具有多重抗肿瘤耐药机制的微管稳定剂小分子的结构优化与类药性评价
序号 | 标题 | 类型 | 作者 |
---|---|---|---|
1 | Free Energy Profile and Kinetics Studies of Paclitaxel Internalization from the Outer to the Inner Wall of Microtubules | 期刊论文 | Maccari, Giorgio|Mori, Mattia|Rodriguez-Salarichs, Javier|Fang, Weishuo|Fernando Diaz, Jose|Botta, Maurizio| |
2 | A semisynthetic taxane yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro | 会议论文 | Cai Pei|Peihua Lu|Frances J. Sharom|Weishuo Fang| |
3 | A new and efficient synthesis of cabazitaxel. Journal of Chinese Pharmaceutical Sciences 2012, 21(5): 472-476. | 期刊论文 | Guo-Ning zhang|Wei-Shuo Fang| |
4 | Synthesis and Biological Evaluation of Colchicine B-Ring Analogues Tethered with Halogenated Benzyl Moieties | 期刊论文 | Pors, Klaus|Redondo-Horcajo, Mariano|Zhao, Ying|Santos, Ana Rita|Chowdury, Kaniz F.|Vinader, Victoria|Abdallah, Qasem M. A.|Abdel-Rahman, Hamdy|Fournier-Dit-Chabert, Jeremie| |
5 | 具有抗多药耐药肿瘤细胞系活性的紫杉醇衍生物的设计、合成和抗肿瘤活性研究 | 会议论文 | 汤湧|方唯硕| |
6 | Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport | 期刊论文 | Fang, W. S.|Wu, J.|Trigili, C.|Chen, H.|Chu, J. W. K.|Zhao, Y.|Lu, P. H.|Sheng, L.|Li, Y.| |
7 | Modulation of microtubule interprotofilament interactions by modified taxanes | 期刊论文 | José Fernando Díaz|Javier Rodríguez-Salarichs|Benet Pera|Ángeles Canales|José Manuel Andreu|Jesús Jiménez-Barbero|Wim Bras|Aurora Nogales|Wei-Shuo Fang| |
8 | A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and beta-III tubulin mediated tumor drug resistance in vitro | 期刊论文 | Cai, P.|Lu, P. H.|Sharom, F. J.|Fang, W. S.| |
9 | Synthesis of B-seco paclitaxel derivatives | 会议论文 | Yu Zhao|Pei Cai|Ruth Matesanz|Gonzalo Sáez|Fernando Díaz|Weishuo Fang| |
10 | Novel 4-Methyl-4-Deacetyl D-Seco Paclitaxel Analogues | 会议论文 | Shaorong Wang|Chungang Yang|Ruth Matesanz|Ana Angelica Alcaraz|James P. Snyder|Weishuo Fang| |