Nan Yang|Haibo Zhu|Pingping Zuo|
3 A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells 期刊论文 Zeqin Lian|Yan Li|Jian Gao|Kai Qu|Jin Li|Linghua Hao|Song Wu|Haibo Zhu|
4 蛹虫草提取物虫草素(3';-脱氧腺苷)对于高脂血症地鼠和大鼠的降血脂作用研究(英文) 期刊论文 高健|连泽勤|朱平|朱海波|
5 A simple and sensitive method for lipoprotein and lipids profiles analysis of individual micro-liter scale serum samples 期刊论文 Yang, Liu|Fan, Baoyan|Yang, Kangmin|Zhu, Haibo|
6 The adenosine derivative 2′ ,3 ′ ,5 ′ -tri-O-acetyl-N6-(3-hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo. 期刊论文 Peng Guo|Ze-qin Lian|Ling-hui Sheng|Chong-ming Wu|Jian Gao|Jin Li|Yao Wang|Haibo Zhu|
7 Cordycepin Prevents Hyperlipidemia in Hamsters Fed a High-Fat Diet via Activation of AMP-Activated Protein Kinase 期刊论文 Guo, Peng|Kai, Qu|Gao, Jian|Lian, Ze-qin|Wu, Chong-ming|Wu, Cheng-ai|Zhu, Hai-bo|
8 In vitro stability and metabolism of O2', O3', O5'-tri-acetyl-N6-(3-hydroxylaniline) adenosine in rat, dog and human plasma: chemical hydrolysis and role of plasma esterases 期刊论文 Liu Y|He J|Abliz Z|Zhu H|
9 Novel LDL-oriented pharmacotherapeutical strategies 期刊论文 Huang, Lin-Zhang|Zhu, Hai-Bo|
10 Binding of Cordycepin Monophosphate to AMP-Activated Protein Kinase and its Effect on AMP-Activated Protein Kinase Activation 期刊论文 Wang, Zhanli|Wang, Xing|Qu, Kai|Zhu, Ping|Guo, Na|Zhang, Ruiping|Abliz, Zeper|Yu, Hui|Zhu, Haibo|
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