Ⅰ型干扰素抗炎症作用影响肺脏和肠道区域性免疫的分子机制研究
91542201
2015
C0803.黏膜免疫与区域免疫
程根宏
重大研究计划
教授
中国医学科学院
235万元
肺脏和肠道区域性免疫;分子机制;细胞因子IFN-I-IL27-IL10联合效应程序;流感感染继发细菌性肺炎;Ⅰ型干扰素抗炎症作用
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | E90 Subunit Vaccine Protects Mice From Zika Virus Infection and Microcephaly | 期刊论文 | Xingliang Zhu;Chunfeng Li;Shabbir Khan Afridi;Shulong Zu;Genhong Cheng;Zhiheng Xu |
| 2 | 一种流感病毒株及其应用 | 专利 | 程根宏 |
| 3 | Generation of a Live Attenuated Influenza Vaccine That Elicits Broad Protection in Mice and Ferrets | 期刊论文 | Lulan Wang;Su-Yang Liu;Hsiang-Wen Chen;Juan Xu;Maxime Chapon;Tao Zhang;Fan Zhou;Yao E Wang;Natalie Quanquin;Guiqin Wang;Xiaolin Tian;Zhanllong He;Longding Liu;Wenhai Yu;David Jesse Sanchez;Yuying Liang;Taijiao Jiang;Robert Modlin;Barry R Bloom;Qihan Li;Jane C Deng;Paul Zhou;F Xiao-feng Qin;Genhong Cheng |
| 4 | PARP12 Suppresses Zika Virus Infection Through PARP-dependent Degradation of NS1 and NS3 Viral Proteins | 期刊论文 | Lili Li;Hui Zhao;Ping Liu;Chunfeng Li;Natalie Quanquin;Xue Ji;Nina Sun;Peishuang Du;Cheng-feng Qin;Ning Lu;Genhong Cheng |
| 5 | Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and Its Associated Congenital Microcephaly in Mice | 期刊论文 | Chunfeng Li;Xingliang Zhu;Xue Ji;Natalie Quanquin;Yong-Qiang Deng;Min Tian;Roghigy Aliyari;Xiangyang Zuo;Ling Yuan;Shabbir Khan Afridi;Xiao-feng Li;Jae U Jung;Karin Nielsen-Saines;Frank Xiao-feng Qin;Chengfeng Qin;Zhiheng Xu;Genhong Cheng |
| 6 | Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx | 期刊论文 | Guangyun Tan;Fengchao Xu;Hongxiao Song;Ye Yuan;Qingfei Xiao;Feng Ma;F Xiao-Feng Qin;Genhong Cheng |
| 7 | 25-Hydroxycholesterol Protects Host Against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model | 期刊论文 | Chunfeng Li;Yong-Qiang Deng;Shuo Wang;Feng Ma;Roghiyh Aliyari;Xingyao Huang;Bennett G. Novitch;Zhiheng Xu;Chengfeng Qin;Genhong Cheng |
| 8 | 一种流感病毒弱毒活疫苗毒株的筛选和鉴定方法 | 专利 | 程根宏 |
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