新型可激活超分子光敏剂的设计制备与构效关系

21473033
2014
B0505.复合与杂化材料化学
黄剑东
面上项目
研究员
福州大学
83万元
硅酞菁;层状复合金属氢氧化物;光敏剂;超分子;光动力治疗
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A tumor-targeted activatable phthalocyanine- tetrapeptide-doxorubicin conjugate for synergistic chemo-photodynamic therapy 期刊论文 Mei-Rong Ke;Shao-Fang Chen;Xiao-Hui Peng;Qiao-Feng Zheng;Bi-Yuan Zheng;Chih-Kuang Yeh;Jian-Dong Huang
2 Synthesis and biological characterization of novel rose bengal derivatives with improved amphiphilicity for sono-photodynamic therapy 期刊论文 Chen Hai-Jun;Zhou Xiao-Bin;Wang Ai-Lan;Zheng Bi-Yuan;Yeh Chih-Kuang;Huang Jian-Dong
3 一种轴向取代酞菁硅配合物及其阿霉素偶联物 专利 黄剑东;柯美荣;陈少芳
4 Highly photocytotoxic silicon(Ⅳ) phthalocyanines axially modified with L-tyrosine derivatives: Effects of mode of axial substituent connection and of formulation on photodynamic activity 期刊论文 Qun Sun;Bi-Yuan Zheng;Yan-Hong Zhang;Jing-Jing Zhuang;Mei-Rong Ke;Jian-Dong Huang
5 磺化酞菁与白蛋白复合物的制备与性质研究 会议论文 张丽娟;李兴淑;李洪才;郑碧远;黄剑东
6 A Tumor-pH-Responsive supramolecular photosensitizer for activatable photodynamic therapy that has minimal in Vivo skin phototoxicity 期刊论文 Xingshu Li;Bi-Yuan Zheng;Mei-Rong Ke;Yongfan Zhang;Jian-Dong Huang;Juyoung Yoon
7 Comparison between amine-terminated phthalocyanines and their chlorambucil conjugates: synthesis, spectroscopic properties, and in vitro anticancer activity 期刊论文 Xiao-Hui Peng;Shao-Fang Chen;Bi-Yuan Zheng;Bing-De Zheng;Qiao-Feng Zheng;Xing-Shu Li;Mei-Rong Ke;Jian-Dong Huang
8 The effects of formulation and serum albumin on the in vitro photodynamic activity of zinc(II) phthalocyanines substituted with sulfonated quinolineoxy groups 期刊论文 Wen-Liang Lan;Feng-Ran Liu;Mei-Rong Ke;Pui-Chi Lo;Wing-Ping Fong;Dennis K.P. Ng;Jian-Dong Huang
9 New application of phthalocyanine molecules: from photodynamic therapy to photothermal therapy by means of structural regulation rather than formation of aggregates 期刊论文 Li Xingshu;Peng Xiao-Hui;Zheng Bing-De;Tang Jilin;Zhao Yuanyuan;Zheng Bi-Yuan;Ke Mei-Rong;Huang Jian-Dong
10 A pH-Responsive Layered Double Hydroxide (LDH)-Phthalocyanine Nanohybrid for Efficient Photodynamic Therapy 期刊论文 Li Xing-Shu; Ke Mei-Rong; Huang Wei; Ye Chun-Hong; Huang Jian-Dong
11 酞菁-水滑石复合物的制备与光动力抗癌活性 会议论文 黄剑东;李兴淑;张艳红;孙群;李东;郑碧远;柯美荣
12 C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy 期刊论文 Wan Dong-Hua;Zheng Bi-Yuan;Ke Mei-Rong;Duan Ji-Ying;Zheng Yun-Quan;Yeh Chih-Kuang;Huang Jian-Dong
13 Synthesis, Spectroscopic and Fibroblast Activation Protein (FAP)-Responsive Properties of Phthalocyanine-Doxorubicin Conjugates 期刊论文 Peng Xiao-Hui;Chen Shao-Fang;Xu Cai-Hong;Zheng Bi-Yuan;Ke Mei-Rong;Huang Jian-Dong
14 一种周边单取代的酞菁锌配合物及其阿霉素偶联物 专利 黄剑东;陈少芳;郑碧远
15 一种轴向酯键连接派啶或吗啉衍生物的硅酞菁 专利 黄剑东;蔡亦斌;柯美荣;郑碧远
16 一种轴向ALA修饰的硅酞菁及其制备方法和应用 专利 黄剑东;庄静静;郑碧远;柯美荣;黄薇
17 新型酞菁衍生物的光物理光化学性质和离体抗真菌活性 会议论文 郑碧远;柯美荣;赵阳;黄剑东
18 Progress in the development of nanosensitizers for X-ray-induced photodynamic therapy 期刊论文 Ren Xu-Dong;Hao Xiu-Yun;Li Hong-Cai;Ke Mei-Rong;Zheng Bi-Yuan;Huang Jian-Dong
19 Phthalocyanine-Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in Photodynamic Therapy 期刊论文 Li Xingshu;Lee Dayoung;Huang Jian-Dong;Yoon Juyoung
20 Preparation and antifungal properties of monosubstituted zinc(П) phthalocyanine-chitosan oligosaccharide conjugates and their quaternized derivatives 期刊论文 Feng-Xiang Tang;Hong-Cai Li;Xu-Dong Ren;Ya Sun;Wei Xie;Cheng-Yu Wang;Bi-Yuan Zheng;Mei-Rong Ke;Jian-Dong Huang
21 可激活抗癌光敏剂 期刊论文 郑秉得;赵园园;李洪才;郑碧远;柯美荣;黄剑东
22 新型十二阳离子酞菁锌(Ⅱ)的合成及光动力抗菌活性研究 会议论文 赵阳;李洪才;李兴淑;郑碧远;柯美荣;黄剑东
23 Synthesis and photodynamic activities of integrin-targeting silicon(IV) phthalocyanine-cRGD conjugates 期刊论文 Zheng Bi-Yuan;Yang Xiao-Qing;Zhao Yang;Zheng Qiao-Feng;Ke Mei-Rong;Lin Tao;Chen Ren-Xun;Ho Kitty K. K.;Kumar Naresh;Huang Jian-Dong
24 Phthalocyanines as medicinal photosensitizers: developments in the last five years 期刊论文 Xingshu Li;Bing-De Zheng;Xiao-Hui Peng;Song-Zi Li;Jia-Wen Ying;Yuanyuan Zhao;Jian-Dong Huang;Juyoung Yoon
25 Silicon(IV) phthalocyanines substituted axially with different nucleoside moieties. Effects of nucleoside type on the photosensitizing efficiencies and in vitro photodynamic activities 期刊论文 Bi-Yuan Zheng;Xiao-Min Shen;Dong-Mei Zhao;Yi-Bin Cai;Mei-Rong Ke;Jian-Dong Huang
26 Mono- and tetra-substituted zinc(II) phthalocyanines containing morpholinyl moieties: Synthesis, antifungal photodynamic activities, and structure-activity relationships 期刊论文 Zheng Bi-Yuan;Ke Mei-Rong;Lan Wen-Liang;Hou Lu;Guo Jun;Wan Dong-Hua;Huang Jian-Dong;Cheong Ling-Zhi;Huang JD
27 A pH-responsive stellate mesoporous silica based nanophotosensitizer for in vivo cancer diagnosis and targeted photodynamic therapy 期刊论文 Ai-Lan Lin;Song-Zi Li;Cai-Hong Xu;Xing-Shu Li;Bi-Yuan Zheng;Jun-Jie Gu;Mei-Rong Ke;Jian-Dong Huang
28 Facile Supramolecular Approach to Nucleic-Acid-Driven Activatable Nanotheranostics That Overcome Drawbacks of Photodynamic Therapy 期刊论文 Li Xingshu;Yu Sungsook;Lee Dayoung;Kim Gyoungmi;Lee Buhyun;Cho Yejin;Zheng Bi-Yuan;Ke Mei-Rong;Huang Jian-Dong;Nam Ki Taek;Chen Xiaoyuan;Yoon Juyoung
29 A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: a novel zinc(II) phthalocyanine containing octa-sulphonates 期刊论文 Li Xing-Shu; Ke Mei-Rong; Zhang Miao-Fen; Tang Qing-Qing; Zheng Bi-Yuan; Huang Jian-Dong
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