筑波链霉菌产他克莫司的代谢调控机制解析及定向改造

31800072
2018
C0104.微生物遗传与生物合成
刘欢欢
青年科学基金项目
讲师
天津科技大学
25万元
链霉菌;系统生物学;代谢工程育种;代谢网络;他克莫司
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Omics-based analyses revealed metabolic responses of Clostridium acetobutylicum to lignocellulose-derived inhibitors furfural, formic acid and phenol stress for butanol fermentation 期刊论文 Liu Huanhuan;Zhang Jing;Yuan Jian;Jiang Xiaolong;Jiang Lingyan;Zhao Guang;Huang Di;Liu Bin
2 一株筑波链霉菌诱变株及其在联产他克莫司与双烯他克莫司中的应用 专利 刘欢欢;舒林;李贞景;郭庆彬;许慧敏;成颖;李居行;赵娇娇
3 一种白黄链霉菌及利用该微生物制备生防微生物菌剂的方法与应用 专利 王昌禄;薛意斌;路来风;李贞景;刘春静;武淑芬;陈勉华;郭庆彬;刘欢欢;杨明冠;李风娟
4 Gene coexpression network analysis reveals a novel metabolic mechanism ofClostridium acetobutylicumresponding to phenolic inhibitors from lignocellulosic hydrolysates 期刊论文 Liu Huanhuan;Zhang Jing;Yuan Jian;Jiang Xiaolong;Jiang Lingyan;Li Zhenjing;Yin Zhiqiu;Du Yuhui;Zhao Guang;Liu Bin;Huang Di
5 Comparative metabolomics analysis reveals the metabolic regulation mechanism of yellow pigment overproduction by Monascus using ammonium chloride as a nitrogen source. 期刊论文 Liu Huanhuan;Zhang Jing;Lu Gege;Wang Fanghui;Shu Lin;Xu Huimin;Li Zhenjing;Wang Yurong;Guo Qingbin;Wu Shufen;Jiang Lingyan;Wang Changlu;Huang Di;Liu Bin
6 Construction and optimization of a microbial platform for sustainable biosynthesis of poly-N-acetyllactosamine glycoprotein in the cytoplasm for detecting tumor biomarker galectin-3 期刊论文 Yuan Jian;Jiang Xiaolong;Zhang Huijing;Bai Jing;Zhang Jing;Wang Yuhui;Lu Gege;Xu Huimin;Liu Huanhuan;Liu Bin;Huang Di
7 Integrative Metabolomic and Transcriptomic Analyses Uncover Metabolic Alterations and Pigment Diversity in Monascus in Response to Different Nitrogen Sources. 期刊论文 Huang Di;Wang Yuhui;Zhang Jing;Xu Huimin;Bai Jing;Zhang Huijing;Jiang Xiaolong;Yuan Jian;Lu Gege;Jiang Lingyan;Liao Xiaoping;Liu Bin;Liu Huanhuan
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